KEGG   PATHWAY: esm00630
Entry
esm00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O104:H4 2009EL-2050 (EAEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
esm00630  Glyoxylate and dicarboxylate metabolism
esm00630

Module
esm_M00012  Glyoxylate cycle [PATH:esm00630]
esm_M00621  Glycine cleavage system [PATH:esm00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O104:H4 2009EL-2050 (EAEC) [GN:esm]
Gene
O3M_23725  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
O3M_23425  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
O3M_04115  malate synthase G [KO:K01638] [EC:2.3.3.9]
O3M_23730  malate synthase [KO:K01638] [EC:2.3.3.9]
O3M_02830  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
O3M_18025  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
O3M_13935  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
O3M_17795  putative hydratase [KO:K01681] [EC:4.2.1.3]
O3M_20875  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
O3M_05335  putative acyltransferase [KO:K00626] [EC:2.3.1.9]
O3M_04930  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
O3M_04935  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
O3M_04095  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
O3M_04100  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
O3M_04105  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
O3M_11285  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
O3M_15365  ghrA; bifunctional glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
O3M_01125  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
O3M_02190  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
O3M_24450  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
O3M_06705  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
O3M_04995  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
O3M_04985  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
O3M_20885  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
O3M_04990  glycine cleavage system protein H [KO:K02437]
O3M_18935  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
O3M_18930  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
O3M_18925  tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
O3M_03360  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
O3M_03365  glycerate kinase I [KO:K00865] [EC:2.7.1.165]
O3M_18905  glycerate kinase II [KO:K00865] [EC:2.7.1.165]
O3M_13385  aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
O3M_05545  L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
O3M_03685  tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
O3M_03680  L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
O3M_10920  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
O3M_10660  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
O3M_24315  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
O3M_24320  formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
O3M_24325  formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
O3M_24330  formate dehydrogenase-O subunit gamma [KO:K00127]
O3M_14470  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
O3M_07555  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
esm00010  Glycolysis / Gluconeogenesis
esm00020  Citrate cycle (TCA cycle)
esm00030  Pentose phosphate pathway
esm00053  Ascorbate and aldarate metabolism
esm00071  Fatty acid degradation
esm00230  Purine metabolism
esm00250  Alanine, aspartate and glutamate metabolism
esm00260  Glycine, serine and threonine metabolism
esm00620  Pyruvate metabolism
esm00710  Carbon fixation by Calvin cycle
esm00750  Vitamin B6 metabolism
esm00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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