KEGG   PATHWAY: dml00630
Entry
dml00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Desulfococcus multivorans
Class
Metabolism; Carbohydrate metabolism
Pathway map
dml00630  Glyoxylate and dicarboxylate metabolism
dml00630

Module
dml_M00012  Glyoxylate cycle [PATH:dml00630]
dml_M00621  Glycine cleavage system [PATH:dml00630]
dml_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:dml00630]
Other DBs
GO: 0046487 0043648
Organism
Desulfococcus multivorans [GN:dml]
Gene
Dmul_36570  aceA; AceA: isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Dmul_23620  acsA5; AcsA5: acetyl-coenzyme A synthetase (acetate--CoA ligase) [KO:K01895] [EC:6.2.1.1]
Dmul_19320  acsA3; AcsA3: acetyl-coenzyme A synthetase (acetate--CoA ligase) [KO:K01895] [EC:6.2.1.1]
Dmul_21830  acsA4; AcsA4: acetyl-coenzyme A synthetase (acetate--CoA ligase) [KO:K01895] [EC:6.2.1.1]
Dmul_36580  mls; Mls: malate synthase [KO:K01638] [EC:2.3.3.9]
Dmul_21750  mdh; Mdh: malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Dmul_35200  gltA2; GltA2: citrate synthase [KO:K01647] [EC:2.3.3.1]
Dmul_31220  gltA1; GltA1: citrate synthase, type II [KO:K01647] [EC:2.3.3.1]
Dmul_10470  acnA; AcnA: aconitate hydratase (aconitase) [KO:K01681] [EC:4.2.1.3]
Dmul_30450  thlA; ThlA: acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Dmul_00850  atoB1; AtoB1: acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase) [KO:K00626] [EC:2.3.1.9]
Dmul_11540  atoB2; AtoB2: acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase) [KO:K00626] [EC:2.3.1.9]
Dmul_24960  thiolase, C-terminal domain protein [KO:K00626] [EC:2.3.1.9]
Dmul_03570  thlA; ThlA: acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Dmul_24650  thiolase [KO:K00626] [EC:2.3.1.9]
Dmul_24750  thiolase [KO:K00626] [EC:2.3.1.9]
Dmul_05700  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
Dmul_35980  maoC; MaoC: dehydratase, MaoC family [KO:K17865] [EC:4.2.1.55]
Dmul_24350  putative methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Dmul_34090  mce; Mce: methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Dmul_11170  citrate lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Dmul_09710  accA; AccA: propionyl-CoA carboxylase, subunit alpha [KO:K01965] [EC:6.4.1.3]
Dmul_03480  pccB1; PccB1: propionyl-CoA carboxylase, subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Dmul_09720  pccB2; PccB2: propionyl-CoA carboxylase, subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Dmul_34100  sbm; Sbm: methylmalonyl-CoA mutase-like [KO:K01847] [EC:5.4.99.2]
Dmul_17500  ldhA; LdhA: lactate dehydrogenase, subunit alpha [KO:K00104] [EC:1.1.99.14]
Dmul_17490  ldhB; LdhB: lactate dehydrogenase, subunit beta [KO:K11473] [EC:1.1.99.14]
Dmul_35920  katA; KatA: catalase [KO:K03781] [EC:1.11.1.6]
Dmul_00130  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Dmul_38210  glnA; GlnA: glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Dmul_15510  glyA; GlyA: serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Dmul_38430  gcvPA; GcvPA: glycine dehydrogenase (decarboxylating), glycine cleavage system P protein, subunit 1 [KO:K00282] [EC:1.4.4.2]
Dmul_38440  gcvPB; GcvPB: glycine dehydrogenase (decarboxylating), glycine cleavage system P protein, subunit 2 [KO:K00283] [EC:1.4.4.2]
Dmul_38410  gcvT; GcvT: glycine cleavage system, T protein [KO:K00605] [EC:2.1.2.10]
Dmul_34830  lpdA2; LpdA2: dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex) [KO:K00382] [EC:1.8.1.4]
Dmul_20930  lpdA1; LpdA1: dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex) [KO:K00382] [EC:1.8.1.4]
Dmul_38420  gcvH; GcvH: glycine cleavage system, H protein [KO:K02437]
Dmul_30080  hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Dmul_34240  morA; MorA: molybdopterin oxidoreductase [KO:K00123] [EC:1.17.1.9]
Dmul_08110  hmcB; HmcB: HMC redox complex, transmembrane protein [KO:K00124]
Dmul_38150  4Fe-4S ferredoxin iron-sulfur binding domain protein [KO:K00124]
Dmul_35960  putative transmembrane di-heme cytochrome [KO:K00127]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
dml00010  Glycolysis / Gluconeogenesis
dml00020  Citrate cycle (TCA cycle)
dml00030  Pentose phosphate pathway
dml00053  Ascorbate and aldarate metabolism
dml00071  Fatty acid degradation
dml00230  Purine metabolism
dml00250  Alanine, aspartate and glutamate metabolism
dml00260  Glycine, serine and threonine metabolism
dml00620  Pyruvate metabolism
dml00710  Carbon fixation by Calvin cycle
dml00750  Vitamin B6 metabolism
dml00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system