KEGG   PATHWAY: mflv00630
Entry
mflv00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium flavescens
Class
Metabolism; Carbohydrate metabolism
Pathway map
mflv00630  Glyoxylate and dicarboxylate metabolism
mflv00630

Module
mflv_M00012  Glyoxylate cycle [PATH:mflv00630]
mflv_M00621  Glycine cleavage system [PATH:mflv00630]
mflv_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mflv00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium flavescens [GN:mflv]
Gene
NCTC10271_04509  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
NCTC10271_02424  icl; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
NCTC10271_00372  acs; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
NCTC10271_02551  glcB; malate synthase [KO:K01638] [EC:2.3.3.9]
NCTC10271_01256  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NCTC10271_00738  citA; citrate synthase [KO:K01647] [EC:2.3.3.1]
NCTC10271_00741  gltA2; citrate synthase I, hexameric type [KO:K01647] [EC:2.3.3.1]
NCTC10271_02826  acnA; aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
NCTC10271_04871  fadI; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_00484  pcaF_1; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_00497  fadA_1; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NCTC10271_00530  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_00701  fadA_2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_00835  bktB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_00895  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_01067  pcaF_3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_01397  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_01567  fadA_5; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_01583  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_02520  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_03598  paaJ; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_03610  thlA_2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC10271_03584  Thiolase [KO:K00626] [EC:2.3.1.9]
NCTC10271_01396  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
NCTC10271_03883  accC; carbamoyl-phosphate synthase subunit L [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
NCTC10271_03878  accD5_3; carboxyl transferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
NCTC10271_03879  acetyl-/propionyl-coenzyme A carboxylase AccE5 [KO:K27095]
NCTC10271_01897  accD5_2; propionyl-CoA carboxylase [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
NCTC10271_02810  mutB; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
NCTC10271_02811  mutA; methylmalonyl-CoA mutase, heterodimeric type, beta chain [KO:K01847] [EC:5.4.99.2]
NCTC10271_01453  scpA_2; cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
NCTC10271_01452  scpA_1; methylmalonyl-CoA mutase large subunit [KO:K01848] [EC:5.4.99.2]
NCTC10271_01273  FAD/FMN-dependent dehydrogenase [KO:K00104] [EC:1.1.99.14]
NCTC10271_04074  katE_1; catalase KatE [KO:K03781] [EC:1.11.1.6]
NCTC10271_05094  katE_2; catalase [KO:K03781] [EC:1.11.1.6]
NCTC10271_01914  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
NCTC10271_01962  glnA_1; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
NCTC10271_01968  glnA_2; L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NCTC10271_03234  glnA_3; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NCTC10271_01089  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NCTC10271_02553  gcvP; glycine dehydrogenase, decarboxylating [KO:K00281] [EC:1.4.4.2]
NCTC10271_01980  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
NCTC10271_04514  lpd; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
NCTC10271_02558  gcvH; glycine cleavage system H protein [KO:K02437]
NCTC10271_03299  glxK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
NCTC10271_04214  dmlA; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NCTC10271_01260  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
NCTC10271_04299  fdoG; formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
NCTC10271_04298  fdnH; Fe-S-cluster-containing hydrogenase subunit [KO:K00124]
NCTC10271_03615  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mflv00010  Glycolysis / Gluconeogenesis
mflv00020  Citrate cycle (TCA cycle)
mflv00030  Pentose phosphate pathway
mflv00053  Ascorbate and aldarate metabolism
mflv00071  Fatty acid degradation
mflv00230  Purine metabolism
mflv00250  Alanine, aspartate and glutamate metabolism
mflv00260  Glycine, serine and threonine metabolism
mflv00620  Pyruvate metabolism
mflv00710  Carbon fixation by Calvin cycle
mflv00750  Vitamin B6 metabolism
mflv00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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