KEGG   PATHWAY: ccup00630
Entry
ccup00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cupriavidus sp. USMAHM13
Class
Metabolism; Carbohydrate metabolism
Pathway map
ccup00630  Glyoxylate and dicarboxylate metabolism
ccup00630

Module
ccup_M00012  Glyoxylate cycle [PATH:ccup00630]
ccup_M00621  Glycine cleavage system [PATH:ccup00630]
Other DBs
GO: 0046487 0043648
Organism
Cupriavidus sp. USMAHM13 [GN:ccup]
Gene
BKK81_22750  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BKK81_13180  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BKK81_19195  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
BKK81_31020  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
BKK81_08790  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
BKK81_14455  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BKK81_33765  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BKK81_13155  malate synthase A [KO:K01638] [EC:2.3.3.9]
BKK81_14955  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BKK81_27900  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
BKK81_14920  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BKK81_26305  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
BKK81_14965  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
BKK81_10135  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
BKK81_14980  aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
BKK81_24395  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
BKK81_03225  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_22170  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_29775  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_12500  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_12645  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_27235  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_11215  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_09950  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_18560  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_26115  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_30830  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK81_12640  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK81_26080  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK81_10175  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK81_11825  hypothetical protein [KO:K17865] [EC:4.2.1.55]
BKK81_12305  acetyl/propionyl-CoA carboxylase subuit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
BKK81_16860  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
BKK81_16870  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
BKK81_16875  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BKK81_03285  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK81_02610  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK81_20295  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK81_14740  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BKK81_14700  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
BKK81_17920  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BKK81_29025  hydrolase [KO:K01091] [EC:3.1.3.18]
BKK81_15765  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BKK81_01220  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
BKK81_01210  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
BKK81_13620  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK81_27150  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK81_12895  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK81_24835  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK81_01215  glycine cleavage system protein H [KO:K02437]
BKK81_01045  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BKK81_01050  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BKK81_01055  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK81_30345  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK81_16450  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK81_04760  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK81_01060  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK81_20270  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK81_04755  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK81_20915  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK81_31890  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK81_20260  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK81_30555  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BKK81_05805  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
BKK81_33890  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
BKK81_26660  formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
BKK81_26665  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
BKK81_05800  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
BKK81_26655  formate dehydrogenase subunit beta [KO:K00124]
BKK81_33885  NADH dehydrogenase [KO:K00124]
BKK81_05795  formate dehydrogenase [KO:K00124]
BKK81_26650  formate dehydrogenase subunit gamma [KO:K00127]
BKK81_05790  formate dehydrogenase subunit gamma [KO:K00127]
BKK81_31235  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
BKK81_15670  arylformamidase [KO:K07130] [EC:3.5.1.9]
BKK81_14345  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BKK81_22150  formamidase [KO:K01455] [EC:3.5.1.49]
BKK81_26505  formamidase [KO:K01455] [EC:3.5.1.49]
BKK81_02080  acetamidase [KO:K01455] [EC:3.5.1.49]
BKK81_16475  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ccup00010  Glycolysis / Gluconeogenesis
ccup00020  Citrate cycle (TCA cycle)
ccup00030  Pentose phosphate pathway
ccup00053  Ascorbate and aldarate metabolism
ccup00071  Fatty acid degradation
ccup00230  Purine metabolism
ccup00250  Alanine, aspartate and glutamate metabolism
ccup00260  Glycine, serine and threonine metabolism
ccup00620  Pyruvate metabolism
ccup00710  Carbon fixation by Calvin cycle
ccup00750  Vitamin B6 metabolism
ccup00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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