KEGG   PATHWAY: pag00230
Entry
pag00230                    Pathway                                
Name
Purine metabolism - Pseudomonas aeruginosa LESB58
Class
Metabolism; Nucleotide metabolism
Pathway map
pag00230  Purine metabolism
pag00230

Module
pag_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pag00230]
pag_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pag00230]
pag_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pag00230]
pag_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pag00230]
pag_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pag00230]
pag_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pag00230]
pag_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pag00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas aeruginosa LESB58 [GN:pag]
Gene
PLES_53571  aspP; adenosine diphosphate sugar pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
PLES_55691  putative DP compound hydrolase [KO:K08312] [EC:3.6.1.-]
PLES_57171  algC; phosphomannomutase AlgC [KO:K15778] [EC:5.4.2.8 5.4.2.2]
PLES_50561  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
PLES_19521  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
PLES_52401  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
PLES_43711  purN; phosphoribosylaminoimidazole synthetase [KO:K11175] [EC:2.1.2.2]
PLES_12291  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
PLES_12161  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
PLES_43701  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
PLES_58201  purK; phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
PLES_58211  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
PLES_43121  purC; phosphoribosylaminoimidazole-succinocarboxamidesynthase [KO:K01923] [EC:6.3.2.6]
PLES_15161  probable lyase [KO:K01756] [EC:4.3.2.2]
PLES_15171  probable lyase [KO:K01756] [EC:4.3.2.2]
PLES_24761  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
PLES_52391  purH; phosphoribosylaminoimidazolecarboxamideformyltra nsferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
PLES_37851  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
PLES_14101  surE; survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
PLES_55701  probable hydrolase [KO:K20881] [EC:3.1.3.-]
PLES_37541  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
PLES_49261  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
PLES_39441  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
PLES_50311  probable purine/pyrimidine phosphoribosyl transferase [KO:K00760] [EC:2.4.2.8]
PLES_12041  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
PLES_11671  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
PLES_03841  putative Ham1 protein [KO:K01519] [EC:3.6.1.66]
PLES_56931  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
PLES_38041  xdhA; xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
PLES_38051  xdhB; xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
PLES_33901  probable hydroxylase large subunit [KO:K11177] [EC:1.17.1.4]
PLES_33911  probable hydroxylase molybdopterin-containing subunit [KO:K11178] [EC:1.17.1.4]
PLES_33921  probable ferredoxin [KO:K13483]
PLES_12051  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
PLES_38071  probable guanine deaminase [KO:K01487] [EC:3.5.4.3]
PLES_01351  probable guanine deaminase [KO:K01487] [EC:3.5.4.3]
PLES_27961  probable deaminase [KO:K01487] [EC:3.5.4.3]
PLES_57311  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
PLES_58931  nrdJa; NrdJa [KO:K00525] [EC:1.17.4.1]
PLES_41651  nrdA; NrdA, catalytic component of class Ia ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
PLES_41661  nrdB; NrdB, tyrosyl radical-harboring component of class Ia ribonucleotide reductase [KO:K00526] [EC:1.17.4.1]
PLES_34031  putative ribonucleotide reductase [KO:K21636] [EC:1.1.98.6]
PLES_41951  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
PLES_20171  putative deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
PLES_57331  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
PLES_56351  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
PLES_43821  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
PLES_18501  cyaB; CyaB [KO:K01768] [EC:4.6.1.1]
PLES_56661  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
PLES_53241  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
PLES_10051  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
PLES_08561  putative decarboxylase family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
PLES_01491  probable adenosine deaminase [KO:K21053] [EC:3.5.4.2]
PLES_12981  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
PLES_43811  conserved hypothetical protein [KO:K04765] [EC:3.6.1.9]
PLES_53551  putative phosphohydrolases [KO:K03651] [EC:3.1.4.53]
PLES_05871  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
PLES_48211  cysN; ATP sulfurylase GTP-binding subunit/APS kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
PLES_48221  cysD; ATP sulfurylase small subunit [KO:K00957] [EC:2.7.7.4]
PLES_38921  putative transthyretin family protein [KO:K07127] [EC:3.5.2.17]
PLES_38941  hypothetical protein [KO:K13485] [EC:4.1.1.97]
PLES_38931  putative polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
PLES_38951  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
PLES_41791  conserved hypothetical protein [KO:K14977] [EC:3.5.3.26]
PLES_38961  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
PLES_52541  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
PLES_52531  ureB; urease beta subunit [KO:K01429] [EC:3.5.1.5]
PLES_52511  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
PLES_55651  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pag00030  Pentose phosphate pathway
pag00220  Arginine biosynthesis
pag00250  Alanine, aspartate and glutamate metabolism
pag00260  Glycine, serine and threonine metabolism
pag00340  Histidine metabolism
pag00630  Glyoxylate and dicarboxylate metabolism
pag00730  Thiamine metabolism
pag00740  Riboflavin metabolism
pag00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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