KEGG   PATHWAY: msen00630
Entry
msen00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium senegalense
Class
Metabolism; Carbohydrate metabolism
Pathway map
msen00630  Glyoxylate and dicarboxylate metabolism
msen00630

Module
msen_M00012  Glyoxylate cycle [PATH:msen00630]
msen_M00621  Glycine cleavage system [PATH:msen00630]
msen_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:msen00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium senegalense [GN:msen]
Gene
K3U95_14285  aceA; isocitrate lyase ICL2 [KO:K01637] [EC:4.1.3.1]
K3U95_04505  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
K3U95_23755  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
K3U95_26350  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
K3U95_14020  malate synthase G [KO:K01638] [EC:2.3.3.9]
K3U95_20600  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
K3U95_09935  bifunctional 2-methylcitrate synthase/citrate synthase [KO:K01647] [EC:2.3.3.1]
K3U95_23870  citrate synthase [KO:K01647] [EC:2.3.3.1]
K3U95_23890  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
K3U95_01960  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
K3U95_11965  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
K3U95_05155  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
K3U95_08680  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_13865  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_19175  thiolase family protein [KO:K00626] [EC:2.3.1.9]
K3U95_19240  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_22060  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_23085  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_24115  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_25025  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
K3U95_25230  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
K3U95_25315  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_01555  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K3U95_08675  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
K3U95_20590  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
K3U95_20545  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K3U95_20550  acyl-CoA carboxylase subunit epsilon [KO:K27095]
K3U95_16005  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K3U95_12035  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
K3U95_12040  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
K3U95_08965  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
K3U95_08960  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
K3U95_20930  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K3U95_01380  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K3U95_11590  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
K3U95_02240  catalase [KO:K03781] [EC:1.11.1.6]
K3U95_07255  catalase [KO:K03781] [EC:1.11.1.6]
K3U95_15845  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
K3U95_13700  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K3U95_15725  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K3U95_15755  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K3U95_17575  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K3U95_26860  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K3U95_02290  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K3U95_06955  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K3U95_21925  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K3U95_14030  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
K3U95_15665  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
K3U95_04480  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
K3U95_14055  gcvH; glycine cleavage system protein GcvH [KO:K02437]
K3U95_17855  glycerate kinase [KO:K00865] [EC:2.7.1.165]
K3U95_02545  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
K3U95_21015  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K3U95_19280  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
K3U95_02065  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
K3U95_16275  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
msen00010  Glycolysis / Gluconeogenesis
msen00020  Citrate cycle (TCA cycle)
msen00030  Pentose phosphate pathway
msen00053  Ascorbate and aldarate metabolism
msen00071  Fatty acid degradation
msen00230  Purine metabolism
msen00250  Alanine, aspartate and glutamate metabolism
msen00260  Glycine, serine and threonine metabolism
msen00620  Pyruvate metabolism
msen00710  Carbon fixation by Calvin cycle
msen00750  Vitamin B6 metabolism
msen00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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