KEGG   PATHWAY: mpae00630
Entry
mpae00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium pallens
Class
Metabolism; Carbohydrate metabolism
Pathway map
mpae00630  Glyoxylate and dicarboxylate metabolism
mpae00630

Module
mpae_M00621  Glycine cleavage system [PATH:mpae00630]
mpae_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mpae00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium pallens [GN:mpae]
Gene
K0O64_03500  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
K0O64_16610  aceA; isocitrate lyase ICL2 [KO:K01637] [EC:4.1.3.1]
K0O64_11950  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
K0O64_26525  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
K0O64_16160  malate synthase G [KO:K01638] [EC:2.3.3.9]
K0O64_24270  citrate synthase [KO:K01647] [EC:2.3.3.1]
K0O64_24295  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
K0O64_13380  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
K0O64_01620  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_05815  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_15930  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_21315  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_21400  thiolase family protein [KO:K00626] [EC:2.3.1.9]
K0O64_21880  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_23710  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_24010  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_24475  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_24750  thiolase family protein [KO:K00626] [EC:2.3.1.9]
K0O64_24810  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_25780  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
K0O64_25915  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
K0O64_25980  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K0O64_07020  thiolase family protein [KO:K00626] [EC:2.3.1.9]
K0O64_21885  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
K0O64_07315  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
K0O64_07350  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K0O64_07345  acyl-CoA carboxylase subunit epsilon [KO:K27095]
K0O64_18635  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K0O64_13455  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
K0O64_13460  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
K0O64_21650  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
K0O64_21655  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
K0O64_20715  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K0O64_22400  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K0O64_04160  catalase [KO:K03781] [EC:1.11.1.6]
K0O64_12550  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
K0O64_26880  catalase [KO:K03781] [EC:1.11.1.6]
K0O64_18450  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
K0O64_09700  form I ribulose bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
K0O64_09705  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
K0O64_10720  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K0O64_15810  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K0O64_18325  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K0O64_18355  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K0O64_18900  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K0O64_19375  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K0O64_19760  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
K0O64_26925  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K0O64_05925  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K0O64_16175  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
K0O64_18265  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
K0O64_03470  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
K0O64_16200  gcvH; glycine cleavage system protein GcvH [KO:K02437]
K0O64_19685  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
K0O64_18230  glycerate kinase [KO:K00865] [EC:2.7.1.165]
K0O64_22545  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K0O64_11755  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
K0O64_11760  4Fe-4S dicluster domain-containing protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mpae00010  Glycolysis / Gluconeogenesis
mpae00020  Citrate cycle (TCA cycle)
mpae00030  Pentose phosphate pathway
mpae00053  Ascorbate and aldarate metabolism
mpae00071  Fatty acid degradation
mpae00230  Purine metabolism
mpae00250  Alanine, aspartate and glutamate metabolism
mpae00260  Glycine, serine and threonine metabolism
mpae00620  Pyruvate metabolism
mpae00710  Carbon fixation by Calvin cycle
mpae00750  Vitamin B6 metabolism
mpae00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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