KEGG   PATHWAY: ecx00630
Entry
ecx00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O9 HS (commensal)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ecx00630  Glyoxylate and dicarboxylate metabolism
ecx00630

Module
ecx_M00012  Glyoxylate cycle [PATH:ecx00630]
ecx_M00621  Glycine cleavage system [PATH:ecx00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O9 HS (commensal) [GN:ecx]
Gene
EcHS_A4249  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
EcHS_A4314  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
EcHS_A4248  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
EcHS_A3148  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
EcHS_A3425  mdh; malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
EcHS_A0768  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
EcHS_A0825  aconitase family protein [KO:K01681] [EC:4.2.1.3]
EcHS_A1387  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
EcHS_A0122  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
EcHS_A2365  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EcHS_A2991  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EcHS_A3075  msm; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
EcHS_A3152  glcD; glycolate oxidase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
EcHS_A3151  glcE; glycolate oxidase, subunit GlcE [KO:K11472] [EC:1.1.99.14]
EcHS_A3150  glcF; glycolate oxidase, iron-sulfur subunit GlcF [KO:K11473] [EC:1.1.99.14]
EcHS_A1813  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
EcHS_A1151  D-isomer specific 2-hydroxyacid dehydrogenase family protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
EcHS_A3754  tkrA; 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
EcHS_A3581  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
EcHS_A4097  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EcHS_A2704  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EcHS_A3062  gcvP; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
EcHS_A3064  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
EcHS_A0120  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
EcHS_A3063  gcvH; glycine cleavage system H protein [KO:K02437]
EcHS_A0581  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
EcHS_A0582  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
EcHS_A0583  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EcHS_A3314  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EcHS_A3313  garK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
EcHS_A0587  glycerate kinase [KO:K00865] [EC:2.7.1.165]
EcHS_A1498  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
EcHS_A2943  fucO; lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
EcHS_A3241  ddtA; L(+)-tartrate dehydratase, alpha subunit [KO:K03779] [EC:4.2.1.32]
EcHS_A3242  ttdB; L(+)-tartrate dehydratase, beta subunit [KO:K03780] [EC:4.2.1.32]
EcHS_A1888  ttuC; tartrate dehydrogenase/decarboxylase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
EcHS_A1942  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EcHS_A4122  fdoG; formate dehydrogenase-O, major subunit, selenocysteine-containing [KO:K00123] [EC:1.17.1.9]
EcHS_A4121  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
EcHS_A4120  fdoI; formate dehydrogenase-O, gamma subunit [KO:K00127]
EcHS_A1340  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
EcHS_A2510  thiamine pyrophosphate-dependent enzyme [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ecx00010  Glycolysis / Gluconeogenesis
ecx00020  Citrate cycle (TCA cycle)
ecx00030  Pentose phosphate pathway
ecx00053  Ascorbate and aldarate metabolism
ecx00071  Fatty acid degradation
ecx00230  Purine metabolism
ecx00250  Alanine, aspartate and glutamate metabolism
ecx00260  Glycine, serine and threonine metabolism
ecx00620  Pyruvate metabolism
ecx00710  Carbon fixation by Calvin cycle
ecx00750  Vitamin B6 metabolism
ecx00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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