KEGG   PATHWAY: cuu00630
Entry
cuu00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cupriavidus sp. USMAA2-4
Class
Metabolism; Carbohydrate metabolism
Pathway map
cuu00630  Glyoxylate and dicarboxylate metabolism
cuu00630

Module
cuu_M00012  Glyoxylate cycle [PATH:cuu00630]
cuu_M00621  Glycine cleavage system [PATH:cuu00630]
Other DBs
GO: 0046487 0043648
Organism
Cupriavidus sp. USMAA2-4 [GN:cuu]
Gene
BKK79_24445  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BKK79_18890  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
BKK79_04040  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
BKK79_31040  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
BKK79_17545  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BKK79_28020  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
BKK79_18915  malate synthase A [KO:K01638] [EC:2.3.3.9]
BKK79_17045  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BKK79_21195  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
BKK79_20660  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
BKK79_34375  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
BKK79_17080  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BKK79_02555  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
BKK79_17035  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
BKK79_17020  aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
BKK79_22875  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
BKK79_19480  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_28715  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_01360  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_02720  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_24915  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_31400  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_09700  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_19440  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_20850  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_32465  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_35040  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BKK79_19445  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK79_20930  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK79_02515  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BKK79_14450  (R)-hydratase [KO:K17865] [EC:4.2.1.55]
BKK79_00400  hypothetical protein [KO:K17865] [EC:4.2.1.55]
BKK79_19685  acetyl/propionyl-CoA carboxylase subuit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
BKK79_14200  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
BKK79_14190  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
BKK79_14185  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BKK79_09640  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK79_10320  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK79_26705  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BKK79_17260  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BKK79_33250  hydrolase [KO:K01091] [EC:3.1.3.18]
BKK79_17300  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
BKK79_13240  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BKK79_16235  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BKK79_11605  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
BKK79_11615  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
BKK79_22415  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK79_19185  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK79_18450  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK79_35125  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BKK79_11610  glycine cleavage system protein H [KO:K02437]
BKK79_11775  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BKK79_11770  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BKK79_31885  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK79_11765  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK79_14890  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BKK79_08160  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK79_11760  glycerate kinase [KO:K11529] [EC:2.7.1.165]
BKK79_29735  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK79_08165  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK79_26180  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BKK79_31675  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BKK79_07170  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
BKK79_35605  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
BKK79_35610  formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
BKK79_07175  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
BKK79_07180  formate dehydrogenase [KO:K00124]
BKK79_35615  formate dehydrogenase subunit beta [KO:K00124]
BKK79_07185  formate dehydrogenase subunit gamma [KO:K00127]
BKK79_35620  formate dehydrogenase subunit gamma [KO:K00127]
BKK79_30810  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
BKK79_16330  arylformamidase [KO:K07130] [EC:3.5.1.9]
BKK79_17725  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BKK79_20460  formamidase [KO:K01455] [EC:3.5.1.49]
BKK79_24935  formamidase [KO:K01455] [EC:3.5.1.49]
BKK79_10795  acetamidase [KO:K01455] [EC:3.5.1.49]
BKK79_14865  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cuu00010  Glycolysis / Gluconeogenesis
cuu00020  Citrate cycle (TCA cycle)
cuu00030  Pentose phosphate pathway
cuu00053  Ascorbate and aldarate metabolism
cuu00071  Fatty acid degradation
cuu00230  Purine metabolism
cuu00250  Alanine, aspartate and glutamate metabolism
cuu00260  Glycine, serine and threonine metabolism
cuu00620  Pyruvate metabolism
cuu00710  Carbon fixation by Calvin cycle
cuu00750  Vitamin B6 metabolism
cuu00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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