KEGG   PATHWAY: lav00190
Entry
lav00190                    Pathway                                
Name
Oxidative phosphorylation - Loxodonta africana (African savanna elephant)
Class
Metabolism; Energy metabolism
Pathway map
lav00190  Oxidative phosphorylation
lav00190

Module
lav_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:lav00190]
lav_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:lav00190]
lav_M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:lav00190]
lav_M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:lav00190]
lav_M00148  Succinate dehydrogenase (ubiquinone) [PATH:lav00190]
lav_M00151  Cytochrome bc1 complex respiratory unit [PATH:lav00190]
lav_M00152  Cytochrome bc1 complex [PATH:lav00190]
lav_M00160  V-type ATPase, eukaryotes [PATH:lav00190]
Organism
Loxodonta africana (African savanna elephant) [GN:lav]
Gene
808794  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
808792  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
808786  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
808784  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
808785  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
808793  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
808795  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
100677530  NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1 [KO:K03934] [EC:7.1.1.2]
100654713  NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1 [KO:K03935] [EC:7.1.1.2]
100671569  NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1 [KO:K03936] [EC:7.1.1.2]
100665872  NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937]
100669401  NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
100658561  NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
100677129  NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial [KO:K03940] [EC:7.1.1.2]
100671885  NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941] [EC:7.1.1.2]
100669323  NDUFV1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial isoform X1 [KO:K03942] [EC:7.1.1.2]
100673749  NDUFV2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
100670560  NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944]
111751867  NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
100654461  NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
100661324  NDUFA3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
100676572  NDUFA4L2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
100669927  NDUFA4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
100668904  cytochrome c oxidase subunit NDUFA4 [KO:K03948]
100661044  NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
100654354  NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
100663654  NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
100675084  NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
100669755  NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
111752617  NDUFA10; LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
100671498  NDUFAB1; acyl carrier protein, mitochondrial [KO:K03955]
100675610  NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
100661505  NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
100674818  NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 isoform X1 [KO:K11353]
100660762  NDUFB1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
100664407  NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958]
100661123  NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 isoform X3 [KO:K03959]
100674815  NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
100669954  NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
100661329  NDUFB6; LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
100675297  NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
100663225  NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
100659326  NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
100664859  NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
100659182  NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
100676791  NDUFC1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
104846185  NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial-like [KO:K03967]
100664015  NDUFC2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
100141371  SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [KO:K00234] [EC:1.3.5.1]
100141376  SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
100672637  SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial [KO:K00236]
100668090  SDHD; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial [KO:K00237]
100655924  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial-like [KO:K00237]
100667241  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
808783  CYTB; cytochrome b [KO:K00412]
100666414  LOW QUALITY PROTEIN: cytochrome c1, heme protein, mitochondrial [KO:K00413]
100674803  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
100668947  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
100676911  cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416]
100669937  cytochrome b-c1 complex subunit 7 [KO:K00417]
100662438  cytochrome b-c1 complex subunit 8 [KO:K00418]
100659857  cytochrome b-c1 complex subunit 9 isoform X2 [KO:K00419]
100666038  cytochrome b-c1 complex subunit 10 [KO:K00420]
100671416  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
808787  COX3; cytochrome c oxidase subunit III [KO:K02262]
808791  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
