KEGG   PATHWAY: mbrd00630
Entry
mbrd00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium branderi
Class
Metabolism; Carbohydrate metabolism
Pathway map
mbrd00630  Glyoxylate and dicarboxylate metabolism
mbrd00630

Module
mbrd_M00012  Glyoxylate cycle [PATH:mbrd00630]
mbrd_M00621  Glycine cleavage system [PATH:mbrd00630]
mbrd_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mbrd00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium branderi [GN:mbrd]
Gene
MBRA_38210  aceA; isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1]
MBRA_09370  icl; isocitrate lyase 1 [KO:K01637] [EC:4.1.3.1]
MBRA_18770  hypothetical protein [KO:K01895] [EC:6.2.1.1]
MBRA_29290  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MBRA_39470  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MBRA_30250  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MBRA_24580  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MBRA_24600  gltA2; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MBRA_27790  gltA1; citrate synthase [KO:K01647] [EC:2.3.3.1]
MBRA_42380  acn; aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
MBRA_43060  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MBRA_31070  fadA4; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_31440  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_39200  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_51020  atoB_2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_56700  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_57600  atoB_3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_57730  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_57960  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_12290  fadA2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_20130  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_20270  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_20500  ltp3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_21740  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_24200  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_24940  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_24950  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_25530  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_27020  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_31730  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MBRA_51140  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
MBRA_31060  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MBRA_03960  accA3; acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MBRA_03900  propionyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MBRA_03910  hypothetical protein [KO:K27095]
MBRA_35600  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MBRA_42120  mutB; putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MBRA_42130  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MBRA_22800  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MBRA_22790  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MBRA_30410  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MBRA_04110  catalase [KO:K03781] [EC:1.11.1.6]
MBRA_12370  katA_1; catalase [KO:K03781] [EC:1.11.1.6]
MBRA_12380  katA_2; catalase [KO:K03781] [EC:1.11.1.6]
MBRA_35880  glnA2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MBRA_36000  glnA1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MBRA_38960  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MBRA_27220  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MBRA_39490  gcvP; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MBRA_36100  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MBRA_09420  lpdC; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MBRA_39540  gcvH; glycine cleavage system H protein [KO:K02437]
MBRA_36160  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MBRA_30290  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MBRA_44850  hypothetical oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mbrd00010  Glycolysis / Gluconeogenesis
mbrd00020  Citrate cycle (TCA cycle)
mbrd00030  Pentose phosphate pathway
mbrd00053  Ascorbate and aldarate metabolism
mbrd00071  Fatty acid degradation
mbrd00230  Purine metabolism
mbrd00250  Alanine, aspartate and glutamate metabolism
mbrd00260  Glycine, serine and threonine metabolism
mbrd00620  Pyruvate metabolism
mbrd00710  Carbon fixation by Calvin cycle
mbrd00750  Vitamin B6 metabolism
mbrd00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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