KEGG   PATHWAY: hhip00630
Entry
hhip00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Hippoglossus hippoglossus (Atlantic halibut)
Class
Metabolism; Carbohydrate metabolism
Pathway map
hhip00630  Glyoxylate and dicarboxylate metabolism
hhip00630

Module
hhip_M00621  Glycine cleavage system [PATH:hhip00630]
hhip_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hhip00630]
Other DBs
GO: 0046487 0043648
Organism
Hippoglossus hippoglossus (Atlantic halibut) [GN:hhip]
Gene
117775434  LOW QUALITY PROTEIN: acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
117758164  acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
117777651  acss2l; acyl-CoA synthetase short chain family member 2 like [KO:K01895] [EC:6.2.1.1]
117764995  acss2; acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
117775280  mdh1ab; malate dehydrogenase 1Ab, NAD (soluble) [KO:K00025] [EC:1.1.1.37]
117764310  malate dehydrogenase, cytoplasmic-like isoform X1 [KO:K00025] [EC:1.1.1.37]
117764363  LOW QUALITY PROTEIN: malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
117776389  mdh2; malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
117764822  cs; citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
117766231  aconitate hydratase, mitochondrial-like [KO:K01681] [EC:4.2.1.3]
117753205  aco2; aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
117779162  aco1; cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
117774364  acat1; acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
117758115  acat2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
117758752  mcee; methylmalonyl-CoA epimerase, mitochondrial [KO:K05606] [EC:5.1.99.1]
117775895  pcca; propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
117755614  pccb; propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
117758141  mut; methylmalonyl-CoA mutase, mitochondrial [KO:K01847] [EC:5.4.99.2]
117767015  hao1; hydroxyacid oxidase 1 isoform X1 [KO:K11517] [EC:1.1.3.15]
117755291  hao2; hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
117763812  cat; catalase [KO:K03781] [EC:1.11.1.6]
117769138  grhpra; glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
117770908  grhprb; glyoxylate reductase/hydroxypyruvate reductase b [KO:K00049] [EC:1.1.1.79 1.1.1.81]
117752884  pgp; glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
117778676  agxtb; alanine--glyoxylate and serine--pyruvate aminotransferase b [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
117760295  agxta; alanine--glyoxylate and serine--pyruvate aminotransferase a [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
117778195  glula; LOW QUALITY PROTEIN: glutamate-ammonia ligase (glutamine synthase) a [KO:K01915] [EC:6.3.1.2]
117760221  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
117760238  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
117760412  glulb; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
117771663  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
117766252  shmt1; serine hydroxymethyltransferase, cytosolic [KO:K00600] [EC:2.1.2.1]
117761482  shmt2; serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
117764066  serine hydroxymethyltransferase, mitochondrial-like isoform X1 [KO:K00600] [EC:2.1.2.1]
117767286  gldc; glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
117764191  amt; aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
117763089  dldh; dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
117759356  gcshb; glycine cleavage system protein H (aminomethyl carrier), b [KO:K02437]
117762690  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
117760774  hyi; putative hydroxypyruvate isomerase isoform X1 [KO:K01816] [EC:5.3.1.22]
117761392  glyctk; glycerate kinase [KO:K11529] [EC:2.7.1.165]
117760502  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
117777454  afmid; kynurenine formamidase [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hhip00010  Glycolysis / Gluconeogenesis
hhip00020  Citrate cycle (TCA cycle)
hhip00030  Pentose phosphate pathway
hhip00053  Ascorbate and aldarate metabolism
hhip00071  Fatty acid degradation
hhip00230  Purine metabolism
hhip00250  Alanine, aspartate and glutamate metabolism
hhip00260  Glycine, serine and threonine metabolism
hhip00620  Pyruvate metabolism
hhip00750  Vitamin B6 metabolism
hhip00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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