KEGG   PATHWAY: kar00630
Entry
kar00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Klebsiella africana
Class
Metabolism; Carbohydrate metabolism
Pathway map
kar00630  Glyoxylate and dicarboxylate metabolism
kar00630

Module
kar_M00012  Glyoxylate cycle [PATH:kar00630]
kar_M00621  Glycine cleavage system [PATH:kar00630]
Other DBs
GO: 0046487 0043648
Organism
Klebsiella africana [GN:kar]
Gene
LGL98_23690  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
LGL98_23290  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
LGL98_23695  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
LGL98_02415  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
LGL98_17640  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
LGL98_18870  citrate synthase [KO:K01647] [EC:2.3.3.1]
LGL98_14620  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
LGL98_20815  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
LGL98_12570  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LGL98_12710  thiolase family protein [KO:K00626] [EC:2.3.1.9]
LGL98_04275  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LGL98_10625  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LGL98_14810  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
LGL98_15955  ghrA; glyoxylate/hydroxypyruvate reductase GhrA [KO:K12972] [EC:1.1.1.79 1.1.1.81]
LGL98_05850  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
LGL98_01015  ghrB; glyoxylate/hydroxypyruvate reductase GhrB [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
LGL98_01835  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
LGL98_24830  glnA; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LGL98_06275  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LGL98_03925  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
LGL98_03915  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
LGL98_20835  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LGL98_03920  gcvH; glycine cleavage system protein GcvH [KO:K02437]
LGL98_02955  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
LGL98_12730  glycerate kinase [KO:K00865] [EC:2.7.1.165]
LGL98_02960  garK; glycerate 2-kinase [KO:K00865] [EC:2.7.1.165]
LGL98_04930  glycerate kinase [KO:K00865] [EC:2.7.1.165]
LGL98_14710  glycerate kinase [KO:K11529] [EC:2.7.1.165]
LGL98_13785  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
LGL98_04815  fucO; lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
LGL98_02435  ttdA; L(+)-tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
LGL98_02440  ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
LGL98_14715  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
LGL98_16150  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
LGL98_09075  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LGL98_24720  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
LGL98_24725  fdxH; formate dehydrogenase subunit beta [KO:K00124]
LGL98_24730  fdoI; formate dehydrogenase cytochrome b556 subunit [KO:K00127]
LGL98_09905  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
kar00010  Glycolysis / Gluconeogenesis
kar00020  Citrate cycle (TCA cycle)
kar00030  Pentose phosphate pathway
kar00053  Ascorbate and aldarate metabolism
kar00071  Fatty acid degradation
kar00230  Purine metabolism
kar00250  Alanine, aspartate and glutamate metabolism
kar00260  Glycine, serine and threonine metabolism
kar00620  Pyruvate metabolism
kar00710  Carbon fixation by Calvin cycle
kar00750  Vitamin B6 metabolism
kar00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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