KEGG   PATHWAY: mlw00630
Entry
mlw00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium lentiflavum
Class
Metabolism; Carbohydrate metabolism
Pathway map
mlw00630  Glyoxylate and dicarboxylate metabolism
mlw00630

Module
mlw_M00012  Glyoxylate cycle [PATH:mlw00630]
mlw_M00621  Glycine cleavage system [PATH:mlw00630]
mlw_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mlw00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium lentiflavum [GN:mlw]
Gene
MJO58_03705  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MJO58_14275  aceA; isocitrate lyase ICL2 [KO:K01637] [EC:4.1.3.1]
MJO58_15265  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MJO58_25580  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MJO58_13775  malate synthase G [KO:K01638] [EC:2.3.3.9]
MJO58_20675  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MJO58_21270  bifunctional 2-methylcitrate synthase/citrate synthase [KO:K01647] [EC:2.3.3.1]
MJO58_23155  citrate synthase [KO:K01647] [EC:2.3.3.1]
MJO58_23165  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MJO58_11420  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MJO58_02355  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_07855  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_13890  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_19895  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_20050  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_21575  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_22800  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_23065  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_23345  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_24840  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
MJO58_24955  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MJO58_25015  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MJO58_13130  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MJO58_20055  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MJO58_06065  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MJO58_06090  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MJO58_06085  acyl-CoA carboxylase subunit epsilon [KO:K27095]
MJO58_16840  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MJO58_11515  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MJO58_11520  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MJO58_23965  cobalamin-dependent protein [KO:K01849] [EC:5.4.99.2]
MJO58_23970  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
MJO58_17045  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
MJO58_20605  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
MJO58_00885  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
MJO58_25965  catalase [KO:K03781] [EC:1.11.1.6]
MJO58_10375  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
MJO58_16710  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
MJO58_07430  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MJO58_12815  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
MJO58_14005  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MJO58_16590  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MJO58_16630  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MJO58_21495  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MJO58_13755  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
MJO58_16525  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
MJO58_03680  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MJO58_13730  gcvH; glycine cleavage system protein GcvH [KO:K02437]
MJO58_16495  glycerate kinase [KO:K00865] [EC:2.7.1.165]
MJO58_20650  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MJO58_00820  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
MJO58_00825  4Fe-4S dicluster domain-containing protein [KO:K00124]
MJO58_01440  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mlw00010  Glycolysis / Gluconeogenesis
mlw00020  Citrate cycle (TCA cycle)
mlw00030  Pentose phosphate pathway
mlw00053  Ascorbate and aldarate metabolism
mlw00071  Fatty acid degradation
mlw00230  Purine metabolism
mlw00250  Alanine, aspartate and glutamate metabolism
mlw00260  Glycine, serine and threonine metabolism
mlw00620  Pyruvate metabolism
mlw00710  Carbon fixation by Calvin cycle
mlw00750  Vitamin B6 metabolism
mlw00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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