KEGG   PATHWAY: ftx00620
Entry
ftx00620                    Pathway                                
Name
Pyruvate metabolism - Francisella tularensis subsp. novicida U112
Class
Metabolism; Carbohydrate metabolism
Pathway map
ftx00620  Pyruvate metabolism
ftx00620

Module
ftx_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ftx00620]
ftx_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ftx00620]
Other DBs
GO: 0006090
Organism
Francisella tularensis subsp. novicida U112 [GN:ftx]
Gene
AW25_1291  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
AW25_507  aceE; pyruvate dehydrogenase (acetyl-transferring), homodimeric type [KO:K00163] [EC:1.2.4.1]
AW25_508  aceF; dihydrolipoyllysine-residue acetyltransferase [KO:K00627] [EC:2.3.1.12]
AW25_509  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
AW25_1625  S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
AW25_75  ackA; acetate kinase [KO:K00925] [EC:2.7.2.1]
AW25_74  pta; phosphate acetyltransferase [KO:K13788] [EC:2.3.1.8]
AW25_673  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
AW25_493  accA; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit [KO:K01962] [EC:6.4.1.2 2.1.3.15]
AW25_1466  accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein [KO:K02160]
AW25_1465  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
AW25_1771  accD; acetyl-CoA carboxylase, carboxyl transferase, beta subunit [KO:K01963] [EC:6.4.1.2 2.1.3.15]
AW25_1829  FMN-dependent dehydrogenase family protein [KO:K00101] [EC:1.1.2.3]
AW25_1020  IMP dehydrogenase / GMP reductase domain protein [KO:K00101] [EC:1.1.2.3]
AW25_229  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K03778] [EC:1.1.1.28]
AW25_1021  4Fe-4S dicluster domain protein [KO:K18930]
AW25_864  4Fe-4S dicluster domain protein [KO:K18930]
AW25_775  gloA; lactoylglutathione lyase [KO:K01759] [EC:4.4.1.5]
AW25_633  metallo-beta-lactamase superfamily protein [KO:K01069] [EC:3.1.2.6]
AW25_1591  malic enzyme, NAD binding domain protein [KO:K00027] [EC:1.1.1.38]
AW25_1032  mdh; malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
AW25_1703  hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein [KO:K01676] [EC:4.2.1.2]
AW25_1824  fumC; fumarate hydratase, class II [KO:K01679] [EC:4.2.1.2]
AW25_1489  phosphoenolpyruvate carboxykinase family protein [KO:K01610] [EC:4.1.1.49]
AW25_136  ppdK; pyruvate, phosphate dikinase [KO:K01006] [EC:2.7.9.1]
AW25_138  HMGL-like family protein [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
ftx00010  Glycolysis / Gluconeogenesis
ftx00020  Citrate cycle (TCA cycle)
ftx00061  Fatty acid biosynthesis
ftx00250  Alanine, aspartate and glutamate metabolism
ftx00260  Glycine, serine and threonine metabolism
ftx00290  Valine, leucine and isoleucine biosynthesis
ftx00300  Lysine biosynthesis
ftx00630  Glyoxylate and dicarboxylate metabolism
ftx00640  Propanoate metabolism
ftx00650  Butanoate metabolism
ftx00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   
LinkDB

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