KEGG   PATHWAY: aprt00620
Entry
aprt00620                   Pathway                                
Name
Pyruvate metabolism - Amycolatopsis sp. FBCC-B4732
Class
Metabolism; Carbohydrate metabolism
Pathway map
aprt00620  Pyruvate metabolism
aprt00620

Module
aprt_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:aprt00620]
Other DBs
GO: 0006090
Organism
Amycolatopsis sp. FBCC-B4732 [GN:aprt]
Gene
MUY14_39630  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MUY14_16855  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
MUY14_08240  hypothetical protein [KO:K00169] [EC:1.2.7.1]
MUY14_08245  thiamine pyrophosphate-dependent enzyme [KO:K00170] [EC:1.2.7.1]
MUY14_08235  2-oxoacid:acceptor oxidoreductase family protein [KO:K00172] [EC:1.2.7.1]
MUY14_33875  2-oxoacid:acceptor oxidoreductase subunit alpha [KO:K00174] [EC:1.2.7.3 1.2.7.11]
MUY14_33880  2-oxoacid:ferredoxin oxidoreductase subunit beta [KO:K00175] [EC:1.2.7.3 1.2.7.11]
MUY14_25850  aceE; pyruvate dehydrogenase (acetyl-transferring), homodimeric type [KO:K00163] [EC:1.2.4.1]
MUY14_26580  pyruvate dehydrogenase [KO:K00163] [EC:1.2.4.1]
MUY14_25610  sucB; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase [KO:K00627] [EC:2.3.1.12]
MUY14_01880  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MUY14_25605  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MUY14_17690  acetaldehyde dehydrogenase (acetylating) [KO:K04073] [EC:1.2.1.10]
MUY14_08290  zinc-binding alcohol dehydrogenase family protein [KO:K13953] [EC:1.1.1.1]
MUY14_08810  zinc-binding dehydrogenase [KO:K00001] [EC:1.1.1.1]
MUY14_34365  NAD(P)-dependent alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
MUY14_07405  acetate kinase [KO:K00925] [EC:2.7.2.1]
MUY14_08485  acetate kinase [KO:K00925] [EC:2.7.2.1]
MUY14_24110  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
MUY14_32130  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MUY14_26970  acylphosphatase [KO:K01512] [EC:3.6.1.7]
MUY14_32385  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
MUY14_11280  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
MUY14_42405  aldehyde dehydrogenase family protein [KO:K00138] [EC:1.2.1.-]
MUY14_25855  alpha-hydroxy-acid oxidizing protein [KO:K00101] [EC:1.1.2.3]
MUY14_14460  pyruvate dehydrogenase [KO:K00156] [EC:1.2.5.1]
MUY14_19015  thiamine pyrophosphate-requiring protein [KO:K00156] [EC:1.2.5.1]
MUY14_01635  lactate 2-monooxygenase [KO:K00467] [EC:1.13.12.4]
MUY14_16580  MBL fold metallo-hydrolase [KO:K01069] [EC:3.1.2.6]
MUY14_41145  NAD-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
MUY14_44495  NADP-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
MUY14_27655  pyruvate carboxylase [KO:K01958] [EC:6.4.1.1]
MUY14_13800  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MUY14_23565  fumarate hydratase [KO:K01676] [EC:4.2.1.2]
MUY14_43960  class II fumarate hydratase [KO:K01679] [EC:4.2.1.2]
MUY14_37305  phosphoenolpyruvate carboxykinase (GTP) [KO:K01596] [EC:4.1.1.32]
MUY14_08520  ppsA; phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
MUY14_26915  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
MUY14_28285  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
MUY14_37390  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MUY14_43650  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MUY14_44840  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MUY14_01780  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MUY14_18580  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MUY14_23635  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
MUY14_23660  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MUY14_28635  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MUY14_39290  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
MUY14_27980  cimA; citramalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
aprt00010  Glycolysis / Gluconeogenesis
aprt00020  Citrate cycle (TCA cycle)
aprt00061  Fatty acid biosynthesis
aprt00250  Alanine, aspartate and glutamate metabolism
aprt00260  Glycine, serine and threonine metabolism
aprt00290  Valine, leucine and isoleucine biosynthesis
aprt00300  Lysine biosynthesis
aprt00630  Glyoxylate and dicarboxylate metabolism
aprt00640  Propanoate metabolism
aprt00650  Butanoate metabolism
aprt00760  Nicotinate and nicotinamide metabolism
aprt01056  Biosynthesis of type II polyketide backbone
aprt01059  Biosynthesis of enediyne antibiotics
KO pathway
ko00620   
LinkDB

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