KEGG   PATHWAY: kpe00630
Entry
kpe00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Klebsiella variicola 342
Class
Metabolism; Carbohydrate metabolism
Pathway map
kpe00630  Glyoxylate and dicarboxylate metabolism
kpe00630

Module
kpe_M00012  Glyoxylate cycle [PATH:kpe00630]
kpe_M00621  Glycine cleavage system [PATH:kpe00630]
Other DBs
GO: 0046487 0043648
Organism
Klebsiella variicola 342 [GN:kpe]
Gene
KPK_5278  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
KPK_5191  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
KPK_5279  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
KPK_0477  mdh; malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
KPK_4104  putative citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
KPK_3843  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
KPK_3162  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
KPK_4725  aconitase family protein [KO:K01681] [EC:4.2.1.3]
KPK_4614  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
KPK_2276  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPK_2972  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPK_0844  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPK_3205  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
KPK_2233  catalase [KO:K03781] [EC:1.11.1.6]
KPK_1152  D-isomer specific 2-hydroxyacid dehydrogenase family protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPK_3501  putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPK_0190  tkrA; 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
KPK_0360  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
KPK_5504  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
KPK_1246  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KPK_0761  gcvP; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
KPK_0759  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
KPK_4619  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
KPK_4463  acoD; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
KPK_0760  gcvH; glycine cleavage system H protein [KO:K02437]
KPK_0573  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
KPK_0993  putative glycerate kinase [KO:K00865] [EC:2.7.1.165]
KPK_0574  garK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
KPK_3184  ttuD; hydroxypyruvate reductase TtuD [KO:K11529] [EC:2.7.1.165]
KPK_2959  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
KPK_0969  fucO; lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
KPK_0481  ddtA; L(+)-tartrate dehydratase, alpha subunit [KO:K03779] [EC:4.2.1.32]
KPK_0482  ttdB; L(+)-tartrate dehydratase, beta subunit [KO:K03780] [EC:4.2.1.32]
KPK_3185  ttuC; tartrate dehydrogenase TtuC [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KPK_3545  tartrate dehydrogenase/decarboxylase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KPK_1924  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
KPK_5492  fdoG; formate dehydrogenase-O, major subunit, selenocysteine-containing [KO:K00123] [EC:1.17.1.9]
KPK_5493  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
KPK_5494  fdoI; formate dehydrogenase-O, gamma subunit [KO:K00127]
KPK_2102  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
kpe00010  Glycolysis / Gluconeogenesis
kpe00020  Citrate cycle (TCA cycle)
kpe00030  Pentose phosphate pathway
kpe00053  Ascorbate and aldarate metabolism
kpe00071  Fatty acid degradation
kpe00230  Purine metabolism
kpe00250  Alanine, aspartate and glutamate metabolism
kpe00260  Glycine, serine and threonine metabolism
kpe00620  Pyruvate metabolism
kpe00710  Carbon fixation by Calvin cycle
kpe00750  Vitamin B6 metabolism
kpe00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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