KEGG   PATHWAY: mhaw00630
Entry
mhaw00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Micromonospora halotolerans
Class
Metabolism; Carbohydrate metabolism
Pathway map
mhaw00630  Glyoxylate and dicarboxylate metabolism
mhaw00630

Module
mhaw_M00621  Glycine cleavage system [PATH:mhaw00630]
Other DBs
GO: 0046487 0043648
Organism
Micromonospora halotolerans [GN:mhaw]
Gene
RMN56_09565  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
RMN56_26165  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
RMN56_22980  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
RMN56_16000  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
RMN56_31830  citrate synthase [KO:K01647] [EC:2.3.3.1]
RMN56_09005  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
RMN56_22000  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
RMN56_07100  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RMN56_10655  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RMN56_17365  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RMN56_17350  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
RMN56_17265  protein meaA [KO:K14447] [EC:5.4.99.63]
RMN56_07520  biotin carboxylase N-terminal domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
RMN56_07435  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
RMN56_07610  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
RMN56_14050  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
RMN56_22985  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
RMN56_10055  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
RMN56_22990  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
RMN56_22995  heterodisulfide reductase-related iron-sulfur binding cluster [KO:K11473] [EC:1.1.99.14]
RMN56_01890  catalase [KO:K03781] [EC:1.11.1.6]
RMN56_09085  haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
RMN56_02300  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
RMN56_04160  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RMN56_19930  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
RMN56_19995  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
RMN56_17160  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RMN56_24550  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RMN56_26700  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
RMN56_20140  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
RMN56_20125  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
RMN56_26640  gcvH; glycine cleavage system protein GcvH [KO:K02437]
RMN56_30390  glycerate kinase [KO:K00865] [EC:2.7.1.165]
RMN56_20225  glycerate kinase [KO:K00865] [EC:2.7.1.165]
RMN56_28315  isocitrate/isopropylmalate dehydrogenase family protein [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RMN56_24050  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RMN56_26070  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RMN56_16765  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
RMN56_26530  fdh; formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
RMN56_26535  4Fe-4S dicluster domain-containing protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mhaw00010  Glycolysis / Gluconeogenesis
mhaw00020  Citrate cycle (TCA cycle)
mhaw00030  Pentose phosphate pathway
mhaw00053  Ascorbate and aldarate metabolism
mhaw00071  Fatty acid degradation
mhaw00230  Purine metabolism
mhaw00250  Alanine, aspartate and glutamate metabolism
mhaw00260  Glycine, serine and threonine metabolism
mhaw00620  Pyruvate metabolism
mhaw00710  Carbon fixation by Calvin cycle
mhaw00750  Vitamin B6 metabolism
mhaw00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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