KEGG   PATHWAY: phh00630
Entry
phh00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudonocardia sp. HH130630-07
Class
Metabolism; Carbohydrate metabolism
Pathway map
phh00630  Glyoxylate and dicarboxylate metabolism
phh00630

Module
phh_M00621  Glycine cleavage system [PATH:phh00630]
phh_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:phh00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudonocardia sp. HH130630-07 [GN:phh]
Gene
AFB00_22475  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
AFB00_09240  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
AFB00_19815  malate synthase G [KO:K01638] [EC:2.3.3.9]
AFB00_00355  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
AFB00_07975  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
AFB00_18460  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
AFB00_18465  hypothetical protein [KO:K01647] [EC:2.3.3.1]
AFB00_25265  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
AFB00_10530  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AFB00_06750  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AFB00_04585  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AFB00_07850  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AFB00_12675  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AFB00_12925  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AFB00_31100  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AFB00_18440  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
AFB00_04590  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
AFB00_04680  protein meaA [KO:K14447] [EC:5.4.99.63]
AFB00_15915  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
AFB00_15990  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
AFB00_15985  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit [KO:K27095]
AFB00_31065  propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
AFB00_26555  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
AFB00_26560  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
AFB00_19265  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
AFB00_19420  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
AFB00_19810  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
AFB00_20895  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
AFB00_19805  dehydrogenase [KO:K11472] [EC:1.1.99.14]
AFB00_19800  glycolate oxidase [KO:K11473] [EC:1.1.99.14]
AFB00_09425  catalase [KO:K03781] [EC:1.11.1.6]
AFB00_22580  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
AFB00_22420  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
AFB00_01515  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AFB00_01565  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AFB00_16015  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AFB00_04760  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AFB00_18110  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AFB00_26415  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
AFB00_01425  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
AFB00_26170  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
AFB00_01455  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AFB00_26440  glycine cleavage system protein H [KO:K02437]
AFB00_24770  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
AFB00_24780  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
AFB00_24710  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
AFB00_24705  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
AFB00_24775  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
AFB00_24765  glycerate kinase [KO:K00865] [EC:2.7.1.165]
AFB00_01400  hypothetical protein [KO:K00865] [EC:2.7.1.165]
AFB00_07680  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
AFB00_28880  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
AFB00_26760  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
AFB00_16570  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
AFB00_19985  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
AFB00_03365  dehydrogenase [KO:K00123] [EC:1.17.1.9]
AFB00_03370  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
AFB00_03375  ferredoxin [KO:K00124]
AFB00_08095  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AFB00_18155  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
phh00010  Glycolysis / Gluconeogenesis
phh00020  Citrate cycle (TCA cycle)
phh00030  Pentose phosphate pathway
phh00053  Ascorbate and aldarate metabolism
phh00071  Fatty acid degradation
phh00230  Purine metabolism
phh00250  Alanine, aspartate and glutamate metabolism
phh00260  Glycine, serine and threonine metabolism
phh00620  Pyruvate metabolism
phh00710  Carbon fixation by Calvin cycle
phh00750  Vitamin B6 metabolism
phh00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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