KEGG   PATHWAY: burk00630
Entry
burk00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia sp. JP2-270
Class
Metabolism; Carbohydrate metabolism
Pathway map
burk00630  Glyoxylate and dicarboxylate metabolism
burk00630

Module
burk_M00012  Glyoxylate cycle [PATH:burk00630]
burk_M00621  Glycine cleavage system [PATH:burk00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia sp. JP2-270 [GN:burk]
Gene
DM992_10125  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
DM992_22905  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
DM992_09150  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM992_14910  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DM992_22475  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DM992_23395  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM992_35330  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
DM992_39785  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM992_10105  malate synthase A [KO:K01638] [EC:2.3.3.9]
DM992_25880  malate synthase G [KO:K01638] [EC:2.3.3.9]
DM992_30510  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DM992_07420  citrate synthase [KO:K01647] [EC:2.3.3.1]
DM992_30545  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DM992_25135  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
DM992_30490  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
DM992_31265  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
DM992_06085  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_11010  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_11065  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_11695  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_11725  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_13990  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_32545  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_32575  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_35340  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_36795  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DM992_06090  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
DM992_11700  3-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
DM992_12360  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
DM992_39190  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DM992_25855  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
DM992_00335  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
DM992_38455  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
DM992_25860  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
DM992_00340  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
DM992_38460  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
DM992_25865  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
DM992_00345  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
DM992_38465  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
DM992_30330  catalase [KO:K03781] [EC:1.11.1.6]
DM992_03885  catalase [KO:K03781] [EC:1.11.1.6]
DM992_05055  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DM992_34180  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DM992_12090  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DM992_16080  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DM992_12625  glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
DM992_16030  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DM992_20995  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DM992_21895  hydrolase [KO:K01091] [EC:3.1.3.18]
DM992_01390  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
DM992_04890  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DM992_09370  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DM992_09485  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DM992_17855  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DM992_22005  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DM992_17595  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DM992_23135  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DM992_27790  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DM992_35355  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DM992_35360  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
DM992_03190  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
DM992_35350  glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DM992_03180  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DM992_09560  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM992_13650  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM992_15360  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM992_35365  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DM992_03185  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DM992_11235  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DM992_11230  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DM992_11225  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DM992_10890  glycerate kinase [KO:K00865] [EC:2.7.1.165]
DM992_26070  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DM992_29195  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DM992_00705  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DM992_31725  cupin [KO:K01569] [EC:4.1.1.2]
DM992_16465  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
DM992_16460  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DM992_30810  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
DM992_20510  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DM992_16455  formate dehydrogenase [KO:K00124]
DM992_20505  NADH-quinone oxidoreductase subunit D [KO:K00124]
DM992_30815  fdxH; formate dehydrogenase subunit beta [KO:K00124]
DM992_16450  formate dehydrogenase [KO:K00127]
DM992_30820  formate dehydrogenase subunit gamma [KO:K00127]
DM992_12605  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
DM992_07070  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
DM992_05980  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM992_23080  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM992_20730  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
DM992_09355  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
DM992_17845  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
DM992_38270  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
burk00010  Glycolysis / Gluconeogenesis
burk00020  Citrate cycle (TCA cycle)
burk00030  Pentose phosphate pathway
burk00053  Ascorbate and aldarate metabolism
burk00071  Fatty acid degradation
burk00230  Purine metabolism
burk00250  Alanine, aspartate and glutamate metabolism
burk00260  Glycine, serine and threonine metabolism
burk00620  Pyruvate metabolism
burk00710  Carbon fixation by Calvin cycle
burk00750  Vitamin B6 metabolism
burk00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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