KEGG   PATHWAY: ghi00062
Entry
ghi00062                    Pathway                                
Name
Fatty acid elongation - Gossypium hirsutum (upland cotton)
Class
Metabolism; Lipid metabolism
Pathway map
ghi00062  Fatty acid elongation
ghi00062

Module
ghi_M00415  Fatty acid elongation in endoplasmic reticulum [PATH:ghi00062]
Other DBs
GO: 0030497
Organism
Gossypium hirsutum (upland cotton) [GN:ghi]
Gene
107950314  enoyl-[acyl-carrier-protein] reductase, mitochondrial [KO:K07512] [EC:1.3.1.- 1.3.1.38]
121224237  enoyl-[acyl-carrier-protein] reductase, mitochondrial-like isoform X1 [KO:K07512] [EC:1.3.1.- 1.3.1.38]
107929689  palmitoyl-protein thioesterase 1 isoform X1 [KO:K01074] [EC:3.1.2.22]
107899896  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
107946928  palmitoyl-protein thioesterase 1 [KO:K01074] [EC:3.1.2.22]
107945558  palmitoyl-protein thioesterase 1 [KO:K01074] [EC:3.1.2.22]
107886055  palmitoyl-protein thioesterase 1 isoform X1 [KO:K01074] [EC:3.1.2.22]
107923947  palmitoyl-protein thioesterase 1 [KO:K01074] [EC:3.1.2.22]
107953001  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
107895836  3-ketoacyl-CoA synthase 19-like isoform X1 [KO:K15397] [EC:2.3.1.199]
107915006  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
107892085  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
107893385  3-ketoacyl-CoA synthase 10-like [KO:K15397] [EC:2.3.1.199]
107928537  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107959894  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107907251  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107927815  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
107928898  3-ketoacyl-CoA synthase 9 [KO:K15397] [EC:2.3.1.199]
107906172  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
107910371  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
107909579  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
107917594  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
107925982  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107933940  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
107922145  LOW QUALITY PROTEIN: 3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
107923297  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
107901193  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107907434  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107908784  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
107936954  3-ketoacyl-CoA synthase 9 [KO:K15397] [EC:2.3.1.199]
107941561  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107887123  LOW QUALITY PROTEIN: 3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
107954085  3-ketoacyl-CoA synthase 12-like precursor [KO:K15397] [EC:2.3.1.199]
107945886  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
107954422  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
107963574  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
107905432  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
107923876  3-ketoacyl-CoA synthase 5 [KO:K15397] [EC:2.3.1.199]
107910190  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
107929116  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107886641  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
107897760  3-ketoacyl-CoA synthase 20 [KO:K15397] [EC:2.3.1.199]
107897764  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107897788  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107897789  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107897791  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107960424  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
107891913  3-ketoacyl-CoA synthase 20 [KO:K15397] [EC:2.3.1.199]
107930666  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107930667  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107930681  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
107925445  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
121220002  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
121225180  3-ketoacyl-CoA synthase 10-like [KO:K15397] [EC:2.3.1.199]
121227211  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
107900476  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
107928804  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
107932934  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
107959078  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
107962642  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
107950155  very-long-chain 3-oxoacyl-CoA reductase 1-like [KO:K10251] [EC:1.1.1.62 1.1.1.330]
