KEGG   PATHWAY: cbl00230
Entry
cbl00230                    Pathway                                
Name
Purine metabolism - Clostridium botulinum A3 Loch Maree
Class
Metabolism; Nucleotide metabolism
Pathway map
cbl00230  Purine metabolism
cbl00230

Module
cbl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cbl00230]
cbl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cbl00230]
cbl_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cbl00230]
cbl_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cbl00230]
Other DBs
GO: 0006163 0042278
Organism
Clostridium botulinum A3 Loch Maree [GN:cbl]
Gene
CLK_1255  hydrolase, NUDIX family [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CLK_3677  hydrolase, NUDIX family [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CLK_2509  phosphoglucomutase/phosphomannomutase family protein [KO:K01835] [EC:5.4.2.2]
CLK_3103  phosphoglucomutase/phosphomannomutase family protein [KO:K01835] [EC:5.4.2.2]
CLK_3013  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CLK_2272  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CLK_2304  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CLK_2268  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CLK_2270  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CLK_1965  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CLK_2271  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CLK_2274  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
CLK_2273  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CLK_1771  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CLK_2269  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CLK_2453  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CLK_1459  phosphoribosyl transferase domain protein [KO:K00759] [EC:2.4.2.7]
CLK_3415  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
CLK_1250  punA; purine nucleoside phosphorylase I, inosine and guanosine-specific [KO:K03783] [EC:2.4.2.1]
CLK_2579  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
CLK_1912  conserved hypothetical protein TIGR00726 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CLK_2474  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CLK_2990  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CLK_2712  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CLK_2678  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
CLK_3506  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
CLK_0579  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
CLK_0727  putative xanthine dehydrogenase, molybdopterin-binding subunit [KO:K00087] [EC:1.17.1.4]
CLK_0728  putative xanthine dehydrogenase, FAD-binding subunit [KO:K13479] [EC:1.17.1.4]
CLK_0729  putative xanthine dehydrogenase, iron-sulfur binding subunit [KO:K13480]
CLK_2711  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
CLK_0730  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
CLK_A0185  putative guanylate kinase [KO:K00942] [EC:2.7.4.8]
CLK_1896  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CLK_2201  nrdA; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
CLK_2200  nrdB; ribonucleoside-diphosphate reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
CLK_3268  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
CLK_2324  deoxynucleotide triphosphohydrolase family protein [KO:K01129] [EC:3.1.5.1]
CLK_2452  putative GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CLK_3362  RelA/SpoT domain protein [KO:K07816] [EC:2.7.6.5]
CLK_3370  putative adenylyl cyclase CyaB [KO:K05873] [EC:4.6.1.1]
CLK_3100  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CLK_0436  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CLK_3488  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
CLK_2903  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
CLK_2288  conserved hypothetical protein [KO:K06928] [EC:3.6.1.15]
CLK_1979  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cbl00030  Pentose phosphate pathway
cbl00220  Arginine biosynthesis
cbl00250  Alanine, aspartate and glutamate metabolism
cbl00260  Glycine, serine and threonine metabolism
cbl00340  Histidine metabolism
cbl00630  Glyoxylate and dicarboxylate metabolism
cbl00730  Thiamine metabolism
cbl00740  Riboflavin metabolism
cbl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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