KEGG   PATHWAY: mcoo00630
Entry
mcoo00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium cookii
Class
Metabolism; Carbohydrate metabolism
Pathway map
mcoo00630  Glyoxylate and dicarboxylate metabolism
mcoo00630

Module
mcoo_M00012  Glyoxylate cycle [PATH:mcoo00630]
mcoo_M00621  Glycine cleavage system [PATH:mcoo00630]
mcoo_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mcoo00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium cookii [GN:mcoo]
Gene
MCOO_39060  aceA_1; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MCOO_46070  aceA_2; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MCOO_28210  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MCOO_08990  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MCOO_18420  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MCOO_19950  citrate synthase [KO:K01647] [EC:2.3.3.1]
MCOO_23300  gltA2; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MCOO_23330  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MCOO_05250  acn; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MCOO_09220  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_09850  transporter [KO:K00626] [EC:2.3.1.9]
MCOO_16830  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_17160  fadA4; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_20700  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_22540  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_23110  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_23670  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_26680  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_26970  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_27150  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_36050  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MCOO_17170  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MCOO_44310  putative bifunctional protein acetyl-/propionyl-CoA carboxylase (alpha chain) AccA3 [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MCOO_44360  propionyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MCOO_44350  accE5; bifunctional protein acetyl-/propionyl-CoAcarboxylase subunit epsilon AccE [KO:K27095]
MCOO_12840  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MCOO_05460  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MCOO_05470  mutB; putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MCOO_13330  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MCOO_13340  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MCOO_17880  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MCOO_13020  catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MCOO_13210  katA; catalase [KO:K03781] [EC:1.11.1.6]
MCOO_46460  hypothetical protein [KO:K03781] [EC:1.11.1.6]
MCOO_12610  hypothetical protein [KO:K01091] [EC:3.1.3.18]
MCOO_00770  glnA4; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MCOO_09500  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MCOO_12360  glnA_1; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MCOO_12480  glnA2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MCOO_13170  glnN; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MCOO_45860  glnA_2; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MCOO_20500  glyA1; serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
MCOO_08960  gcvP; putative glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MCOO_12250  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MCOO_39000  lpdC; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MCOO_08910  gcvH; glycine cleavage system H protein [KO:K02437]
MCOO_24160  6-phosphogluconate dehydrogenase [KO:K00042] [EC:1.1.1.60]
MCOO_12120  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MCOO_18050  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MCOO_17570  hypothetical oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
MCOO_17580  hypothetical oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
MCOO_05890  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MCOO_03310  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mcoo00010  Glycolysis / Gluconeogenesis
mcoo00020  Citrate cycle (TCA cycle)
mcoo00030  Pentose phosphate pathway
mcoo00053  Ascorbate and aldarate metabolism
mcoo00071  Fatty acid degradation
mcoo00230  Purine metabolism
mcoo00250  Alanine, aspartate and glutamate metabolism
mcoo00260  Glycine, serine and threonine metabolism
mcoo00620  Pyruvate metabolism
mcoo00710  Carbon fixation by Calvin cycle
mcoo00750  Vitamin B6 metabolism
mcoo00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system