KEGG   PATHWAY: nbr00630
Entry
nbr00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nocardia brasiliensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
nbr00630  Glyoxylate and dicarboxylate metabolism
nbr00630

Module
nbr_M00012  Glyoxylate cycle [PATH:nbr00630]
nbr_M00621  Glycine cleavage system [PATH:nbr00630]
nbr_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nbr00630]
Other DBs
GO: 0046487 0043648
Organism
Nocardia brasiliensis [GN:nbr]
Gene
O3I_039170  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
O3I_001830  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
O3I_011910  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
O3I_031205  putative acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
O3I_017990  malate synthase G [KO:K01638] [EC:2.3.3.9]
O3I_028540  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
O3I_003695  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
O3I_003710  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
O3I_020485  excisionase family DNA binding domain-containing protein [KO:K01647] [EC:2.3.3.1]
O3I_020490  Citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
O3I_033370  citrate synthase [KO:K01647] [EC:2.3.3.1]
O3I_027580  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
O3I_001380  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_002800  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_002865  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_002885  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_014020  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_014030  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_006345  acyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_003935  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_014315  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_036515  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_040660  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_040580  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
O3I_006340  hypothetical protein [KO:K05606] [EC:5.1.99.1]
O3I_005780  acetyl-CoA carboxylase, biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
O3I_005805  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
O3I_005800  hypothetical protein [KO:K27095]
O3I_010910  Propionyl-CoA carboxylase beta subunit [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
O3I_019700  methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
O3I_019705  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
O3I_015485  methylaspartate mutase E chain family protein [KO:K19268] [EC:5.4.99.1]
O3I_015470  B12 binding domain protein [KO:K01846] [EC:5.4.99.1]
O3I_005895  putative oxidoreductase [KO:K00104] [EC:1.1.99.14]
O3I_023640  fad linked oxidase domain-containing protein [KO:K00104] [EC:1.1.99.14]
O3I_001640  catalase [KO:K03781] [EC:1.11.1.6]
O3I_021945  catalase [KO:K03781] [EC:1.11.1.6]
O3I_032795  catalase [KO:K03781] [EC:1.11.1.6]
O3I_025995  hypothetical protein [KO:K01091] [EC:3.1.3.18]
O3I_030795  putative haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
O3I_010440  Serine-glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
O3I_011140  glutamine synthetase I [KO:K01915] [EC:6.3.1.2]
O3I_011220  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
O3I_019320  gamma-glutamylisopropylamide synthetase [KO:K01915] [EC:6.3.1.2]
O3I_009235  glutamine synthetase (glutamate--ammonia ligase) [KO:K01915] [EC:6.3.1.2]
O3I_032590  glutamine synthetase-like protein [KO:K01915] [EC:6.3.1.2]
O3I_018435  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
O3I_036320  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
O3I_017920  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
O3I_011335  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
O3I_019205  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
O3I_039495  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
O3I_017895  glycine cleavage system protein H [KO:K02437]
O3I_010455  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
O3I_016230  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
O3I_010465  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
O3I_016220  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
O3I_010460  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
O3I_016225  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
O3I_010450  glycerate kinase [KO:K00865] [EC:2.7.1.165]
O3I_016235  glycerate kinase [KO:K00865] [EC:2.7.1.165]
O3I_016280  glycerate kinase [KO:K00865] [EC:2.7.1.165]
O3I_040910  glycerate kinase [KO:K00865] [EC:2.7.1.165]
O3I_030435  Tartrate dehydrogenase/decarboxylase (TDH) (D-malate dehydrogenase [decarboxylating]) [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
O3I_016290  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
O3I_014760  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
O3I_013245  4-hydroxy-2-oxoglutarate/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
O3I_035540  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
O3I_022045  cupin [KO:K01569] [EC:4.1.1.2]
O3I_021165  arylformamidase [KO:K01432] [EC:3.5.1.9]
O3I_039030  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
O3I_035350  formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
nbr00010  Glycolysis / Gluconeogenesis
nbr00020  Citrate cycle (TCA cycle)
nbr00030  Pentose phosphate pathway
nbr00053  Ascorbate and aldarate metabolism
nbr00071  Fatty acid degradation
nbr00230  Purine metabolism
nbr00250  Alanine, aspartate and glutamate metabolism
nbr00260  Glycine, serine and threonine metabolism
nbr00620  Pyruvate metabolism
nbr00710  Carbon fixation by Calvin cycle
nbr00750  Vitamin B6 metabolism
nbr00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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