KEGG   PATHWAY: mlj00630
Entry
mlj00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium lacus
Class
Metabolism; Carbohydrate metabolism
Pathway map
mlj00630  Glyoxylate and dicarboxylate metabolism
mlj00630

Module
mlj_M00012  Glyoxylate cycle [PATH:mlj00630]
mlj_M00621  Glycine cleavage system [PATH:mlj00630]
mlj_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mlj00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium lacus [GN:mlj]
Gene
MLAC_18920  aceA_1; isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1]
MLAC_36900  aceA_2; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MLAC_23520  acsA_1; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MLAC_46300  acsA_2; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MLAC_17790  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MLAC_08660  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MLAC_03800  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MLAC_03860  gltA2; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MLAC_07220  prpC; 2-methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
MLAC_13420  acn; aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
MLAC_00200  ltp3_1; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_03420  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_04090  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_06350  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_09900  fadA4; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_10170  hypothetical protein [KO:K00626] [EC:2.3.1.9]
MLAC_18100  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_39440  fadA2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_47520  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_47620  fadA5; steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MLAC_47920  ltp3_2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MLAC_09890  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MLAC_32480  accA3; acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MLAC_32400  accD5; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MLAC_32410  hypothetical protein [KO:K27095]
MLAC_22610  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MLAC_13640  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MLAC_13650  mutB; putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MLAC_01950  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MLAC_01940  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MLAC_08870  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MLAC_22980  dehydrogenase [KO:K00104] [EC:1.1.99.14]
MLAC_22460  hypothetical protein [KO:K01091] [EC:3.1.3.18]
MLAC_18330  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MLAC_22300  glnA1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MLAC_22340  glnA2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MLAC_27950  glnA4; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MLAC_06550  glyA1; serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
MLAC_41660  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
MLAC_17760  gcvP; putative glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MLAC_22200  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MLAC_36950  lpdC; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MLAC_17710  gcvH; glycine cleavage system H protein [KO:K02437]
MLAC_22140  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MLAC_08740  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MLAC_28960  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
MLAC_41150  oxcA; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mlj00010  Glycolysis / Gluconeogenesis
mlj00020  Citrate cycle (TCA cycle)
mlj00030  Pentose phosphate pathway
mlj00053  Ascorbate and aldarate metabolism
mlj00071  Fatty acid degradation
mlj00230  Purine metabolism
mlj00250  Alanine, aspartate and glutamate metabolism
mlj00260  Glycine, serine and threonine metabolism
mlj00620  Pyruvate metabolism
mlj00710  Carbon fixation by Calvin cycle
mlj00750  Vitamin B6 metabolism
mlj00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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