KEGG   PATHWAY: bhg02024
Entry
bhg02024                    Pathway                                
Name
Quorum sensing - Burkholderia humptydooensis FDAARGOS_899
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
bhg02024  Quorum sensing
bhg02024

Other DBs
GO: 0009372
Organism
Burkholderia humptydooensis FDAARGOS_899 [GN:bhg]
Gene
I6G56_09740  hfq; RNA chaperone Hfq [KO:K03666]
I6G56_11935  hfq; RNA chaperone Hfq [KO:K03666]
I6G56_18090  anthranilate synthase component I [KO:K01657] [EC:4.1.3.27]
I6G56_18095  aminodeoxychorismate/anthranilate synthase component II [KO:K01658] [EC:4.1.3.27]
I6G56_31560  MBL fold metallo-hydrolase [KO:K20257] [EC:3.1.2.32]
I6G56_23555  bspI1; N-acylhomoserine lactone synthase BspI1 [KO:K13061] [EC:2.3.1.184]
I6G56_01105  N-acylhomoserine lactone synthase [KO:K13061] [EC:2.3.1.184]
I6G56_21170  alpha/beta hydrolase [KO:K18100] [EC:2.4.1.-]
I6G56_25360  alpha/beta hydrolase [KO:K18100] [EC:2.4.1.-]
I6G56_21175  glycosyltransferase [KO:K18101] [EC:2.4.1.-]
I6G56_25355  glycosyltransferase [KO:K18101] [EC:2.4.1.-]
I6G56_16085  glycosyltransferase family 2 protein [KO:K12990] [EC:2.4.1.-]
I6G56_21185  glycosyltransferase family 2 protein [KO:K12990] [EC:2.4.1.-]
I6G56_25345  glycosyltransferase family 2 protein [KO:K12990] [EC:2.4.1.-]
I6G56_25120  peptidoglycan DD-metalloendopeptidase family protein [KO:K08642] [EC:3.4.24.-]
I6G56_16865  aroG; 3-deoxy-7-phosphoheptulonate synthase AroG [KO:K01626] [EC:2.5.1.54]
I6G56_21545  3-deoxy-7-phosphoheptulonate synthase [KO:K01626] [EC:2.5.1.54]
I6G56_16500  flagellar transcriptional regulator FlhD [KO:K02403]
I6G56_19540  flhC; flagellar transcriptional regulator FlhC [KO:K02402]
I6G56_06935  kdpE; two-component system response regulator KdpE [KO:K07667]
I6G56_15860  ABC transporter substrate-binding protein [KO:K02055]
I6G56_26055  ABC transporter substrate-binding protein [KO:K02055]
I6G56_30725  extracellular solute-binding protein [KO:K02055]
I6G56_31820  ABC transporter substrate-binding protein [KO:K02055]
I6G56_02020  polyamine ABC transporter substrate-binding protein [KO:K02055]
I6G56_08210  ABC transporter substrate-binding protein [KO:K02055]
I6G56_15840  ABC transporter permease [KO:K02053]
I6G56_26030  ABC transporter permease [KO:K02053]
I6G56_30715  ABC transporter permease subunit [KO:K02053]
I6G56_30730  ABC transporter permease subunit [KO:K02053]
I6G56_31830  ABC transporter permease [KO:K02053]
I6G56_08190  ABC transporter permease subunit [KO:K02053]
I6G56_08205  ABC transporter permease [KO:K02053]
I6G56_15835  ABC transporter permease [KO:K02054]
I6G56_26035  ABC transporter permease [KO:K02054]
I6G56_31825  ABC transporter permease [KO:K02054]
I6G56_15830  ABC transporter ATP-binding protein [KO:K02052]
I6G56_26050  ABC transporter ATP-binding protein [KO:K02052]
I6G56_30720  ABC transporter ATP-binding protein [KO:K02052]
I6G56_31815  ABC transporter ATP-binding protein [KO:K02052]
I6G56_08185  ABC transporter ATP-binding protein [KO:K02052]
I6G56_10560  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
I6G56_14230  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
I6G56_19415  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
I6G56_19990  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
I6G56_21995  ABC transporter substrate-binding protein [KO:K01999]
I6G56_23995  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
I6G56_25145  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
I6G56_28950  ABC transporter substrate-binding protein [KO:K01999]
I6G56_01390  ABC transporter substrate-binding protein [KO:K01999]
I6G56_01410  ABC transporter substrate-binding protein [KO:K01999]
I6G56_01745  ABC transporter substrate-binding protein [KO:K01999]
I6G56_05835  ABC transporter substrate-binding protein [KO:K01999]
I6G56_07085  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
I6G56_01395  hypothetical protein [KO:K01999]
I6G56_09170  branched-chain amino acid ABC transporter permease [KO:K01997]
I6G56_22000  ABC transporter permease [KO:K01997 K01998]
I6G56_25140  livH; high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997]
I6G56_28945  branched-chain amino acid ABC transporter permease [KO:K01997]
I6G56_01385  branched-chain amino acid ABC transporter permease [KO:K01997]
I6G56_01405  branched-chain amino acid ABC transporter permease [KO:K01997]
I6G56_01740  branched-chain amino acid ABC transporter permease [KO:K01997]
I6G56_05705  branched-chain amino acid ABC transporter permease [KO:K01997]
I6G56_09175  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
I6G56_25135  high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998]
I6G56_28940  branched-chain amino acid ABC transporter permease [KO:K01998]
I6G56_01380  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
I6G56_01400  branched-chain amino acid ABC transporter permease [KO:K01998]
I6G56_01735  branched-chain amino acid ABC transporter permease [KO:K01998]
I6G56_05710  ABC transporter ATP-binding protein [KO:K01998]
I6G56_22005  ABC transporter ATP-binding protein [KO:K01995]
I6G56_25130  livG; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG [KO:K01995]
I6G56_28935  ABC transporter ATP-binding protein [KO:K01995]
I6G56_01420  ABC transporter ATP-binding protein [KO:K01995]
I6G56_01730  ATP-binding cassette domain-containing protein [KO:K01995]
I6G56_05715  ABC transporter ATP-binding protein [KO:K01995]
I6G56_09180  ABC transporter ATP-binding protein [KO:K01996]
I6G56_22010  ABC transporter ATP-binding protein [KO:K01996]
I6G56_25125  ABC transporter ATP-binding protein [KO:K01996]
I6G56_28930  ABC transporter ATP-binding protein [KO:K01996]
I6G56_01375  ABC transporter ATP-binding protein [KO:K01996]
I6G56_01415  ABC transporter ATP-binding protein [KO:K01996]
I6G56_01725  ATP-binding cassette domain-containing protein [KO:K01996]
I6G56_05720  ABC transporter ATP-binding protein [KO:K01996]
I6G56_23545  bpsR; autoinducer-binding transcriptional regulator BpsR [KO:K19666]
I6G56_20145  GNAT family N-acetyltransferase [KO:K20250] [EC:2.3.1.184]
I6G56_20150  bpsR3; N-acyl-homoserine lactone dependent regulator BpsR3 [KO:K19731]
I6G56_20280  M4 family metallopeptidase [KO:K20273]
I6G56_25205  M36 family metallopeptidase [KO:K20274]
I6G56_09755  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
I6G56_18005  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
I6G56_07520  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
