KEGG   PATHWAY: msp00630
Entry
msp00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium gilvum Spyr1
Class
Metabolism; Carbohydrate metabolism
Pathway map
msp00630  Glyoxylate and dicarboxylate metabolism
msp00630

Module
msp_M00012  Glyoxylate cycle [PATH:msp00630]
msp_M00621  Glycine cleavage system [PATH:msp00630]
msp_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:msp00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium gilvum Spyr1 [GN:msp]
Gene
Mspyr1_06760  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Mspyr1_25880  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Mspyr1_42820  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Mspyr1_47930  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Mspyr1_44010  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Mspyr1_26980  malate synthase G [KO:K01638] [EC:2.3.3.9]
Mspyr1_26700  malate dehydrogenase (NAD) [KO:K00024] [EC:1.1.1.37]
Mspyr1_11120  citrate synthase [KO:K01647] [EC:2.3.3.1]
Mspyr1_11150  citrate synthase [KO:K01647] [EC:2.3.3.1]
Mspyr1_30110  aconitase [KO:K01681] [EC:4.2.1.3]
Mspyr1_17730  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_26710  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_19320  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_12690  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_14640  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_11920  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_03430  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Mspyr1_10730  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_48300  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_08910  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_09200  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_46830  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_37170  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mspyr1_17720  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Mspyr1_41930  acetyl/propionyl-CoA carboxylase, alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Mspyr1_41830  acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
Mspyr1_41840  hypothetical protein [KO:K27095]
Mspyr1_22150  acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Mspyr1_29930  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Mspyr1_29940  methylmalonyl-CoA mutase, heterodimeric type, beta chain [KO:K01847] [EC:5.4.99.2]
Mspyr1_18200  methylmalonyl-CoA mutase family protein [KO:K01849] [EC:5.4.99.2]
Mspyr1_18190  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
Mspyr1_16620  FAD/FMN-dependent dehydrogenase [KO:K00104] [EC:1.1.99.14]
Mspyr1_27830  catalase [KO:K03781] [EC:1.11.1.6]
Mspyr1_48710  catalase [KO:K03781] [EC:1.11.1.6]
Mspyr1_22320  haloacid dehalogenase superfamily enzyme, subfamily IA [KO:K01091] [EC:3.1.3.18]
Mspyr1_34100  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mspyr1_20310  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mspyr1_26470  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mspyr1_22530  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mspyr1_22590  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mspyr1_48790  glutamine synthetase, type III [KO:K01915] [EC:6.3.1.2]
Mspyr1_14840  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Mspyr1_27290  glycine dehydrogenase, decarboxylating [KO:K00281] [EC:1.4.4.2]
Mspyr1_22710  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Mspyr1_45540  glycine cleavage system T protein (aminomethyltransferase) [KO:K00605] [EC:2.1.2.10]
Mspyr1_06690  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Mspyr1_27350  glycine cleavage system H protein [KO:K02437]
Mspyr1_20390  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Mspyr1_22760  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Mspyr1_16500  2-oxoglutarate dehydrogenase E1 component [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Mspyr1_16820  anaerobic dehydrogenase, typically selenocysteine-containing [KO:K00122] [EC:1.17.1.9]
Mspyr1_45090  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
msp00010  Glycolysis / Gluconeogenesis
msp00020  Citrate cycle (TCA cycle)
msp00030  Pentose phosphate pathway
msp00053  Ascorbate and aldarate metabolism
msp00071  Fatty acid degradation
msp00230  Purine metabolism
msp00250  Alanine, aspartate and glutamate metabolism
msp00260  Glycine, serine and threonine metabolism
msp00620  Pyruvate metabolism
msp00710  Carbon fixation by Calvin cycle
msp00750  Vitamin B6 metabolism
msp00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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