808790  COX2; cytochrome c oxidase subunit II [KO:K02261]
100655578  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
100659426  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
100659010  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
100663363  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
100674944  cytochrome c oxidase subunit 6A1, mitochondrial isoform X1 [KO:K02266]
100676021  cytochrome c oxidase subunit 6B2 [KO:K02267]
100656914  cytochrome c oxidase subunit 6B1 isoform X2 [KO:K02267]
100673278  cytochrome c oxidase subunit 6C [KO:K02268]
100659078  cytochrome c oxidase subunit 7A-related protein, mitochondrial isoform X2 [KO:K02270]
100663191  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
100657307  cytochrome c oxidase subunit 7A1, mitochondrial isoform X1 [KO:K02270]
100658215  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
100666763  cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
111749980  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
100665257  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
100666553  cytochrome c oxidase assembly protein COX11, mitochondrial isoform X1 [KO:K02258]
100665789  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
100675578  cytochrome c oxidase copper chaperone [KO:K02260]
100654286  cytochrome c, testis-specific [KO:K08738]
100657132  cytochrome c [KO:K08738]
100666715  ATP5F1A; ATP synthase subunit alpha, mitochondrial [KO:K02132]
100673733  ATP5F1B; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
100655730  ATP5F1C; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
100676000  ATP5F1D; ATP synthase subunit delta, mitochondrial [KO:K02134]
100669509  ATP5F1E; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
111748544  LOW QUALITY PROTEIN: ATP synthase subunit epsilon, mitochondrial-like [KO:K02135]
111749757  LOW QUALITY PROTEIN: ATP synthase subunit epsilon-like protein, mitochondrial [KO:K02135]
100670894  ATP5PO; ATP synthase subunit O, mitochondrial isoform X1 [KO:K02137]
808788  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
100675936  ATP5PB; ATP synthase F(0) complex subunit B1, mitochondrial isoform X1 [KO:K02127]
100657700  ATP5MC3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
100675957  ATP5MC1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
100663668  ATP5MC2; ATP synthase F(0) complex subunit C2, mitochondrial isoform X2 [KO:K02128]
100658039  ATP5PD; ATP synthase subunit d, mitochondrial [KO:K02138]
100654312  ATP5ME; ATP synthase subunit e, mitochondrial [KO:K02129]
100662026  ATP5MF; ATP synthase subunit f, mitochondrial [KO:K02130]
100677671  ATP5MG; ATP synthase subunit g, mitochondrial [KO:K02140]
100657531  ATP5PF; ATP synthase-coupling factor 6, mitochondrial [KO:K02131]
100653567  ATP6V1A; V-type proton ATPase catalytic subunit A isoform X1 [KO:K02145] [EC:7.1.2.2]
100666832  ATP6V1B2; LOW QUALITY PROTEIN: V-type proton ATPase subunit B, brain isoform [KO:K02147]
100666469  ATP6V1B1; V-type proton ATPase subunit B, kidney isoform [KO:K02147]
100676877  ATP6V1C1; V-type proton ATPase subunit C 1 [KO:K02148]
100665801  ATP6V1C2; LOW QUALITY PROTEIN: V-type proton ATPase subunit C 2 [KO:K02148]
100658198  ATP6V1D; V-type proton ATPase subunit D [KO:K02149]
100662195  ATP6V1E1; V-type proton ATPase subunit E 1 [KO:K02150]
100654530  ATP6V1E2; V-type proton ATPase subunit E 2 isoform X1 [KO:K02150]
100667006  ATP6V1F; V-type proton ATPase subunit F [KO:K02151]
100668535  ATP6V1G3; V-type proton ATPase subunit G 3 [KO:K02152]
100656481  ATP6V1G1; V-type proton ATPase subunit G 1 [KO:K02152]
100653889  ATP6V1G2; V-type proton ATPase subunit G 2 [KO:K02152]
100668341  ATP6V1H; V-type proton ATPase subunit H isoform X1 [KO:K02144]
100670350  ATP6V0A1; V-type proton ATPase 116 kDa subunit a isoform X4 [KO:K02154]
100661949  ATP6V0A2; V-type proton ATPase 116 kDa subunit a [KO:K02154]
100664975  ATP6V0A4; V-type proton ATPase 116 kDa subunit a [KO:K02154]
100667060  TCIRG1; V-type proton ATPase 116 kDa subunit a [KO:K02154]
100668758  ATP6V0C; V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
100669026  ATP6V0B; V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
100662095  ATP6V0D2; V-type proton ATPase subunit d 2 [KO:K02146]
100677484  ATP6V0D1; V-type proton ATPase subunit d 1 isoform X2 [KO:K02146]
100666036  ATP6V0E1; V-type proton ATPase subunit e 1 [KO:K02153]
111747829  ATP6V0E2; V-type proton ATPase subunit e 2 isoform X1 [KO:K02153]
100667446  ATP6AP1; V-type proton ATPase subunit S1 [KO:K03662]
100670470  ATP4A; potassium-transporting ATPase alpha chain 1 [KO:K01542] [EC:7.2.2.19]
100663989  ATP4B; potassium-transporting ATPase subunit beta [KO:K01543] [EC:7.2.2.19]
100657835  potassium-transporting ATPase alpha chain 2-like isoform X1 [KO:K01544] [EC:7.2.2.19]
100657258  potassium-transporting ATPase alpha chain 2 [KO:K01544] [EC:7.2.2.19]
100665602  PPA2; inorganic pyrophosphatase 2, mitochondrial isoform X1 [KO:K01507] [EC:3.6.1.1]
100654586  PPA1; inorganic pyrophosphatase [KO:K01507] [EC:3.6.1.1]
100660716  LHPP; LOW QUALITY PROTEIN: phospholysine phosphohistidine inorganic pyrophosphate phosphatase [KO:K11725] [EC:3.6.1.1 3.1.3.-]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00080  H+
C00122  Fumarate
C00536  Triphosphate
Reference
PMID:16469879
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
PMID:16584177
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   
LinkDB

DBGET integrated database retrieval system