KEGG   PATHWAY: mfj00630
Entry
mfj00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium florentinum
Class
Metabolism; Carbohydrate metabolism
Pathway map
mfj00630  Glyoxylate and dicarboxylate metabolism
mfj00630

Module
mfj_M00012  Glyoxylate cycle [PATH:mfj00630]
mfj_M00621  Glycine cleavage system [PATH:mfj00630]
mfj_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mfj00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium florentinum [GN:mfj]
Gene
MFLOJ_27860  aceA_2; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MFLOJ_05100  aceA_1; isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1]
MFLOJ_39650  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MFLOJ_06280  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MFLOJ_49040  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MFLOJ_44610  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MFLOJ_44630  gltA2; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MFLOJ_47770  prpC; 2-methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
MFLOJ_11140  acn; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MFLOJ_18480  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_30610  fadA2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_05940  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_07740  transporter [KO:K00626] [EC:2.3.1.9]
MFLOJ_44170  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_44830  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_45350  atoB_1; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_45700  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_47160  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_50210  fadA4; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_50550  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_50840  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_55140  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_55160  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_40820  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_40910  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_41140  ltp3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_57820  atoB_2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MFLOJ_50200  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MFLOJ_22360  accA3; acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MFLOJ_22310  accD5; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MFLOJ_22320  hypothetical protein [KO:K27095]
MFLOJ_00440  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MFLOJ_10950  mutB; putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MFLOJ_10960  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MFLOJ_42810  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MFLOJ_42800  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MFLOJ_49190  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MFLOJ_58730  dehydrogenase [KO:K00104] [EC:1.1.99.14]
MFLOJ_33870  catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MFLOJ_13440  catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MFLOJ_39030  katA; catalase [KO:K03781] [EC:1.11.1.6]
MFLOJ_00680  hypothetical protein [KO:K01091] [EC:3.1.3.18]
MFLOJ_19010  glnA1_2; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MFLOJ_00860  glnA2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MFLOJ_00950  glnA1_1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MFLOJ_05700  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MFLOJ_08220  glnN; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MFLOJ_47340  glyA1; serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
MFLOJ_06400  gcvP; putative glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MFLOJ_01070  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MFLOJ_27910  lpd; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MFLOJ_06450  gcvH; glycine cleavage system H protein [KO:K02437]
MFLOJ_15360  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
MFLOJ_15340  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
MFLOJ_15350  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
MFLOJ_43460  6-phosphogluconate dehydrogenase [KO:K00042] [EC:1.1.1.60]
MFLOJ_15330  glxK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
MFLOJ_01130  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MFLOJ_49090  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MFLOJ_58290  cupin [KO:K01569] [EC:4.1.1.2]
MFLOJ_30760  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MFLOJ_15440  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MFLOJ_34020  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MFLOJ_34030  dehydrogenase [KO:K00123] [EC:1.17.1.9]
MFLOJ_34010  4Fe-4S ferredoxin [KO:K00124]
MFLOJ_32610  oxcA; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
MFLOJ_15500  oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mfj00010  Glycolysis / Gluconeogenesis
mfj00020  Citrate cycle (TCA cycle)
mfj00030  Pentose phosphate pathway
mfj00053  Ascorbate and aldarate metabolism
mfj00071  Fatty acid degradation
mfj00230  Purine metabolism
mfj00250  Alanine, aspartate and glutamate metabolism
mfj00260  Glycine, serine and threonine metabolism
mfj00620  Pyruvate metabolism
mfj00710  Carbon fixation by Calvin cycle
mfj00750  Vitamin B6 metabolism
mfj00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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