KEGG   PATHWAY: bps00630
Entry
bps00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia pseudomallei K96243
Class
Metabolism; Carbohydrate metabolism
Pathway map
bps00630  Glyoxylate and dicarboxylate metabolism
bps00630

Module
bps_M00012  Glyoxylate cycle [PATH:bps00630]
bps_M00621  Glycine cleavage system [PATH:bps00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia pseudomallei K96243 [GN:bps]
Gene
BPSL2188  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BPSS0375  acoE; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BPSL1380  putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
BPSS0618  AMP-binding enzyme [KO:K01895] [EC:6.2.1.1]
BPSL2192  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BPSS1722  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BPSS1715  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
BPSL0890  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
BPSS0207  prpC; 2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
BPSS1726  citB; aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
BPSL1535  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BPSL1540  putative beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
BPSL1426  putative thiolase [KO:K00626] [EC:2.3.1.9]
BPSL0371  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BPSL0062  beta-ketoadipyl CoA thiolase [KO:K00626] [EC:2.3.1.9]
BPSL1536  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BPSS1916  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BPSL2843  glcD; putative glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
BPSL2844  glcE; putative glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
BPSL2845  glcF; putative glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BPSS2214  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
BPSS0993  katB; catalase precursor [KO:K03781] [EC:1.11.1.6]
BPSL0071  putative catalase [KO:K03781] [EC:1.11.1.6]
BPSL0334  conserved hypothetical protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BPSL1577  tkrA; 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BPSL2459  putative 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BPSL3049  putative hydrolase [KO:K01091] [EC:3.1.3.18]
BPSL2450  haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
BPSL2318  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BPSS0469  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BPSL2336  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BPSL2758  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BPSS0547  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BPSL3362  gcvP; glycine dehydrogenase [decarboxylating] [KO:K00281] [EC:1.4.4.2]
BPSL3360  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
BPSL1907  odhL; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BPSS2270  lpdV; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BPSL2299  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BPSL3361  gcvH; glycine cleavage system H protein [KO:K02437]
BPSL1452  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BPSL1451  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BPSL1450  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BPSS0127  glxK; glycerate kinase 1 [KO:K00865] [EC:2.7.1.165]
BPSL1401  putative kinase [KO:K00865] [EC:2.7.1.165]
BPSS0011  putative tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BPSL2931  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BPSS0965  putative oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
BPSL2531  fdsD; NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
BPSL2530  fdsA; NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
BPSS1667  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
BPSL2529  fdsB; NAD-dependent formate dehydrogenase beta subunit [KO:K00124]
BPSS1666  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
BPSL2528  fdsG; NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
BPSS1665  fdoI; formate dehydrogenase, cytochrome b556 (FDO) subunit [KO:K00127]
BPSL0848  conserved hypothetical protein [KO:K07130] [EC:3.5.1.9]
BPSL0543  putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BPSS0558  putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BPSL2338  HutG protein [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bps00010  Glycolysis / Gluconeogenesis
bps00020  Citrate cycle (TCA cycle)
bps00030  Pentose phosphate pathway
bps00053  Ascorbate and aldarate metabolism
bps00071  Fatty acid degradation
bps00230  Purine metabolism
bps00250  Alanine, aspartate and glutamate metabolism
bps00260  Glycine, serine and threonine metabolism
bps00620  Pyruvate metabolism
bps00710  Carbon fixation by Calvin cycle
bps00750  Vitamin B6 metabolism
bps00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system