KEGG   PATHWAY: cld00230
Entry
cld00230                    Pathway                                
Name
Purine metabolism - Clostridium sporogenes
Class
Metabolism; Nucleotide metabolism
Pathway map
cld00230  Purine metabolism
cld00230

Module
cld_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cld00230]
cld_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cld00230]
cld_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cld00230]
cld_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cld00230]
Other DBs
GO: 0006163 0042278
Organism
Clostridium sporogenes [GN:cld]
Gene
CLSPO_c05080  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CLSPO_c18610  nudF; ADP-ribose pyrophosphatase NudF [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CLSPO_c20820  putative mutase [KO:K01839] [EC:5.4.2.7]
CLSPO_c38130  pgcA2; phosphoglucomutase PgcA [KO:K01835] [EC:5.4.2.2]
CLSPO_c32100  pgcA1; phosphoglucomutase PgcA [KO:K01835] [EC:5.4.2.2]
CLSPO_c37270  prs; ribose-phosphate pyrophosphokinase Prs [KO:K00948] [EC:2.7.6.1]
CLSPO_c29500  purF1; amidophosphoribosyltransferase PurF [KO:K00764] [EC:2.4.2.14]
CLSPO_c29830  purF2; amidophosphoribosyltransferase PurF [KO:K00764] [EC:2.4.2.14]
CLSPO_c29460  purD; phosphoribosylamine--glycine ligase PurD [KO:K01945] [EC:6.3.4.13]
CLSPO_c29480  purN; phosphoribosylglycinamide formyltransferase PurN [KO:K11175] [EC:2.1.2.2]
CLSPO_c26640  purL; phosphoribosylformylglycinamidine synthase 2 [KO:K01952] [EC:6.3.5.3]
CLSPO_c29490  purM; phosphoribosylformylglycinamidine cyclo-ligase PurM [KO:K01933] [EC:6.3.3.1]
CLSPO_c29520  purE; N5-carboxyaminoimidazole ribonucleotide mutase PurE [KO:K01588] [EC:5.4.99.18]
CLSPO_c29510  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase PurC [KO:K01923] [EC:6.3.2.6]
CLSPO_c24950  purB; adenylosuccinate lyase PurB [KO:K01756] [EC:4.3.2.2]
CLSPO_c29470  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CLSPO_c31540  apt; adenine phosphoribosyltransferase Apt [KO:K00759] [EC:2.4.2.7]
CLSPO_c20130  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CLSPO_c02650  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
CLSPO_c18570  punA; purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
CLSPO_c32840  hypothetical protein UPF0345 [KO:K09913] [EC:2.4.2.1 2.4.2.2]
CLSPO_c26240  laccase domain-containing protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CLSPO_c37020  hpt2; hypoxanthine-guanine phosphoribosyltransferase Hpt [KO:K00760] [EC:2.4.2.8]
CLSPO_c31750  hpt1; hypoxanthine-guanine phosphoribosyltransferase Hpt [KO:K00760] [EC:2.4.2.8]
CLSPO_c34160  guaB; inosine-5'-monophosphate dehydrogenase GuaB [KO:K00088] [EC:1.1.1.205]
CLSPO_c33830  Non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CLSPO_c03480  xpt1; xanthine phosphoribosyltransferase 1 [KO:K03816] [EC:2.4.2.22]
CLSPO_c11460  xpt2; xanthine phosphoribosyltransferase 2 [KO:K03816] [EC:2.4.2.22]
CLSPO_c12940  xdhA; xanthine dehydrogenase molybdenum-binding subunit [KO:K00087] [EC:1.17.1.4]
CLSPO_c12950  xdhB; xanthine dehydrogenase FAD-binding subunit [KO:K13479] [EC:1.17.1.4]
CLSPO_c12960  xdhC; xanthine dehydrogenase iron-sulfur-binding subunit [KO:K13480]
CLSPO_c34150  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
CLSPO_c12970  guaD; guanine deaminase GuaD [KO:K01487] [EC:3.5.4.3]
CLSPO_c26080  gmk; guanylate kinase Gmk [KO:K00942] [EC:2.7.4.8]
CLSPO_c28880  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CLSPO_c28870  nrdB; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CLSPO_c01200  nrdD; anaerobic ribonucleoside-triphosphate reductase NrdD [KO:K21636] [EC:1.1.98.6]
CLSPO_c30300  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
CLSPO_c31530  relA; GTP pyrophosphokinase RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CLSPO_c02170  RelA/SpoT domain-containing protein [KO:K07816] [EC:2.7.6.5]
CLSPO_c02240  cyaB; putative adenylyl cyclase CyaB [KO:K05873] [EC:4.6.1.1]
CLSPO_c38100  purA; adenylosuccinate synthetase PurA [KO:K01939] [EC:6.3.4.4]
CLSPO_c09910  add; adenosine deaminase Add [KO:K01488] [EC:3.5.4.4]
CLSPO_c03220  ade; adenine deaminase Ade [KO:K01486] [EC:3.5.4.2]
CLSPO_c36220  adk; adenylate kinase Adk [KO:K00939] [EC:2.7.4.3]
CLSPO_c29660  putative nucleotide kinase [KO:K06928] [EC:3.6.1.15]
CLSPO_c26660  arcC; carbamate kinase ArcC [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cld00030  Pentose phosphate pathway
cld00220  Arginine biosynthesis
cld00250  Alanine, aspartate and glutamate metabolism
cld00260  Glycine, serine and threonine metabolism
cld00340  Histidine metabolism
cld00630  Glyoxylate and dicarboxylate metabolism
cld00730  Thiamine metabolism
cld00740  Riboflavin metabolism
cld00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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