KEGG   PATHWAY: ccad00630
Entry
ccad00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cervus canadensis (wapiti)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ccad00630  Glyoxylate and dicarboxylate metabolism
ccad00630

Module
ccad_M00621  Glycine cleavage system [PATH:ccad00630]
ccad_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ccad00630]
Other DBs
GO: 0046487 0043648
Organism
Cervus canadensis (wapiti) [GN:ccad]
Gene
122447802  ACSS1; acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
122448092  ACSS2; acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
122441825  MDH1; malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
122433041  MDH2; malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
122427308  CS; citrate synthase, mitochondrial isoform X1 [KO:K01647] [EC:2.3.3.1]
122423078  ACO2; aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
122453014  cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
122449485  ACAT1; acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
122433847  ACAT2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
122419722  MCEE; methylmalonyl-CoA epimerase, mitochondrial isoform X1 [KO:K05606] [EC:5.1.99.1]
122447653  PCCA; propionyl-CoA carboxylase alpha chain, mitochondrial isoform X1 [KO:K01965] [EC:6.4.1.3]
122445296  PCCB; propionyl-CoA carboxylase beta chain, mitochondrial isoform X1 [KO:K01966] [EC:6.4.1.3 2.1.3.15]
122429617  MMUT; methylmalonyl-CoA mutase, mitochondrial isoform X1 [KO:K01847] [EC:5.4.99.2]
122448681  HAO1; hydroxyacid oxidase 1 isoform X1 [KO:K11517] [EC:1.1.3.15]
122435377  HAO2; hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
122449611  CAT; catalase [KO:K03781] [EC:1.11.1.6]
122452886  GRHPR; glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
122433216  glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
122428409  AGXT; serine--pyruvate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
122434077  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
122452055  GLUL; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
122444022  SHMT1; serine hydroxymethyltransferase, cytosolic [KO:K00600] [EC:2.1.2.1]
122427446  SHMT2; serine hydroxymethyltransferase, mitochondrial isoform X1 [KO:K00600] [EC:2.1.2.1]
122453186  GLDC; glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
122424959  AMT; aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
122438319  DLD; dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
122448859  glycine cleavage system H protein, mitochondrial [KO:K02437]
122420997  GCSH; glycine cleavage system H protein, mitochondrial [KO:K02437]
122438399  glycine cleavage system H protein, mitochondrial [KO:K02437]
122441536  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122449970  glycine cleavage system H protein, mitochondrial [KO:K02437]
122452036  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122452278  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122453243  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122434906  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122434914  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122427182  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122428645  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
122437096  HYI; putative hydroxypyruvate isomerase isoform X1 [KO:K01816] [EC:5.3.1.22]
122424877  GLYCTK; glycerate kinase isoform X1 [KO:K11529] [EC:2.7.1.165]
122446094  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
122437460  AFMID; kynurenine formamidase isoform X1 [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ccad00010  Glycolysis / Gluconeogenesis
ccad00020  Citrate cycle (TCA cycle)
ccad00030  Pentose phosphate pathway
ccad00053  Ascorbate and aldarate metabolism
ccad00071  Fatty acid degradation
ccad00230  Purine metabolism
ccad00250  Alanine, aspartate and glutamate metabolism
ccad00260  Glycine, serine and threonine metabolism
ccad00620  Pyruvate metabolism
ccad00750  Vitamin B6 metabolism
ccad00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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