KEGG   PATHWAY: cag00630
Entry
cag00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Chloroflexus aggregans
Class
Metabolism; Carbohydrate metabolism
Pathway map
cag00630  Glyoxylate and dicarboxylate metabolism
cag00630

Module
cag_M00012  Glyoxylate cycle [PATH:cag00630]
cag_M00621  Glycine cleavage system [PATH:cag00630]
Other DBs
GO: 0046487 0043648
Organism
Chloroflexus aggregans [GN:cag]
Gene
Cagg_0040  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Cagg_3789  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Cagg_3782  malate synthase A [KO:K01638] [EC:2.3.3.9]
Cagg_2290  malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
Cagg_3738  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Cagg_3721  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
Cagg_1143  acetyl-CoA acetyltransferase-like protein [KO:K00626] [EC:2.3.1.9]
Cagg_1950  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Cagg_2466  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Cagg_1951  short-chain dehydrogenase/reductase SDR [KO:K00023] [EC:1.1.1.36]
Cagg_0370  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
Cagg_0981  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Cagg_1326  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
Cagg_1328  HpcH/HpaI aldolase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Cagg_2537  acetyl-CoA carboxylase, biotin carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Cagg_1348  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Cagg_1349  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Cagg_0587  cobalamin B12-binding domain protein [KO:K01849] [EC:5.4.99.2]
Cagg_2545  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Cagg_1531  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Cagg_1893  D-lactate dehydrogenase (cytochrome) [KO:K00104] [EC:1.1.99.14]
Cagg_1530  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Cagg_1892  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Cagg_1528  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Cagg_2722  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
Cagg_0760  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
Cagg_0145  Glutamate synthase (ferredoxin) [KO:K00284] [EC:1.4.7.1]
Cagg_0422  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Cagg_1793  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Cagg_2657  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Cagg_3468  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Cagg_0251  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
Cagg_0249  Glycine dehydrogenase (decarboxylating) [KO:K00283] [EC:1.4.4.2]
Cagg_0253  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Cagg_1128  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Cagg_0252  glycine cleavage system H protein [KO:K02437]
Cagg_3455  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Cagg_3457  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Cagg_1301  Xylose isomerase domain protein TIM barrel [KO:K01816] [EC:5.3.1.22]
Cagg_3389  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cag00010  Glycolysis / Gluconeogenesis
cag00020  Citrate cycle (TCA cycle)
cag00030  Pentose phosphate pathway
cag00053  Ascorbate and aldarate metabolism
cag00071  Fatty acid degradation
cag00230  Purine metabolism
cag00250  Alanine, aspartate and glutamate metabolism
cag00260  Glycine, serine and threonine metabolism
cag00620  Pyruvate metabolism
cag00710  Carbon fixation by Calvin cycle
cag00750  Vitamin B6 metabolism
cag00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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