KEGG   PATHWAY: mhas00630
Entry
mhas00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium hassiacum
Class
Metabolism; Carbohydrate metabolism
Pathway map
mhas00630  Glyoxylate and dicarboxylate metabolism
mhas00630

Module
mhas_M00012  Glyoxylate cycle [PATH:mhas00630]
mhas_M00621  Glycine cleavage system [PATH:mhas00630]
mhas_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mhas00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium hassiacum [GN:mhas]
Gene
MHAS_04829  icl1; Isocitrate lyase 1 [KO:K01637] [EC:4.1.3.1]
MHAS_01915  aceAb; Isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1]
MHAS_03864  acsA_3; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MHAS_04030  acsA_4; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MHAS_04054  acsA_5; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MHAS_01811  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
MHAS_02813  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MHAS_03499  gltA2; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MHAS_03503  citA; Putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MHAS_02118  acnA; Aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
MHAS_03546  fadA_9; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
MHAS_03250  fadA_8; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MHAS_03709  hypothetical protein [KO:K00626] [EC:2.3.1.9]
MHAS_03740  fadA5_1; Steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MHAS_03761  pcaF_3; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MHAS_04290  pcaF_4; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MHAS_04577  fadI_4; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MHAS_03379  hypothetical protein [KO:K00626] [EC:2.3.1.9]
MHAS_00806  thlA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MHAS_01837  hypothetical protein [KO:K00626] [EC:2.3.1.9]
MHAS_03069  pcaF_1; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MHAS_02681  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MHAS_03022  hypothetical protein [KO:K00626] [EC:2.3.1.9]
MHAS_02682  hypothetical protein [KO:K05606] [EC:5.1.99.1]
MHAS_00484  accA1_1; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MHAS_00490  accD5_1; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MHAS_00489  hypothetical protein [KO:K27095]
MHAS_01447  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MHAS_02102  mutB; putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MHAS_02103  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MHAS_02645  Pivalyl-CoA mutase small subunit [KO:K01849] [EC:5.4.99.2]
MHAS_02646  scpA_2; Methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MHAS_02793  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
MHAS_01937  katE; Catalase HPII [KO:K03781] [EC:1.11.1.6]
MHAS_01465  5'-nucleotidase [KO:K01091] [EC:3.1.3.18]
MHAS_02449  ipuC_2; Glutamate--isopropylamine ligase [KO:K01915] [EC:6.3.1.2]
MHAS_00066  Glutamate--methylamine ligase [KO:K01915] [EC:6.3.1.2]
MHAS_01335  ipuC_1; Glutamate--isopropylamine ligase [KO:K01915] [EC:6.3.1.2]
MHAS_00121  Glutamate--methylamine ligase [KO:K01915] [EC:6.3.1.2]
MHAS_01480  glnA_1; Glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MHAS_01485  glnA_2; Glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MHAS_01859  glnA_3; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MHAS_03922  Glutamate--methylamine ligase [KO:K01915] [EC:6.3.1.2]
MHAS_03228  glyA; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MHAS_01808  gcvP; putative glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MHAS_01948  gcvT_2; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MHAS_01497  gcvT_1; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MHAS_04823  lpdC; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MHAS_01803  gcvH; Glycine cleavage system H protein [KO:K02437]
MHAS_00116  garR_1; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
MHAS_02537  garK; Glycerate 2-kinase [KO:K00865] [EC:2.7.1.165]
MHAS_02805  kgd; Multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MHAS_00801  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mhas00010  Glycolysis / Gluconeogenesis
mhas00020  Citrate cycle (TCA cycle)
mhas00030  Pentose phosphate pathway
mhas00071  Fatty acid degradation
mhas00230  Purine metabolism
mhas00250  Alanine, aspartate and glutamate metabolism
mhas00260  Glycine, serine and threonine metabolism
mhas00620  Pyruvate metabolism
mhas00710  Carbon fixation by Calvin cycle
mhas00750  Vitamin B6 metabolism
mhas00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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