KEGG   PATHWAY: omy00630
Entry
omy00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Oncorhynchus mykiss (rainbow trout)
Class
Metabolism; Carbohydrate metabolism
Pathway map
omy00630  Glyoxylate and dicarboxylate metabolism
omy00630

Module
omy_M00621  Glycine cleavage system [PATH:omy00630]
omy_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:omy00630]
Other DBs
GO: 0046487 0043648
Organism
Oncorhynchus mykiss (rainbow trout) [GN:omy]
Gene
110509144  acetyl-coenzyme A synthetase, cytoplasmic-like [KO:K01895] [EC:6.2.1.1]
110522633  LOW QUALITY PROTEIN: acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
110530856  acss2l; acetyl-coenzyme A synthetase, cytoplasmic [KO:K01895] [EC:6.2.1.1]
110492305  acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
110532102  acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
110527513  acss1; acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
100136010  cmdg; malate dehydrogenase, cytoplasmic isoform X1 [KO:K00025] [EC:1.1.1.37]
110486012  malate dehydrogenase, cytoplasmic isoform X1 [KO:K00025] [EC:1.1.1.37]
110531764  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
118936590  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
110537548  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
110533583  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
110528253  citrate synthase, mitochondrial isoform X1 [KO:K01647] [EC:2.3.3.1]
110492108  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
110532556  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
110502871  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
110538366  aconitate hydratase, mitochondrial isoform X1 [KO:K01681] [EC:4.2.1.3]
110499095  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
110486418  aconitate hydratase, mitochondrial isoform X1 [KO:K01681] [EC:4.2.1.3]
110500623  aco1; cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
110522354  acat2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
110533684  acat1; acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
110506431  methylmalonyl-CoA epimerase, mitochondrial [KO:K05606] [EC:5.1.99.1]
110526316  mcee; methylmalonyl-CoA epimerase, mitochondrial isoform X1 [KO:K05606] [EC:5.1.99.1]
110495360  propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
110496964  propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
110495698  propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
110495699  propionyl-CoA carboxylase beta chain, mitochondrial isoform X1 [KO:K01966] [EC:6.4.1.3 2.1.3.15]
110529882  mut; methylmalonyl-CoA mutase, mitochondrial isoform X1 [KO:K01847] [EC:5.4.99.2]
110501666  hao2; hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
110505655  hao1; hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
110520413  hydroxyacid oxidase 2-like isoform X1 [KO:K11517] [EC:1.1.3.15]
110490868  cat; catalase isoform X1 [KO:K03781] [EC:1.11.1.6]
110486039  catalase [KO:K03781] [EC:1.11.1.6]
110493756  catalase [KO:K03781] [EC:1.11.1.6]
110488715  glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
110513528  glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
110504913  glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
110517888  glyoxylate reductase/hydroxypyruvate reductase isoform X1 [KO:K00049] [EC:1.1.1.79 1.1.1.81]
110499176  pgp; glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
110530082  agxtb; alanine--glyoxylate and serine--pyruvate aminotransferase b isoform X2 [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
110525913  agxta; alanine--glyoxylate and serine--pyruvate aminotransferase a isoform X1 [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
100135973  gs01; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
100135974  gs02; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
100135975  glulb; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
100136624  gs04; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
110523634  glutamine synthetase isoform X1 [KO:K01915] [EC:6.3.1.2]
110494773  shmt2; serine hydroxymethyltransferase, mitochondrial isoform X1 [KO:K00600] [EC:2.1.2.1]
110514212  serine hydroxymethyltransferase, cytosolic-like [KO:K00600] [EC:2.1.2.1]
110514494  serine hydroxymethyltransferase, cytosolic-like [KO:K00600] [EC:2.1.2.1]
110535832  gldc; glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
110525447  glycine dehydrogenase (decarboxylating), mitochondrial isoform X1 [KO:K00281] [EC:1.4.4.2]
118965936  aminomethyltransferase, mitochondrial-like [KO:K00605] [EC:2.1.2.10]
110492324  aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
110521345  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
110492846  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
110521627  glycine cleavage system H protein, mitochondrial [KO:K02437]
110496216  gcsha; glycine cleavage system protein H (aminomethyl carrier), a [KO:K02437]
110506512  gcshb; glycine cleavage system protein H (aminomethyl carrier), b [KO:K02437]
110526391  glycine cleavage system H protein, mitochondrial isoform X2 [KO:K02437]
110524626  hyi; putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
110494647  glycerate kinase [KO:K11529] [EC:2.7.1.165]
110485610  4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
110487262  4-hydroxy-2-oxoglutarate aldolase, mitochondrial-like [KO:K18123] [EC:4.1.3.16]
110495055  kynurenine formamidase-like isoform X1 [KO:K01432] [EC:3.5.1.9]
110485515  kynurenine formamidase isoform X1 [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
omy00010  Glycolysis / Gluconeogenesis
omy00020  Citrate cycle (TCA cycle)
omy00030  Pentose phosphate pathway
omy00053  Ascorbate and aldarate metabolism
omy00071  Fatty acid degradation
omy00230  Purine metabolism
omy00250  Alanine, aspartate and glutamate metabolism
omy00260  Glycine, serine and threonine metabolism
omy00620  Pyruvate metabolism
omy00750  Vitamin B6 metabolism
omy00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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