I6G56_05390  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
I6G56_28285  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
I6G56_05490  Crp/Fnr family transcriptional regulator [KO:K10914]
I6G56_05190  transcriptional repressor [KO:K09823]
I6G56_07425  IclR family transcriptional regulator [KO:K20329]
I6G56_31595  helix-turn-helix transcriptional regulator [KO:K20330]
I6G56_22305  GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
I6G56_23565  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
I6G56_22300  WD40 repeat domain-containing protein [KO:K20332]
I6G56_22290  SUMF1/EgtB/PvdO family nonheme iron enzyme [KO:K20333]
I6G56_15670  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
I6G56_22285  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
I6G56_22325  efflux RND transporter periplasmic adaptor subunit [KO:K18306]
I6G56_22320  efflux RND transporter permease subunit [KO:K18307]
I6G56_10255  efflux transporter outer membrane subunit [KO:K18139]
I6G56_22315  oprB; efflux RND transporter outer membrane subunit OprB [KO:K18139]
I6G56_05145  oprB; efflux RND transporter outer membrane subunit OprB [KO:K18139]
I6G56_27695  efflux transporter outer membrane subunit [KO:K18139]
I6G56_30305  peptide ABC transporter substrate-binding protein [KO:K15580]
I6G56_30310  ABC transporter permease subunit [KO:K15581]
I6G56_30315  ABC transporter permease subunit [KO:K15582]
I6G56_30320  ABC transporter ATP-binding protein [KO:K15583]
I6G56_30325  ATP-binding cassette domain-containing protein [KO:K10823]
I6G56_21410  ABC transporter substrate-binding protein [KO:K02035]
I6G56_23145  ABC transporter substrate-binding protein [KO:K02035]
I6G56_23230  ABC transporter substrate-binding protein [KO:K02035]
I6G56_21405  ABC transporter permease [KO:K02033]
I6G56_23235  ABC transporter permease [KO:K02033]
I6G56_21400  ABC transporter permease [KO:K02034]
I6G56_23240  ABC transporter permease [KO:K02034]
I6G56_21395  ABC transporter ATP-binding protein [KO:K02031]
I6G56_23245  ABC transporter ATP-binding protein [KO:K02031]
I6G56_21390  ABC transporter ATP-binding protein [KO:K02032]
I6G56_23250  ABC transporter ATP-binding protein [KO:K02032]
I6G56_01930  yidC; membrane protein insertase YidC [KO:K03217]
I6G56_23100  S8 family peptidase [KO:K14645] [EC:3.4.21.-]
I6G56_28020  S8 family peptidase [KO:K14645] [EC:3.4.21.-]
I6G56_19105  secE; preprotein translocase subunit SecE [KO:K03073]
I6G56_07110  secG; preprotein translocase subunit SecG [KO:K03075]
I6G56_18935  secY; preprotein translocase subunit SecY [KO:K03076]
I6G56_17020  yajC; preprotein translocase subunit YajC [KO:K03210]
I6G56_17895  secA; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
I6G56_03955  ftsY; signal recognition particle-docking protein FtsY [KO:K03110]
I6G56_03675  secB; protein-export chaperone SecB [KO:K03071]
I6G56_17650  ffh; signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
I6G56_09790  phosphoesterase [KO:K01114] [EC:3.1.4.3]
I6G56_14225  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
I6G56_21430  alkaline phosphatase family protein [KO:K01114] [EC:3.1.4.3]
I6G56_24170  alkaline phosphatase family protein [KO:K01114] [EC:3.1.4.3]
I6G56_29705  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
I6G56_03140  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
I6G56_07775  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
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PMID:15522077
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Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
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Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
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Mol Microbiol 54:921-34 (2004)
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Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
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Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
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Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
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Stauff DL, Bassler BL
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Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
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J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
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PMID:21504831
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Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
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A strategy for antagonizing quorum sensing.
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Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
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Hao G, Burr TJ
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Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
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J Bacteriol 188:2173-83 (2006)
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Savka MA, Le PT, Burr TJ
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LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
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Curr Microbiol 62:101-10 (2011)
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PMID:26579084
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Le KY, Otto M
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Quorum-sensing regulation in staphylococci-an overview.
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Front Microbiol 6:1174 (2015)
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Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
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RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
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Mol Cell 32:150-8 (2008)
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Darkoh C, DuPont HL, Norris SJ, Kaplan HB
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Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
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MBio 6:e02569 (2015)
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PMID:25824838
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Vidal JE, Shak JR, Canizalez-Roman A
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The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
