KEGG   PATHWAY: pag00630
Entry
pag00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas aeruginosa LESB58
Class
Metabolism; Carbohydrate metabolism
Pathway map
pag00630  Glyoxylate and dicarboxylate metabolism
pag00630

Module
pag_M00621  Glycine cleavage system [PATH:pag00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas aeruginosa LESB58 [GN:pag]
Gene
PLES_24711  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
PLES_27391  probable AMP-binding enzyme [KO:K01895] [EC:6.2.1.1]
PLES_51181  acsB; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
PLES_44291  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
PLES_04781  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
PLES_37471  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
PLES_37671  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
PLES_35421  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
PLES_10521  probable acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PLES_35931  probable acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PLES_27411  probable acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PLES_33221  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PLES_51701  probable acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PLES_17641  phaJ1; (R)-specific enoyl-CoA hydratase [KO:K17865] [EC:4.2.1.55]
PLES_57501  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
PLES_57491  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
PLES_57481  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
PLES_49981  katB; catalase [KO:K03781] [EC:1.11.1.6]
PLES_31791  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
PLES_06911  katA; catalase [KO:K03781] [EC:1.11.1.6]
PLES_10811  probable 2-hydroxyacid dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
PLES_50111  hprA; glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
PLES_06051  probable phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
PLES_20891  probable hydrolase [KO:K01091] [EC:3.1.3.18]
PLES_00661  putative phosphatase [KO:K01091] [EC:3.1.3.18]
PLES_02921  probable glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_02941  spuB; probable glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_17081  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_32821  probable glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_37631  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_55091  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_59041  probable glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_59181  probable glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PLES_49871  glyA3; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PLES_58101  glyA1; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PLES_28501  glyA2; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PLES_28491  gcvP2; glycine cleavage system protein P2 [KO:K00281] [EC:1.4.4.2]
PLES_56071  gcvP1; glycine cleavage system protein P1 [KO:K00281] [EC:1.4.4.2]
PLES_56091  gcvT1; glycine-cleavage system protein T1 [KO:K00605] [EC:2.1.2.10]
PLES_28521  gcvT2; glycine cleavage system protein T2 [KO:K00605] [EC:2.1.2.10]
PLES_30541  lpdV; lipoamide dehydrogenase-Val [KO:K00382] [EC:1.8.1.4]
PLES_37401  lpdG; lipoamide dehydrogenase-glc [KO:K00382] [EC:1.8.1.4]
PLES_26171  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
PLES_52141  lpd3; dihydrolipoamide dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
PLES_56081  gcvH1; glycine cleavage system protein H1 [KO:K02437]
PLES_28481  gcvH2; glycine cleavage system protein H2 [KO:K02437]
PLES_51811  putative glycine cleavage system H protein [KO:K02437]
PLES_39101  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
PLES_39111  putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
PLES_39121  probable oxidoreductase [KO:K00042] [EC:1.1.1.60]
PLES_42711  Putative glycerate kinase [KO:K00865] [EC:2.7.1.165]
PLES_39131  putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
PLES_19281  probable aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PLES_18871  2-keto-3-deoxy-6-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PLES_51961  fdnG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
PLES_51971  Twin-arginine translocation pathway signal [KO:K00123] [EC:1.17.1.9]
PLES_51951  fdnH; nitrate-inducible formate dehydrogenase, beta subunit [KO:K00124]
PLES_51941  fdnI; nitrate-inducible formate dehydrogenase, gamma subunit [KO:K00127]
PLES_32401  kynB; kynurenine formamidase, KynB [KO:K07130] [EC:3.5.1.9]
PLES_58151  purU2; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
PLES_46921  purU1; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
PLES_54811  hutG; N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pag00010  Glycolysis / Gluconeogenesis
pag00020  Citrate cycle (TCA cycle)
pag00030  Pentose phosphate pathway
pag00053  Ascorbate and aldarate metabolism
pag00071  Fatty acid degradation
pag00230  Purine metabolism
pag00250  Alanine, aspartate and glutamate metabolism
pag00260  Glycine, serine and threonine metabolism
pag00620  Pyruvate metabolism
pag00710  Carbon fixation by Calvin cycle
pag00750  Vitamin B6 metabolism
pag00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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