KEGG   PATHWAY: mmuc00630
Entry
mmuc00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium mucogenicum
Class
Metabolism; Carbohydrate metabolism
Pathway map
mmuc00630  Glyoxylate and dicarboxylate metabolism
mmuc00630

Module
mmuc_M00621  Glycine cleavage system [PATH:mmuc00630]
mmuc_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mmuc00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium mucogenicum [GN:mmuc]
Gene
C1S78_015160  isocitrate lyase family protein [KO:K01637] [EC:4.1.3.1]
C1S78_024140  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
C1S78_026615  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
C1S78_003650  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
C1S78_015645  malate synthase G [KO:K01638] [EC:2.3.3.9]
C1S78_025880  bifunctional 2-methylcitrate synthase/citrate synthase [KO:K01647] [EC:2.3.3.1]
C1S78_003565  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
C1S78_003585  citrate synthase [KO:K01647] [EC:2.3.3.1]
C1S78_013615  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
C1S78_015510  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_018020  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_019500  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_025185  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
C1S78_025355  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
C1S78_025460  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_001145  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_003360  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_003760  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
C1S78_004045  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_004055  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_004080  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_004320  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_005150  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_006925  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C1S78_006920  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
C1S78_004405  acetyl/propionyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
C1S78_020710  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
C1S78_009085  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
C1S78_013685  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
C1S78_013690  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
C1S78_018690  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
C1S78_018695  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
C1S78_016000  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
C1S78_006400  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
C1S78_012720  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
C1S78_012740  catalase [KO:K03781] [EC:1.11.1.6]
C1S78_009260  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
C1S78_014930  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
C1S78_021870  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
C1S78_029180  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C1S78_008290  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C1S78_009425  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
C1S78_009460  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
C1S78_022375  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C1S78_005290  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C1S78_014115  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C1S78_015655  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
C1S78_014100  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
C1S78_009520  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
C1S78_014105  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
C1S78_024170  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C1S78_014130  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C1S78_015680  gcvH; glycine cleavage system protein GcvH [KO:K02437]
C1S78_014110  gcvH; glycine cleavage system protein GcvH [KO:K02437]
C1S78_009550  glycerate kinase [KO:K00865] [EC:2.7.1.165]
C1S78_006280  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
C1S78_010410  cupin domain-containing protein [KO:K01569] [EC:4.1.1.2]
C1S78_014755  cupin domain-containing protein [KO:K01569] [EC:4.1.1.2]
C1S78_017310  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
C1S78_011255  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mmuc00010  Glycolysis / Gluconeogenesis
mmuc00020  Citrate cycle (TCA cycle)
mmuc00030  Pentose phosphate pathway
mmuc00053  Ascorbate and aldarate metabolism
mmuc00071  Fatty acid degradation
mmuc00230  Purine metabolism
mmuc00250  Alanine, aspartate and glutamate metabolism
mmuc00260  Glycine, serine and threonine metabolism
mmuc00620  Pyruvate metabolism
mmuc00750  Vitamin B6 metabolism
mmuc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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