KEGG   PATHWAY: lne00630
Entry
lne00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Labrys sp. KNU-23
Class
Metabolism; Carbohydrate metabolism
Pathway map
lne00630  Glyoxylate and dicarboxylate metabolism
lne00630

Module
lne_M00012  Glyoxylate cycle [PATH:lne00630]
lne_M00621  Glycine cleavage system [PATH:lne00630]
lne_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:lne00630]
Other DBs
GO: 0046487 0043648
Organism
Labrys sp. KNU-23 [GN:lne]
Gene
FZC33_32620  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
FZC33_19525  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
FZC33_22915  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
FZC33_29625  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
FZC33_27275  malate synthase G [KO:K01638] [EC:2.3.3.9]
FZC33_25570  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
FZC33_11050  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
FZC33_21855  citrate synthase [KO:K01647] [EC:2.3.3.1]
FZC33_21860  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
FZC33_18260  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
FZC33_08685  sucD; succinate--CoA ligase subunit alpha [KO:K08692] [EC:6.2.1.9]
FZC33_08690  malate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
FZC33_28625  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
FZC33_21040  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
FZC33_25935  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
FZC33_29630  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
FZC33_21035  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
FZC33_31810  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
FZC33_08695  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
FZC33_21920  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
FZC33_31580  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
FZC33_21925  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
FZC33_31565  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
FZC33_27605  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
FZC33_21915  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
FZC33_29240  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
FZC33_29245  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
FZC33_27305  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
FZC33_27300  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
FZC33_27295  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
FZC33_00705  catalase [KO:K03781] [EC:1.11.1.6]
FZC33_24330  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
FZC33_24975  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
FZC33_14120  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
FZC33_06940  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
FZC33_30120  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
FZC33_31530  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
FZC33_10380  form I ribulose bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
FZC33_10375  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
FZC33_08700  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
FZC33_09850  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_10675  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
FZC33_31095  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_26750  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_27390  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_15520  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_16730  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_17815  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_24560  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_24890  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FZC33_12585  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
FZC33_03930  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
FZC33_04590  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
FZC33_27820  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
FZC33_27815  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
FZC33_27830  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
FZC33_04580  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
FZC33_26175  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
FZC33_26180  DUF1989 domain-containing protein [KO:K00605] [EC:2.1.2.10]
FZC33_33195  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
FZC33_25595  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
FZC33_27825  gcvH; glycine cleavage system protein GcvH [KO:K02437]
FZC33_04585  gcvH; glycine cleavage system protein GcvH [KO:K02437]
FZC33_15720  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
FZC33_22170  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
FZC33_34210  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
FZC33_06580  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
FZC33_15725  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
FZC33_22175  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
FZC33_15730  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
FZC33_22180  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
FZC33_22185  glycerate kinase [KO:K11529] [EC:2.7.1.165]
FZC33_30095  glycerate kinase [KO:K11529] [EC:2.7.1.165]
FZC33_04835  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
FZC33_08500  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
FZC33_18310  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
FZC33_24045  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
FZC33_24055  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
FZC33_24060  NADH-quinone oxidoreductase subunit NuoF [KO:K00124]
FZC33_24065  formate dehydrogenase subunit gamma [KO:K00127]
FZC33_02595  alpha/beta fold hydrolase [KO:K01432] [EC:3.5.1.9]
FZC33_20390  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
FZC33_28960  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
lne00010  Glycolysis / Gluconeogenesis
lne00020  Citrate cycle (TCA cycle)
lne00030  Pentose phosphate pathway
lne00053  Ascorbate and aldarate metabolism
lne00071  Fatty acid degradation
lne00230  Purine metabolism
lne00250  Alanine, aspartate and glutamate metabolism
lne00260  Glycine, serine and threonine metabolism
lne00620  Pyruvate metabolism
lne00710  Carbon fixation by Calvin cycle
lne00750  Vitamin B6 metabolism
lne00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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