KEGG   PATHWAY: bpk00630
Entry
bpk00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia pseudomallei NCTC 13179
Class
Metabolism; Carbohydrate metabolism
Pathway map
bpk00630  Glyoxylate and dicarboxylate metabolism
bpk00630

Module
bpk_M00012  Glyoxylate cycle [PATH:bpk00630]
bpk_M00621  Glycine cleavage system [PATH:bpk00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia pseudomallei NCTC 13179 [GN:bpk]
Gene
BBK_2776  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BBK_3873  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BBK_5595  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BBK_138  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BBK_2772  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BBK_4441  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BBK_4434  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BBK_616  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
BBK_5401  2-methylcitrate synthase/citrate synthase II family protein [KO:K01659] [EC:2.3.3.5]
BBK_4445  acnA; aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
BBK_2921  acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBK_3032  acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBK_3038  acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBK_1093  acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBK_1370  acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBK_3033  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BBK_4654  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BBK_2086  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
BBK_2085  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
BBK_2084  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
BBK_6154  katB; catalase [KO:K03781] [EC:1.11.1.6]
BBK_4990  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
BBK_1359  catalase family protein [KO:K03781] [EC:1.11.1.6]
BBK_1129  ghrA; glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BBK_3077  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BBK_2494  NADP oxidoreductase coenzyme F420-dependent family protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BBK_1863  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BBK_2503  HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
BBK_5676  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BBK_2621  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BBK_2639  glnA; glnA: glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BBK_3944  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
BBK_2174  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
BBK_1501  gcvP; gcvP: glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BBK_1503  gcvT; gcvT: glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
BBK_3405  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BBK_2659  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BBK_5050  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BBK_1502  gcvH; gcvH: glycine cleavage system H protein [KO:K02437]
BBK_2949  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BBK_2948  hyi; OH-pyruv-isom: hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BBK_2947  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BBK_2894  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BBK_5317  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BBK_5149  TTC: tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BBK_1991  eda; eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BBK_3470  oxdD; oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]
BBK_2415  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
BBK_2416  fdh-alpha: formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BBK_4380  formate-DH-alph: formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BBK_4381  Tat (twin-arginine translocation) pathway signal sequence domain protein [KO:K00123] [EC:1.17.1.9]
BBK_2417  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
BBK_4379  fdxH; FDH-beta: formate dehydrogenase, beta subunit [KO:K00124]
BBK_4378  formate-DH-gamm: formate dehydrogenase, gamma subunit [KO:K00127]
BBK_2418  respiratory-chain NADH dehydrogenase 24 Kd subunit [KO:K00127]
BBK_100  alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]
BBK_658  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BBK_3933  purU; purU: formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BBK_916  purU; purU: formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BBK_2619  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bpk00010  Glycolysis / Gluconeogenesis
bpk00020  Citrate cycle (TCA cycle)
bpk00030  Pentose phosphate pathway
bpk00053  Ascorbate and aldarate metabolism
bpk00071  Fatty acid degradation
bpk00230  Purine metabolism
bpk00250  Alanine, aspartate and glutamate metabolism
bpk00260  Glycine, serine and threonine metabolism
bpk00620  Pyruvate metabolism
bpk00710  Carbon fixation by Calvin cycle
bpk00750  Vitamin B6 metabolism
bpk00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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