KEGG   PATHWAY: hsyr00480
Entry
hsyr00480                   Pathway                                
Name
Glutathione metabolism - Hibiscus syriacus (Rose-of-Sharon)
Class
Metabolism; Metabolism of other amino acids
Pathway map
hsyr00480  Glutathione metabolism
hsyr00480

Module
hsyr_M00118  Glutathione biosynthesis, glutamate => glutathione [PATH:hsyr00480]
Other DBs
GO: 0006749
Organism
Hibiscus syriacus (Rose-of-Sharon) [GN:hsyr]
Gene
120180101  glutathione hydrolase 3-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120181639  glutathione hydrolase 1-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120184608  glutathione hydrolase 1-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120136233  glutathione hydrolase 1-like isoform X1 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120124228  glutathione hydrolase 3-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120192341  glutathione hydrolase 3-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120150067  gamma-glutamylcyclotransferase 2-1-like [KO:K22596] [EC:4.3.2.9]
120173541  gamma-glutamylcyclotransferase 2-1-like [KO:K22596] [EC:4.3.2.9]
120212226  LOW QUALITY PROTEIN: gamma-glutamylcyclotransferase 2-3 [KO:K22596] [EC:4.3.2.9]
120214995  5-oxoprolinase-like [KO:K01469] [EC:3.5.2.9]
120213730  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
120202610  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
120206702  glutamate--cysteine ligase, chloroplastic-like isoform X1 [KO:K01919] [EC:6.3.2.2]
120191748  glutamate--cysteine ligase, chloroplastic-like isoform X1 [KO:K01919] [EC:6.3.2.2]
120207450  glutathione synthetase, chloroplastic isoform X1 [KO:K21456] [EC:6.3.2.3]
120132224  LOW QUALITY PROTEIN: leucine aminopeptidase 2, chloroplastic-like [KO:K01255] [EC:3.4.11.1]
120163577  LOW QUALITY PROTEIN: puromycin-sensitive aminopeptidase-like [KO:K01256] [EC:3.4.11.2]
120113440  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120146091  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120146725  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120146900  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
120146901  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
120162465  glutathione S-transferase U25-like [KO:K00799] [EC:2.5.1.18]
120162466  probable glutathione S-transferase parC [KO:K00799] [EC:2.5.1.18]
120162467  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120162468  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120162917  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120179811  glutathione S-transferase U16-like [KO:K00799] [EC:2.5.1.18]
120113929  glutathione S-transferase F12-like [KO:K00799] [EC:2.5.1.18]
120114394  glutathione S-transferase T1-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120130654  glutathione S-transferase U28-like [KO:K00799] [EC:2.5.1.18]
120196802  glutathione S-transferase F9-like [KO:K00799] [EC:2.5.1.18]
120214138  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
120164477  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120164561  probable glutathione S-transferase parC [KO:K00799] [EC:2.5.1.18]
120164637  probable glutathione S-transferase parA [KO:K00799] [EC:2.5.1.18]
120197944  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
120198568  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
120198569  glutathione S-transferase L1-like [KO:K00799] [EC:2.5.1.18]
120115937  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120115997  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120132506  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
120133066  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
120133437  glutathione S-transferase F9-like [KO:K00799] [EC:2.5.1.18]
120165737  glutathione S-transferase F6-like [KO:K00799] [EC:2.5.1.18]
120182047  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120182818  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120199638  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120199639  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120199717  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
120116967  glutathione S-transferase U9-like [KO:K00799] [EC:2.5.1.18]
120150197  probable glutathione S-transferase parA [KO:K00799] [EC:2.5.1.18]
120150795  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120166210  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120184018  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120200047  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
120151116  glutathione S-transferase U18-like [KO:K00799] [EC:2.5.1.18]
120218236  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120218237  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120152355  LOW QUALITY PROTEIN: microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120153046  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
120153113  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120202715  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120218642  glutathione S-transferase F8, chloroplastic-like [KO:K00799] [EC:2.5.1.18]
120219424  probable glutathione S-transferase parA [KO:K00799] [EC:2.5.1.18]
120136756  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120137306  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
120153391  glutathione S-transferase F6-like [KO:K00799] [EC:2.5.1.18]
120153798  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120169236  glutathione S-transferase U7-like [KO:K00799] [EC:2.5.1.18]
120170114  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120186860  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
120120918  glutathione S-transferase U25-like [KO:K00799] [EC:2.5.1.18]
120137999  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120138018  glutathione S-transferase U19-like [KO:K00799] [EC:2.5.1.18]
120138122  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
120155324  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
120188282  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120188283  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120205220  probable glutathione S-transferase parA [KO:K00799] [EC:2.5.1.18]
120123327  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120124001  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120124002  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
120124003  glutathione S-transferase L1-like [KO:K00799] [EC:2.5.1.18]
120206185  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
120124527  glutathione S-transferase U7-like [KO:K00799] [EC:2.5.1.18]
120141147  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
120158208  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120173712  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120190712  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120207476  LOW QUALITY PROTEIN: glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
120126056  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120159250  glutathione S-transferase U7-like [KO:K00799] [EC:2.5.1.18]
120159256  glutathione S-transferase U7-like [KO:K00799] [EC:2.5.1.18]
120208244  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120127041  probable glutathione S-transferase parC [KO:K00799] [EC:2.5.1.18]
120127044  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120143346  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120143726  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
120193043  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120127294  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
120127359  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120128237  LOW QUALITY PROTEIN: glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120161046  glutathione S-transferase F6-like [KO:K00799] [EC:2.5.1.18]
120161090  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
120176932  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120176944  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120176955  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120176956  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120193624  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
