KEGG   PATHWAY: nno00630
Entry
nno00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nocardia nova
Class
Metabolism; Carbohydrate metabolism
Pathway map
nno00630  Glyoxylate and dicarboxylate metabolism
nno00630

Module
nno_M00012  Glyoxylate cycle [PATH:nno00630]
nno_M00621  Glycine cleavage system [PATH:nno00630]
nno_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nno00630]
Other DBs
GO: 0046487 0043648
Organism
Nocardia nova [GN:nno]
Gene
NONO_c70960  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
NONO_c03820  acsA1; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NONO_c17190  putative acyl--CoA ligase [KO:K01895] [EC:6.2.1.1]
NONO_c27820  acsA2; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
NONO_c28300  acsA3; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
NONO_c36000  acsA4; acetate--CoA ligase AcsA [KO:K01895] [EC:6.2.1.1]
NONO_c32160  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
NONO_c45650  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NONO_c07130  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
NONO_c07160  putative citrate synthase CitA [KO:K01647] [EC:2.3.3.1]
NONO_c22690  citrate synthase-like protein [KO:K01647] [EC:2.3.3.1]
NONO_c35980  prpC1; 2-methylcitrate synthase PrpC [KO:K01647] [EC:2.3.3.1]
NONO_c62590  prpC2; 2-methylcitrate synthase PrpC [KO:K01647] [EC:2.3.3.1]
NONO_c43680  putative aconitate hydratase [KO:K01681] [EC:4.2.1.3]
NONO_c41350  acnA; 2-methylaconitase [KO:K01681] [EC:4.2.1.3]
NONO_c02860  putative 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NONO_c05180  putative 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NONO_c05320  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c05350  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c12710  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c27650  bktB; beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
NONO_c26290  hypothetical protein [KO:K00626] [EC:2.3.1.9]
NONO_c28470  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c36090  putative acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c37230  enoyl-CoA hydratase/isomerase family protein [KO:K00626] [EC:2.3.1.9]
NONO_c33470  putative acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c38130  putative thiolase [KO:K00626] [EC:2.3.1.9]
NONO_c38180  putative acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c42070  putative 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NONO_c43860  putative acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c50460  putative thiolase [KO:K00626] [EC:2.3.1.9]
NONO_c50780  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NONO_c65720  putative 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NONO_c74120  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NONO_c12700  putative methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
NONO_c27420  hypothetical protein [KO:K05606] [EC:5.1.99.1]
NONO_c11500  acetyl-/propionyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
NONO_c10710  acetyl-/propionyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
NONO_c50500  acetyl-/propionyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
NONO_c11450  acetyl-/propionyl-CoA carboxylase beta chain [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
NONO_c11460  acetyl-/propionyl-CoA carboxylase epsilon subunit [KO:K27095]
NONO_c20810  putative propionyl-CoA carboxylase beta chain [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
NONO_c41040  mutB; methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
NONO_c41050  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
NONO_c41580  putative methylmalonyl-CoA mutase small subunit [KO:K01849] [EC:5.4.99.2]
NONO_c41590  putative methylmalonyl-CoA mutase large subunit [KO:K01848] [EC:5.4.99.2]
NONO_c11670  putative glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
NONO_c30740  putative FAD-binding oxidase [KO:K00104] [EC:1.1.99.14]
NONO_c51340  putative FAD/FMN-dependent dehydrogenase [KO:K00104] [EC:1.1.99.14]
NONO_c03180  katA1; catalase [KO:K03781] [EC:1.11.1.6]
NONO_c26410  katA2; catalase [KO:K03781] [EC:1.11.1.6]
NONO_c28740  hydrolase [KO:K01091] [EC:3.1.3.18]
NONO_c74960  putative hydrolase [KO:K01091] [EC:3.1.3.18]
NONO_c28110  putative phosphatase [KO:K01091] [EC:3.1.3.18]
NONO_c39830  rbcL; ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
NONO_c39820  rbcS; ribulose bisphosphate carboxylase small chain [KO:K01602] [EC:4.1.1.39]
NONO_c18270  putative glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NONO_c21660  glnA1; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NONO_c21850  glnA2; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NONO_c30310  putative glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NONO_c49660  glnA3; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NONO_c62640  glyA1; serine hydroxymethyltransferase GlyA [KO:K00600] [EC:2.1.2.1]
NONO_c65460  glyA2; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NONO_c31900  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
NONO_c22820  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
NONO_c51110  lpdA2; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NONO_c71260  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NONO_c31850  gcvH; glycine cleavage system H protein [KO:K02437]
NONO_c74670  glycerate kinase [KO:K00865] [EC:2.7.1.165]
NONO_c54820  tartrate dehydrogenase/decarboxylase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NONO_c63870  kgd; 2-oxoglutarate decarboxylase Kgd [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
NONO_c62000  alpha/beta hydrolase family protein [KO:K01432] [EC:3.5.1.9]
NONO_c70730  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
NONO_c22730  amdA; acetamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
nno00010  Glycolysis / Gluconeogenesis
nno00020  Citrate cycle (TCA cycle)
nno00030  Pentose phosphate pathway
nno00053  Ascorbate and aldarate metabolism
nno00071  Fatty acid degradation
nno00230  Purine metabolism
nno00250  Alanine, aspartate and glutamate metabolism
nno00260  Glycine, serine and threonine metabolism
nno00620  Pyruvate metabolism
nno00710  Carbon fixation by Calvin cycle
nno00750  Vitamin B6 metabolism
nno00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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