KEGG   PATHWAY: hco00630
Entry
hco00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halomonas chromatireducens
Class
Metabolism; Carbohydrate metabolism
Pathway map
hco00630  Glyoxylate and dicarboxylate metabolism
hco00630

Module
hco_M00012  Glyoxylate cycle [PATH:hco00630]
hco_M00621  Glycine cleavage system [PATH:hco00630]
Other DBs
GO: 0046487 0043648
Organism
Halomonas chromatireducens [GN:hco]
Gene
LOKO_02690  Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
LOKO_00526  acsA_1; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
LOKO_00652  acsA_2; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
LOKO_03530  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
LOKO_00699  mdh_1; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
LOKO_03057  gltA; Citrate synthase [KO:K01647] [EC:2.3.3.1]
LOKO_02858  prpC; 2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
LOKO_02994  acnA_2; Aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
LOKO_02012  acnB; Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
LOKO_02577  thlA_1; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
LOKO_03382  pcaF_2; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
LOKO_03413  thlA_2; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
LOKO_03638  bktB; Beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
LOKO_03295  phbB; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
LOKO_03571  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
LOKO_03572  putative FAD-linked oxidoreductase [KO:K11472] [EC:1.1.99.14]
LOKO_03573  lutA_2; Lactate utilization protein A [KO:K11473] [EC:1.1.99.14]
LOKO_02703  katE; Catalase HPII [KO:K03781] [EC:1.11.1.6]
LOKO_00476  ghrA; Glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
LOKO_01848  Putative 2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
LOKO_00898  gph_1; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
LOKO_01191  gph_2; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
LOKO_03562  Soluble hydrogenase 42 kDa subunit [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
LOKO_00022  glnA_1; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
LOKO_01143  puuA_1; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
LOKO_03033  glnA_2; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
LOKO_02564  puuA_2; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
LOKO_00388  glyA2_1; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
LOKO_00727  glyA2_2; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
LOKO_00437  gcvP; Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
LOKO_00440  gcvT_1; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
LOKO_01551  lpdA_1; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LOKO_02798  lpd; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LOKO_00438  gcvH; Glycine cleavage system H protein [KO:K02437]
LOKO_01829  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
LOKO_01828  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
LOKO_01826  ttuD; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
LOKO_03591  dmlA; D-malate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
LOKO_02321  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LOKO_00462  Putative formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
LOKO_00461  nqo1; NADH-quinone oxidoreductase chain 1 [KO:K22515] [EC:1.17.1.9]
LOKO_00764  lip2; Lipase 2 [KO:K01432] [EC:3.5.1.9]
LOKO_00531  purU_1; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
LOKO_02041  purU_2; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hco00010  Glycolysis / Gluconeogenesis
hco00020  Citrate cycle (TCA cycle)
hco00030  Pentose phosphate pathway
hco00053  Ascorbate and aldarate metabolism
hco00071  Fatty acid degradation
hco00230  Purine metabolism
hco00250  Alanine, aspartate and glutamate metabolism
hco00260  Glycine, serine and threonine metabolism
hco00620  Pyruvate metabolism
hco00710  Carbon fixation by Calvin cycle
hco00750  Vitamin B6 metabolism
hco00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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