KEGG   PATHWAY: mgad00630
Entry
mgad00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium gadium
Class
Metabolism; Carbohydrate metabolism
Pathway map
mgad00630  Glyoxylate and dicarboxylate metabolism
mgad00630

Module
mgad_M00012  Glyoxylate cycle [PATH:mgad00630]
mgad_M00621  Glycine cleavage system [PATH:mgad00630]
mgad_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mgad00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium gadium [GN:mgad]
Gene
MGAD_09210  aceA_1; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MGAD_48940  aceA_2; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MGAD_22500  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MGAD_38600  hypothetical protein [KO:K01895] [EC:6.2.1.1]
MGAD_07620  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MGAD_54190  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MGAD_34590  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
MGAD_34620  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MGAD_11780  acnA; aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
MGAD_07930  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_19900  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_22930  transporter [KO:K00626] [EC:2.3.1.9]
MGAD_29970  putative acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MGAD_32900  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_33850  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_35050  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_36910  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_37270  fadA5; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_37410  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_45720  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_55580  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MGAD_55570  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MGAD_25460  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MGAD_25400  propionyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MGAD_25410  hypothetical protein [KO:K27095]
MGAD_02930  propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MGAD_11600  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MGAD_11610  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MGAD_56040  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MGAD_56030  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MGAD_54390  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
MGAD_39130  catalase [KO:K03781] [EC:1.11.1.6]
MGAD_03810  5'-nucleotidase [KO:K01091] [EC:3.1.3.18]
MGAD_46110  cbbL; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit [KO:K01601] [EC:4.1.1.39]
MGAD_46120  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
MGAD_04040  glnA_1; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MGAD_04120  glnA_2; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MGAD_08360  glnA_3; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MGAD_16420  glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MGAD_39230  glnT; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MGAD_58450  glnN; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MGAD_29730  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MGAD_07580  gcvP; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MGAD_04230  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MGAD_48890  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MGAD_07530  gcvH; glycine cleavage system H protein [KO:K02437]
MGAD_58660  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
MGAD_17130  glycerate kinase [KO:K00865] [EC:2.7.1.165]
MGAD_29240  ttuC; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
MGAD_54240  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MGAD_36360  hypothetical oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
MGAD_41230  cupin [KO:K01569] [EC:4.1.1.2]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mgad00010  Glycolysis / Gluconeogenesis
mgad00020  Citrate cycle (TCA cycle)
mgad00030  Pentose phosphate pathway
mgad00053  Ascorbate and aldarate metabolism
mgad00071  Fatty acid degradation
mgad00230  Purine metabolism
mgad00250  Alanine, aspartate and glutamate metabolism
mgad00260  Glycine, serine and threonine metabolism
mgad00620  Pyruvate metabolism
mgad00710  Carbon fixation by Calvin cycle
mgad00750  Vitamin B6 metabolism
mgad00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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