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Infect Immun 83:2430-42 (2015)
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Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
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Virulence gene regulation by the agr system in Clostridium perfringens.
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J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
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PMID:22736963
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Li YH, Tian X
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Quorum sensing and bacterial social interactions in biofilms.
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Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
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Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
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Properties and biological role of streptococcal fratricins.
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Appl Environ Microbiol 78:3515-22 (2012)
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Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
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Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
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J Oral Microbiol 6:26189 (2014)
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Jimenez JC, Federle MJ
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Quorum sensing in group A Streptococcus.
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Front Cell Infect Microbiol 4:127 (2014)
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Peptide pheromone signaling in Streptococcus and Enterococcus.
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FEMS Microbiol Rev 38:473-92 (2014)
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The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
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Mol Microbiol 28:1323-34 (1998)
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Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
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Mol Microbiol 21:1087-99 (1996)
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PMID:22636768
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Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
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Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
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J Bacteriol 194:3961-71 (2012)
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PMID:22016844
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Clewell DB
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Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
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Mob Genet Elements 1:38-54 (2011)
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PMID:20734751
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Complex nature of enterococcal pheromone-responsive plasmids.
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Pol J Microbiol 59:79-87 (2010)
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Roux A, Payne SM, Gilmore MS
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Microbial telesensing: probing the environment for friends, foes, and food.
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Cell Host Microbe 6:115-24 (2009)
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PMID:25089349
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Slamti L, Perchat S, Huillet E, Lereclus D
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Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
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Toxins (Basel) 6:2239-55 (2014)
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PMID:20030732
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Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
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FEMS Microbiol Rev 34:134-49 (2010)
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PMID:12897006
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Stephenson S, Mueller C, Jiang M, Perego M
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Molecular analysis of Phr peptide processing in Bacillus subtilis.
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J Bacteriol 185:4861-71 (2003)
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PMID:17666034
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Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
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Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
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Mol Microbiol 65:1321-33 (2007)
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PMID:15374644
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Kleerebezem M
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Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
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Peptides 25:1405-14 (2004)
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PMID:23125205
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Rutherford ST, Bassler BL
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Bacterial quorum sensing: its role in virulence and possibilities for its control.
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Cold Spring Harb Perspect Med 2:a012427 (2012)
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PMID:23471618
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LaSarre B, Federle MJ
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Exploiting quorum sensing to confuse bacterial pathogens.
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Microbiol Mol Biol Rev 77:73-111 (2013)
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PMID:18781869
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Sifri CD
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Healthcare epidemiology: quorum sensing: bacteria talk sense.
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Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
Related
pathway
bhg00405  Phenazine biosynthesis
bhg02040  Flagellar assembly
KO pathway
ko02024   
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