107950163  very-long-chain 3-oxoacyl-CoA reductase 1 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
107909730  very-long-chain 3-oxoacyl-CoA reductase 1 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
107886490  very-long-chain 3-oxoacyl-CoA reductase 1 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
107886000  very-long-chain 3-oxoacyl-CoA reductase 1 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
107886008  very-long-chain 3-oxoacyl-CoA reductase 1 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
107907878  very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
121203366  very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
107913394  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2 [KO:K10703] [EC:4.2.1.134]
107950284  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2-like [KO:K10703] [EC:4.2.1.134]
107963934  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 [KO:K10703] [EC:4.2.1.134]
121202797  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2-like [KO:K10703] [EC:4.2.1.134]
107904734  very-long-chain enoyl-CoA reductase [KO:K10258] [EC:1.3.1.93]
107959873  very-long-chain enoyl-CoA reductase-like [KO:K10258] [EC:1.3.1.93]
107934412  very-long-chain enoyl-CoA reductase [KO:K10258] [EC:1.3.1.93]
121207779  very-long-chain enoyl-CoA reductase [KO:K10258] [EC:1.3.1.93]
107923939  acyl-CoA thioesterase 2 [KO:K01068] [EC:3.1.2.2]
Compound
C00024  Acetyl-CoA
C00040  Acyl-CoA
C00083  Malonyl-CoA
C00136  Butanoyl-CoA
C00154  Palmitoyl-CoA
C00162  Fatty acid
C00249  Hexadecanoic acid
C00264  3-Oxoacyl-CoA
C00605  2,3-Dehydroacyl-CoA
C00638  Long-chain fatty acid
C00640  (3S)-3-Hydroxyacyl-CoA
C00658  trans-2,3-Dehydroacyl-CoA
C01832  Lauroyl-CoA
C01944  Octanoyl-CoA
C02593  Tetradecanoyl-CoA
C02843  Long-chain acyl-CoA
C03221  2-trans-Dodecenoyl-CoA
C05258  (S)-3-Hydroxyhexadecanoyl-CoA
C05259  3-Oxopalmitoyl-CoA
C05260  (S)-3-Hydroxytetradecanoyl-CoA
C05261  3-Oxotetradecanoyl-CoA
C05262  (S)-3-Hydroxydodecanoyl-CoA
C05263  3-Oxododecanoyl-CoA
C05264  (S)-Hydroxydecanoyl-CoA
C05265  3-Oxodecanoyl-CoA
C05266  (S)-3-Hydroxyoctanoyl-CoA
C05267  3-Oxooctanoyl-CoA
C05268  (S)-Hydroxyhexanoyl-CoA
C05269  3-Oxohexanoyl-CoA
C05270  Hexanoyl-CoA
C05271  trans-Hex-2-enoyl-CoA
C05272  trans-Hexadec-2-enoyl-CoA
C05273  trans-Tetradec-2-enoyl-CoA
C05274  Decanoyl-CoA
C05275  trans-Dec-2-enoyl-CoA
C05276  trans-Oct-2-enoyl-CoA
C20876  Very-long-chain acyl-CoA
C20877  Very-long-chain 3-oxoacyl-CoA
C20878  Very-long-chain (3R)-3-hydroxyacyl-CoA
C20879  Very-long-chain trans-2,3-dehydroacyl-CoA
Reference
PMID:4387390
  Authors
Seubert W, Lamberts I, Kramer R, Ohly B
  Title
On the mechanism of malonyl-CoA-independent fatty acid synthesis. I. The mechanism of elongation of long-chain fatty acids by acetyl-CoA.
  Journal
Biochim Biophys Acta 164:498-517 (1968)
DOI:10.1016/0005-2760(68)90180-X
Reference
PMID:7150615
  Authors
El-Fakhri M, Middleton B
  Title
The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria.
  Journal
Biochim Biophys Acta 713:270-9 (1982)
DOI:10.1016/0005-2760(82)90244-2
Reference
PMID:8190743
  Authors
Cassagne C, Lessire R, Bessoule JJ, Moreau P, Creach A, Schneider F, Sturbois B
  Title
Biosynthesis of very long chain fatty acids in higher plants.
  Journal
Prog Lipid Res 33:55-69 (1994)
DOI:10.1016/0163-7827(94)90009-4
Reference
PMID:16564093
  Authors
Jakobsson A, Westerberg R, Jacobsson A.
  Title
Fatty acid elongases in mammals: their regulation and roles in metabolism.
  Journal
Prog Lipid Res 45:237-49 (2006)
DOI:10.1016/j.plipres.2006.01.004
Reference
PMID:16765910
  Authors
Blacklock BJ, Jaworski JG
  Title
Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.
  Journal
Biochem Biophys Res Commun 346:583-90 (2006)
DOI:10.1016/j.bbrc.2006.05.162
Reference
PMID:16866954
  Authors
Shepherd T, Wynne Griffiths D
  Title
The effects of stress on plant cuticular waxes.
  Journal
New Phytol 171:469-99 (2006)
DOI:10.1111/j.1469-8137.2006.01826.x
Reference
PMID:17719534
  Authors
Riezman H
  Title
The long and short of fatty acid synthesis.
  Journal
Cell 130:587-8 (2007)
DOI:10.1016/j.cell.2007.08.008
Reference
PMID:19649180
  Authors
Raffaele S, Leger A, Roby D
  Title
Very long chain fatty acid and lipid signaling in the response of plants to pathogens.
  Journal
Plant Signal Behav 4:94-9 (2009)
DOI:10.4161/psb.4.2.7580
Related
pathway
ghi00071  Fatty acid degradation
ghi00073  Cutin, suberine and wax biosynthesis
KO pathway
ko00062   
LinkDB

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