120128414  glutathione transferase GST 23-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120129138  glutathione S-transferase U16-like [KO:K00799] [EC:2.5.1.18]
120129183  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120161842  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120161854  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120212105  glutathione S-transferase F9-like [KO:K00799] [EC:2.5.1.18]
120213283  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120115371  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120182767  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120205539  glutathione S-transferase DHAR1, mitochondrial-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120140101  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120161231  glutathione S-transferase DHAR3, chloroplastic-like isoform X1 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120179988  LOW QUALITY PROTEIN: glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
120119344  glutathione reductase, chloroplastic [KO:K00383] [EC:1.8.1.7]
120152638  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
120138814  glutathione reductase, cytosolic-like [KO:K00383] [EC:1.8.1.7]
120143563  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
120178334  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
120197124  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120169981  LOW QUALITY PROTEIN: isocitrate dehydrogenase [NADP], chloroplastic/mitochondrial-like [KO:K00031] [EC:1.1.1.42]
120123306  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120141442  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120125206  isocitrate dehydrogenase [NADP], chloroplastic/mitochondrial-like [KO:K00031] [EC:1.1.1.42]
120177121  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
120161818  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120113947  6-phosphogluconate dehydrogenase, decarboxylating 1 [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120114471  6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120136883  6-phosphogluconate dehydrogenase, decarboxylating 1-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120120824  6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120120955  LOW QUALITY PROTEIN: 6-phosphogluconate dehydrogenase, decarboxylating 2-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120155356  6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120166148  LOW QUALITY PROTEIN: glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120167157  inactive glucose-6-phosphate 1-dehydrogenase 4, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120136513  glucose-6-phosphate 1-dehydrogenase 6, cytoplasmic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120187339  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120203153  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like isoform X1 [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120144343  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120114396  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120197489  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120214312  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120165157  probable glutathione peroxidase 5 [KO:K00432] [EC:1.11.1.9]
120199713  probable glutathione peroxidase 8 [KO:K00432] [EC:1.11.1.9]
120117401  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120150950  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120155239  probable glutathione peroxidase 8 [KO:K00432] [EC:1.11.1.9]
120122298  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120172086  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120188932  probable glutathione peroxidase 2 [KO:K00432] [EC:1.11.1.9]
120140063  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120207774  phospholipid hydroperoxide glutathione peroxidase, chloroplastic-like [KO:K00432] [EC:1.11.1.9]
120209565  LOW QUALITY PROTEIN: 1-Cys peroxiredoxin-like [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
120127286  LOW QUALITY PROTEIN: 1-Cys peroxiredoxin-like [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
120213305  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
120211026  uncharacterized protein LOC120211026 [KO:K01581] [EC:4.1.1.17]
120148962  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
120215255  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
120216126  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120116883  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120117166  spermidine synthase-like [KO:K00797] [EC:2.5.1.16]
120184207  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120171705  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
120140014  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120206493  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
120178123  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
120196143  L-ascorbate peroxidase 1, cytosolic-like [KO:K00434] [EC:1.11.1.11]
120131431  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
120180125  L-ascorbate peroxidase 1, cytosolic-like [KO:K00434] [EC:1.11.1.11]
120148287  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
120215348  L-ascorbate peroxidase, cytosolic-like isoform X1 [KO:K00434] [EC:1.11.1.11]
120216192  probable L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
120184814  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
120154056  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
120139822  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
120141606  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
120192198  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
120193889  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
120145805  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
120177897  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
120163530  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
120184586  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
120174400  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
120212511  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120114370  ribonucleoside-diphosphate reductase small chain A-like [KO:K10808] [EC:1.17.4.1]
120185610  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120169996  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
120159456  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120128440  ribonucleoside-diphosphate reductase small chain A-like isoform X1 [KO:K10808] [EC:1.17.4.1]
Compound
C00005  NADPH
C00006  NADP+
C00024  Acetyl-CoA
C00025  L-Glutamate
C00037  Glycine
C00051  Glutathione
C00072  Ascorbate
C00077  L-Ornithine
C00097  L-Cysteine
C00127  Glutathione disulfide
C00134  Putrescine
C00151  L-Amino acid
C00315  Spermidine
C00669  gamma-L-Glutamyl-L-cysteine
C00750  Spermine
C01322  RX
C01419  Cys-Gly
C01672  Cadaverine
C01879  5-Oxoproline
C02090  Trypanothione
C02320  R-S-Glutathione
C03170  Trypanothione disulfide
C03646  Bis-gamma-glutamylcystine
C03740  (5-L-Glutamyl)-L-amino acid
C05422  Dehydroascorbate
C05726  S-Substituted L-cysteine
C05727  S-Substituted N-acetyl-L-cysteine
C05729  R-S-Cysteinylglycine
C05730  Glutathionylspermidine
C16562  Glutathionylspermine
C16563  Bis(glutathionyl)spermine
C16564  Bis(glutathionyl)spermine disulfide
C16565  Aminopropylcadaverine
C16566  Glutathionylaminopropylcadaverine
C16567  Homotrypanothione
C16568  Homotrypanothione disulfide
C16663  Tryparedoxin
C16664  Tryparedoxin disulfide
Reference
PMID:12675513
  Authors
Josch C, Klotz LO, Sies H.
  Title
Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver.
  Journal
Biol Chem 384:213-8 (2003)
DOI:10.1515/BC.2003.023
Reference
PMID:18482986
  Authors
Chu L, Lai Y, Xu X, Eddy S, Yang S, Song L, Kolodrubetz D.
  Title
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Related
pathway
hsyr00220  Arginine biosynthesis
hsyr00250  Alanine, aspartate and glutamate metabolism
hsyr00270  Cysteine and methionine metabolism
hsyr00430  Taurine and hypotaurine metabolism
hsyr00460  Cyanoamino acid metabolism
KO pathway
ko00480   
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