KEGG   PATHWAY: mman00630
Entry
mman00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium mantenii
Class
Metabolism; Carbohydrate metabolism
Pathway map
mman00630  Glyoxylate and dicarboxylate metabolism
mman00630

Module
mman_M00012  Glyoxylate cycle [PATH:mman00630]
mman_M00621  Glycine cleavage system [PATH:mman00630]
mman_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mman00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium mantenii [GN:mman]
Gene
MMAN_12880  aceA_1; isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1]
MMAN_34000  aceA_2; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MMAN_14120  acsA_1; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MMAN_47000  acsA_3; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MMAN_11790  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MMAN_27120  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MMAN_45550  citrate synthase [KO:K01647] [EC:2.3.3.1]
MMAN_51890  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MMAN_51910  gltA2; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MMAN_07110  acn; aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
MMAN_17780  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MMAN_20830  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MMAN_25660  fadA4; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_36440  fadA2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_12140  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_21510  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_25350  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_41100  atoB_1; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_41140  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_41460  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_41860  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_48090  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_48210  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_48420  ltp3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_51440  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_52090  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_52820  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_54300  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_57610  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MMAN_10540  transporter [KO:K00626] [EC:2.3.1.9]
MMAN_25670  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MMAN_29250  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MMAN_29200  accD5; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MMAN_29210  hypothetical protein [KO:K27095]
MMAN_18040  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MMAN_07350  mutB; putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MMAN_07340  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MMAN_50150  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MMAN_50140  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MMAN_18670  dehydrogenase [KO:K00104] [EC:1.1.99.14]
MMAN_26620  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MMAN_04860  srpA; catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MMAN_39430  catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MMAN_46260  katA; catalase [KO:K03781] [EC:1.11.1.6]
MMAN_55910  catalase [KO:K03781] [EC:1.11.1.6]
MMAN_17830  hypothetical protein [KO:K01091] [EC:3.1.3.18]
MMAN_02330  glnA4; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MMAN_12360  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MMAN_17550  glnA1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MMAN_17610  glnA2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MMAN_54470  glyA1; serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
MMAN_11750  gcvP; putative glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MMAN_17430  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MMAN_34050  lpd; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MMAN_11700  gcvH; glycine cleavage system H protein [KO:K02437]
MMAN_17370  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MMAN_27070  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MMAN_36540  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MMAN_46500  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MMAN_46490  dehydrogenase [KO:K00123] [EC:1.17.1.9]
MMAN_46510  4Fe-4S ferredoxin [KO:K00124]
MMAN_38400  oxcA; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mman00010  Glycolysis / Gluconeogenesis
mman00020  Citrate cycle (TCA cycle)
mman00030  Pentose phosphate pathway
mman00053  Ascorbate and aldarate metabolism
mman00071  Fatty acid degradation
mman00230  Purine metabolism
mman00250  Alanine, aspartate and glutamate metabolism
mman00260  Glycine, serine and threonine metabolism
mman00620  Pyruvate metabolism
mman00710  Carbon fixation by Calvin cycle
mman00750  Vitamin B6 metabolism
mman00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system