KEGG   PATHWAY: cmt00564
Entry
cmt00564                    Pathway                                
Name
Glycerophospholipid metabolism - Cordyceps militaris
Class
Metabolism; Lipid metabolism
Pathway map
cmt00564  Glycerophospholipid metabolism
cmt00564

Module
cmt_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:cmt00564]
cmt_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:cmt00564]
cmt_M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:cmt00564]
Other DBs
GO: 0006650
Organism
Cordyceps militaris [GN:cmt]
Gene
CCM_03540  glycerol-3-phosphate dehydrogenase [KO:K00006] [EC:1.1.1.8]
CCM_07439  glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
CCM_01734  glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
CCM_05062  glycerol-3-phosphate O-acyltransferase [KO:K13507] [EC:2.3.1.15 2.3.1.42]
CCM_02787  AtaAp protein [KO:K13509] [EC:2.3.1.51]
CCM_05827  MBOAT family protein [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
CCM_08202  Patatin family phospholipase, putative [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
CCM_03720  Phospholipid/glycerol acyltransferase [KO:K22831] [EC:2.3.1.51]
CCM_06840  short chain dehydrogenase/reductase, putative [KO:K06123] [EC:1.1.1.101]
CCM_00856  short chain dehydrogenase/reductase [KO:K06123] [EC:1.1.1.101]
CCM_05427  nuclear elongation and deformation protein 1 [KO:K15728] [EC:3.1.3.4]
CCM_07138  phosphatidic acid phosphatase beta [KO:K18693] [EC:3.6.1.75 3.1.3.4]
CCM_01708  PAP2 domain protein [KO:K18693] [EC:3.6.1.75 3.1.3.4]
CCM_00191  phosphatidate cytidylyltransferase, putative [KO:K16368] [EC:2.7.1.174]
CCM_04826  phosphoesterase superfamily protein [KO:K01114] [EC:3.1.4.3]
CCM_08292  non-hemolytic phospholipase C precursor, putative [KO:K01114] [EC:3.1.4.3]
CCM_08305  non-hemolytic phospholipase C precursor, putative [KO:K01114] [EC:3.1.4.3]
CCM_08323  non-hemolytic phospholipase C precursor, putative [KO:K01114] [EC:3.1.4.3]
CCM_00521  glycerophosphoryl diester phosphodiesterase, putative [KO:K18694] [EC:3.1.4.-]
CCM_00524  phospholipase D1 [KO:K01115] [EC:3.1.4.4]
CCM_04322  phospholipase D [KO:K01115] [EC:3.1.4.4]
CCM_02988  phospholipase PldA, putative [KO:K01115] [EC:3.1.4.4]
CCM_02980  cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
CCM_01743  lysophospholipase Plb1 [KO:K13333] [EC:3.1.1.5]
CCM_02898  lysophospholipase precursor [KO:K13333] [EC:3.1.1.5]
CCM_04741  Patatin-like serine hydrolase [KO:K14676] [EC:3.1.1.5]
CCM_08480  ankyrin repeat-containing protein, putative [KO:K18695] [EC:3.1.4.2]
CCM_05136  glycerophosphodiester phosphodiesterase GDE1 [KO:K18696] [EC:3.1.4.46]
CCM_06073  glycerophosphoryl diester phosphodiesterase family protein [KO:K01126] [EC:3.1.4.46]
CCM_00456  triacylglycerol lipase, putative [KO:K01049] [EC:3.1.1.7]
CCM_01895  para-nitrobenzyl esterase [KO:K01049] [EC:3.1.1.7]
CCM_04857  choline kinase [KO:K00866] [EC:2.7.1.32]
CCM_08417  cholinephosphate cytidylyltransferase [KO:K00968] [EC:2.7.7.15]
CCM_07652  sn-1,2-diacylglycerol cholinephosphotransferase [KO:K00993] [EC:2.7.8.1]
CCM_03250  ethanolaminephosphotransferase [KO:K00993] [EC:2.7.8.1]
CCM_01118  ethanolamine kinase, putative [KO:K00894] [EC:2.7.1.82]
CCM_09577  Rossmann-like alpha/beta/alpha sandwich fold domain containing protein [KO:K00967] [EC:2.7.7.14]
CCM_04620  phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
CCM_04704  Phosphatidylethanolamine N-methyltransferase, fungi [KO:K16369] [EC:2.1.1.17]
CCM_01859  phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
CCM_01247  phosphatidylserine synthase [KO:K17103] [EC:2.7.8.8]
CCM_06063  phosphatidylserine decarboxylase family protein [KO:K01613] [EC:4.1.1.65]
CCM_07932  phosphatidylserine decarboxylase family protein [KO:K01613] [EC:4.1.1.65]
CCM_08421  phosphatidylserine decarboxylase Psd2, putative [KO:K01613] [EC:4.1.1.65]
CCM_09213  phosphatidylserine decarboxylase family protein [KO:K01613] [EC:4.1.1.65]
CCM_05648  phosphatidylserine decarboxylase proenzyme 1 [KO:K01613] [EC:4.1.1.65]
CCM_09410  CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]
CCM_07712  hypothetical protein [KO:K01094] [EC:3.1.3.27]
CCM_05831  phosphatidyl synthase [KO:K08744] [EC:2.7.8.41]
CCM_05795  tafazzin [KO:K13511] [EC:2.3.1.-]
CCM_04700  alpha/beta hydrolase, putative [KO:K13535] [EC:3.1.1.-]
CCM_05258  CDP-diacylglycerol-inositol 3-phosphatidyltransferase PIS [KO:K00999] [EC:2.7.8.11]
CCM_00098  Methyltransferase type 11 [KO:K13621]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
cmt00010  Glycolysis / Gluconeogenesis
cmt00260  Glycine, serine and threonine metabolism
cmt00561  Glycerolipid metabolism
cmt00562  Inositol phosphate metabolism
cmt00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
cmt00565  Ether lipid metabolism
cmt00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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