KEGG   PATHWAY: bceo00630
Entry
bceo00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia cenocepacia H111
Class
Metabolism; Carbohydrate metabolism
Pathway map
bceo00630  Glyoxylate and dicarboxylate metabolism
bceo00630

Module
bceo_M00012  Glyoxylate cycle [PATH:bceo00630]
bceo_M00621  Glycine cleavage system [PATH:bceo00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia cenocepacia H111 [GN:bceo]
Gene
I35_5447  Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
I35_2045  aceA; Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
I35_7862  Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases [KO:K01895] [EC:6.2.1.1]
I35_1201  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
I35_2210  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
I35_6268  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
I35_7673  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
I35_6079  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
I35_6701  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
I35_2049  aceB; Malate synthase [KO:K01638] [EC:2.3.3.9]
I35_4885  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
I35_4730  similar to Citrate synthase [KO:K01647] [EC:2.3.3.1]
I35_2604  hypothetical protein [KO:K01647] [EC:2.3.3.1]
I35_4892  gltA; Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
I35_6588  prpC; 2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
I35_4881  acnA; Aconitate hydratase @ 2-methylisocitrate dehydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
I35_5712  acnB; Aconitate hydratase(EC:4.2.1.3) [KO:K01682] [EC:4.2.1.3 4.2.1.99]
I35_1780  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I35_5943  3-ketoacyl-CoA thiolase @ Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I35_7860  Acetyl-CoA C-acyltransferase @ Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I35_5484  3-ketoacyl-CoA thiolase @ Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I35_5490  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
I35_1898  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
I35_2839  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I35_7773  bktB; 3-ketoacyl-CoA thiolase @ Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I35_1779  phbB; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
I35_2838  phbB; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
I35_6697  glcD; Glycolate dehydrogenase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
I35_0586  glcD; Glycolate dehydrogenase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
I35_6698  glcE; Glycolate dehydrogenase,FAD-binding subunit GlcE [KO:K11472] [EC:1.1.99.14]
I35_0585  glcE; Glycolate dehydrogenase, FAD-binding subunit GlcE [KO:K11472] [EC:1.1.99.14]
I35_6699  glcF; Glycolate dehydrogenase,iron-sulfur subunit GlcF [KO:K11473] [EC:1.1.99.14]
I35_0584  glcF; Glycolate dehydrogenase, iron-sulfur subunit GlcF [KO:K11473] [EC:1.1.99.14]
I35_4851  Catalase [KO:K03781] [EC:1.11.1.6]
I35_3257  Catalase [KO:K03781] [EC:1.11.1.6]
I35_7583  Catalase [KO:K03781] [EC:1.11.1.6]
I35_7403  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
I35_3033  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
I35_1718  tkrA; 2-ketogluconate 6-phosphate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
I35_0972  Glyoxylate reductase / Glyoxylate reductase / Hydroxypyruvate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
I35_1661  hprA; Hydroxypyruvate reductase [KO:K00018] [EC:1.1.1.29]
I35_0981  Similar to phosphoglycolate phosphatase,clustered with ribosomal large subunit pseudouridine synthase C [KO:K01091] [EC:3.1.3.18]
I35_5796  Haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
I35_5908  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
I35_0390  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
I35_5935  puuA; glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
I35_2151  glnA; Glutamine synthetase type I [KO:K01915] [EC:6.3.1.2]
I35_2165  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
I35_3068  Gamma-glutamyl-putrescine synthetase [KO:K01915] [EC:6.3.1.2]
I35_7812  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
I35_7821  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
I35_0654  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
I35_6217  glyA; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
I35_0075  gcvP; Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) [KO:K00281] [EC:1.4.4.2]
I35_0077  gcvT; Aminomethyltransferase (glycine cleavage system T protein) [KO:K00605] [EC:2.1.2.10]
I35_2136  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
I35_1415  odhL; Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase [KO:K00382] [EC:1.8.1.4]
I35_1126  lpdV; Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase [KO:K00382] [EC:1.8.1.4]
I35_0076  gcvH; Glycine cleavage system H protein [KO:K02437]
I35_1869  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
I35_1870  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
I35_1871  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
I35_1920  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
I35_7292  Tartrate dehydrogenase / Tartrate decarboxylase / D-malic enzyme [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
I35_4642  Tartrate dehydrogenase / Tartrate decarboxylase / D-malic enzyme [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
I35_4016  Tartrate dehydrogenase / Tartrate decarboxylase / D-malic enzyme [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
I35_0509  eda; 4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
I35_5640  Oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
I35_0896  fdsD; NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
I35_0897  fdsA; NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
I35_4936  Formate dehydrogenase O alpha subunit [KO:K00123] [EC:1.17.1.9]
I35_0898  fdsB; NAD-dependent formate dehydrogenase beta subunit [KO:K00124]
I35_4937  fdnH; Formate dehydrogenase O beta subunit [KO:K00124]
I35_0899  fdsG; NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
I35_4938  fdnI; Formate dehydrogenase O gamma subunit [KO:K00127]
I35_1665  Kf-pending protein [KO:K01432] [EC:3.5.1.9]
I35_2647  Kynurenine formamidase, bacterial [KO:K07130] [EC:3.5.1.9]
I35_2848  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
I35_6206  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
I35_2168  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bceo00010  Glycolysis / Gluconeogenesis
bceo00020  Citrate cycle (TCA cycle)
bceo00030  Pentose phosphate pathway
bceo00053  Ascorbate and aldarate metabolism
bceo00071  Fatty acid degradation
bceo00230  Purine metabolism
bceo00250  Alanine, aspartate and glutamate metabolism
bceo00260  Glycine, serine and threonine metabolism
bceo00620  Pyruvate metabolism
bceo00710  Carbon fixation by Calvin cycle
bceo00750  Vitamin B6 metabolism
bceo00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system