KEGG   PATHWAY: goi00630
Entry
goi00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Gordonia otitidis
Class
Metabolism; Carbohydrate metabolism
Pathway map
goi00630  Glyoxylate and dicarboxylate metabolism
goi00630

Module
goi_M00012  Glyoxylate cycle [PATH:goi00630]
goi_M00621  Glycine cleavage system [PATH:goi00630]
goi_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:goi00630]
Other DBs
GO: 0046487 0043648
Organism
Gordonia otitidis [GN:goi]
Gene
LK459_05895  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
LK459_06675  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
LK459_08700  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
LK459_20490  malate synthase G [KO:K01638] [EC:2.3.3.9]
LK459_20435  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
LK459_01615  bifunctional 2-methylcitrate synthase/citrate synthase [KO:K01647] [EC:2.3.3.1]
LK459_04230  citrate synthase [KO:K01647] [EC:2.3.3.1]
LK459_04305  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
LK459_10515  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
LK459_10520  citrate synthase [KO:K01647] [EC:2.3.3.1]
LK459_21820  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
LK459_00930  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_02595  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_04120  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_04700  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_10870  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_11070  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_13640  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_13795  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
LK459_13825  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
LK459_15280  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
LK459_00935  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
LK459_01545  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
LK459_01515  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
LK459_01520  acyl-CoA carboxylase subunit epsilon [KO:K27095]
LK459_18885  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
LK459_21740  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
LK459_21745  methylmalonyl-CoA mutase family protein [KO:K01847] [EC:5.4.99.2]
LK459_12035  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
LK459_11890  catalase [KO:K03781] [EC:1.11.1.6]
LK459_19000  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
LK459_04005  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
LK459_09075  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LK459_19070  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LK459_19115  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LK459_02385  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LK459_20480  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
LK459_19160  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
LK459_05940  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LK459_20455  gcvH; glycine cleavage system protein GcvH [KO:K02437]
LK459_19885  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
LK459_19185  glycerate kinase [KO:K00865] [EC:2.7.1.165]
LK459_01255  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
LK459_04660  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
LK459_04655  4Fe-4S dicluster domain-containing protein [KO:K00124]
LK459_05800  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
LK459_08495  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
LK459_01355  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
goi00010  Glycolysis / Gluconeogenesis
goi00020  Citrate cycle (TCA cycle)
goi00030  Pentose phosphate pathway
goi00053  Ascorbate and aldarate metabolism
goi00071  Fatty acid degradation
goi00230  Purine metabolism
goi00250  Alanine, aspartate and glutamate metabolism
goi00260  Glycine, serine and threonine metabolism
goi00620  Pyruvate metabolism
goi00710  Carbon fixation by Calvin cycle
goi00750  Vitamin B6 metabolism
goi00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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