KEGG   PATHWAY: mphu00630
Entry
mphu00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium phocaicum
Class
Metabolism; Carbohydrate metabolism
Pathway map
mphu00630  Glyoxylate and dicarboxylate metabolism
mphu00630

Module
mphu_M00621  Glycine cleavage system [PATH:mphu00630]
mphu_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mphu00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium phocaicum [GN:mphu]
Gene
MPHO_46270  isocitrate lyase (AceA) [KO:K01637] [EC:4.1.3.1]
MPHO_06330  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MPHO_29300  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
MPHO_41900  hypothetical protein [KO:K01895] [EC:6.2.1.1]
MPHO_05370  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MPHO_29430  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
MPHO_29470  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MPHO_42760  gltA1; citrate synthase [KO:K01647] [EC:2.3.3.1]
MPHO_09190  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MPHO_43870  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_44200  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_56170  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_00750  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_05650  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_22890  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_26390  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_28030  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_29950  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_31300  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_34000  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MPHO_43650  putative acetyl-CoA acetyltransferase FadA [KO:K00626] [EC:2.3.1.9]
MPHO_22900  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MPHO_53740  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MPHO_53910  propionyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MPHO_53900  hypothetical protein [KO:K27095]
MPHO_18710  propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MPHO_09030  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MPHO_09040  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MPHO_04700  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
MPHO_23930  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
MPHO_11020  catalase [KO:K03781] [EC:1.11.1.6]
MPHO_11070  catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MPHO_21780  catalase [KO:K03781] [EC:1.11.1.6]
MPHO_18280  5'-nucleotidase [KO:K01091] [EC:3.1.3.18]
MPHO_06810  glnN; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MPHO_17930  glnA_1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MPHO_17990  glnA_2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MPHO_20170  glnA_3; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MPHO_26080  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MPHO_05350  gcvP; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MPHO_17750  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MPHO_46160  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MPHO_05300  gcvH; glycine cleavage system H protein [KO:K02437]
MPHO_17690  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MPHO_24110  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MPHO_07120  cupin [KO:K01569] [EC:4.1.1.2]
MPHO_15960  hypothetical oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
MPHO_02250  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
MPHO_14050  formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mphu00010  Glycolysis / Gluconeogenesis
mphu00020  Citrate cycle (TCA cycle)
mphu00030  Pentose phosphate pathway
mphu00053  Ascorbate and aldarate metabolism
mphu00071  Fatty acid degradation
mphu00230  Purine metabolism
mphu00250  Alanine, aspartate and glutamate metabolism
mphu00260  Glycine, serine and threonine metabolism
mphu00620  Pyruvate metabolism
mphu00710  Carbon fixation by Calvin cycle
mphu00750  Vitamin B6 metabolism
mphu00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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