KEGG   PATHWAY: ekf00630
Entry
ekf00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli KO11FL
Class
Metabolism; Carbohydrate metabolism
Pathway map
ekf00630  Glyoxylate and dicarboxylate metabolism
ekf00630

Module
ekf_M00012  Glyoxylate cycle [PATH:ekf00630]
ekf_M00621  Glycine cleavage system [PATH:ekf00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli KO11FL [GN:ekf]
Gene
KO11_02320  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
KO11_02020  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
KO11_02325  aceB; malate synthase [KO:K01638] [EC:2.3.3.9]
KO11_07835  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
KO11_06520  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
KO11_20150  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
KO11_19925  ybhJ; putative hydratase [KO:K01681] [EC:4.2.1.3]
KO11_16440  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
KO11_00565  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
KO11_08585  yqeF; putative acyltransferase [KO:K00626] [EC:2.3.1.9]
KO11_08185  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
KO11_07815  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
KO11_07820  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
KO11_07825  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
KO11_14075  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
KO11_17565  ghrA; bifunctional glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KO11_04960  ghrB; bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
KO11_05875  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
KO11_04355  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
KO11_10065  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KO11_08250  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
KO11_08240  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
KO11_00555  lpd; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
KO11_08245  gcvH; glycine cleavage system protein H [KO:K02437]
KO11_21050  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
KO11_21045  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
KO11_21040  glxR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
KO11_07050  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
KO11_07055  garK; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
KO11_21020  glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
KO11_15310  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
KO11_08960  fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
KO11_07410  ttdA; tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
KO11_07405  ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
KO11_13715  dmlA; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KO11_13455  eda; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
KO11_03110  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
KO11_03115  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
KO11_03120  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
KO11_03125  fdoI; formate dehydrogenase-O subunit gamma [KO:K00127]
KO11_16655  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
KO11_10895  oxc; putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ekf00010  Glycolysis / Gluconeogenesis
ekf00020  Citrate cycle (TCA cycle)
ekf00030  Pentose phosphate pathway
ekf00053  Ascorbate and aldarate metabolism
ekf00071  Fatty acid degradation
ekf00230  Purine metabolism
ekf00250  Alanine, aspartate and glutamate metabolism
ekf00260  Glycine, serine and threonine metabolism
ekf00620  Pyruvate metabolism
ekf00710  Carbon fixation by Calvin cycle
ekf00750  Vitamin B6 metabolism
ekf00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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