KEGG   PATHWAY: qlo00480
Entry
qlo00480                    Pathway                                
Name
Glutathione metabolism - Quercus lobata (valley oak)
Class
Metabolism; Metabolism of other amino acids
Pathway map
qlo00480  Glutathione metabolism
qlo00480

Module
qlo_M00118  Glutathione biosynthesis, glutamate => glutathione [PATH:qlo00480]
Other DBs
GO: 0006749
Organism
Quercus lobata (valley oak) [GN:qlo]
Gene
115994980  glutathione hydrolase 1-like isoform X1 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
115975602  glutathione hydrolase 3 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
115960247  gamma-glutamylcyclotransferase 2-3 isoform X1 [KO:K22596] [EC:4.3.2.9]
115972252  gamma-glutamylcyclotransferase 2-1 [KO:K22596] [EC:4.3.2.9]
115968744  5-oxoprolinase [KO:K01469] [EC:3.5.2.9]
115951686  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
115971319  glutamate--cysteine ligase, chloroplastic-like isoform X1 [KO:K01919] [EC:6.3.2.2]
115981748  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
115977257  leucine aminopeptidase 1-like [KO:K01255] [EC:3.4.11.1]
115970875  puromycin-sensitive aminopeptidase isoform X1 [KO:K01256] [EC:3.4.11.2]
115960090  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115960419  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115960420  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115976187  microsomal glutathione S-transferase 3 [KO:K00799] [EC:2.5.1.18]
115993998  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115994123  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115994124  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115994257  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
115960564  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115960565  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115960714  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115960772  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115960788  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115961026  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115995261  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115995262  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115962328  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115962422  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115962820  glutathione S-transferase U9 [KO:K00799] [EC:2.5.1.18]
115977733  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115963422  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
115978147  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
115979415  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115979585  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115979586  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115965666  glutathione S-transferase U7-like [KO:K00799] [EC:2.5.1.18]
115965928  glutathione S-transferase U7-like [KO:K00799] [EC:2.5.1.18]
115981248  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115981265  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115981266  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115981617  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115981626  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115981807  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115967894  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
115981861  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115981955  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115981971  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115982044  glutathione S-transferase U10-like [KO:K00799] [EC:2.5.1.18]
115949995  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115982959  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
115982961  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
115982962  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
115982963  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
115983220  glutathione S-transferase U19-like [KO:K00799] [EC:2.5.1.18]
115983221  glutathione S-transferase U19-like [KO:K00799] [EC:2.5.1.18]
115983294  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115983312  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115983449  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115983545  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115983549  glutathione S-transferase U19-like [KO:K00799] [EC:2.5.1.18]
115951031  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115952116  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
115983767  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115984001  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115984072  probable glutathione S-transferase parC [KO:K00799] [EC:2.5.1.18]
115984105  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
115953078  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
115969875  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
115970460  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
115970461  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115986775  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115986776  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
115953407  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
115953408  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
115953409  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
115953410  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
115953413  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
115953971  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
115954006  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
115971760  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115971761  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115971786  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
115971787  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115971788  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115987005  glutathione S-transferase U19-like [KO:K00799] [EC:2.5.1.18]
115987013  glutathione S-transferase U19-like [KO:K00799] [EC:2.5.1.18]
115987052  probable glutathione S-transferase isoform X1 [KO:K00799] [EC:2.5.1.18]
115987199  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115987371  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115987382  probable glutathione S-transferase isoform X1 [KO:K00799] [EC:2.5.1.18]
115987749  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115987750  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115954205  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
115971814  glutathione S-transferase F13 [KO:K00799] [EC:2.5.1.18]
115971886  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115971949  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115972081  glutathione S-transferase F13-like [KO:K00799] [EC:2.5.1.18]
115972331  glutathione S-transferase T1 [KO:K00799] [EC:2.5.1.18]
115972366  glutathione S-transferase PARB-like [KO:K00799] [EC:2.5.1.18]
115972409  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
115988523  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
115988524  glutathione S-transferase L3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
115988869  glutathione S-transferase L3-like [KO:K00799] [EC:2.5.1.18]
115955386  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
115974626  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115974631  probable glutathione S-transferase isoform X1 [KO:K00799] [EC:2.5.1.18]
115957852  protein IN2-1 homolog B-like isoform X1 [KO:K00799] [EC:2.5.1.18]
115957853  protein IN2-1 homolog B-like isoform X1 [KO:K00799] [EC:2.5.1.18]
115959485  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
115993839  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
115967123  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
115955933  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
115975953  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
115994385  glutathione reductase, cytosolic [KO:K00383] [EC:1.8.1.7]
115971224  glutathione reductase, chloroplastic [KO:K00383] [EC:1.8.1.7]
115976624  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
115984274  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
115984341  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
115976027  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
115976028  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
115976183  6-phosphogluconate dehydrogenase, decarboxylating 2 [KO:K00033] [EC:1.1.1.44 1.1.1.343]
115976846  6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic [KO:K00033] [EC:1.1.1.44 1.1.1.343]
115976510  glucose-6-phosphate 1-dehydrogenase 6, cytoplasmic [KO:K00036] [EC:1.1.1.49 1.1.1.363]
115981790  inactive glucose-6-phosphate 1-dehydrogenase 4, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
115981889  inactive glucose-6-phosphate 1-dehydrogenase 4, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
115982131  glucose-6-phosphate 1-dehydrogenase, chloroplastic [KO:K00036] [EC:1.1.1.49 1.1.1.363]
115987935  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
115955533  glucose-6-phosphate 1-dehydrogenase 1, chloroplastic isoform X1 [KO:K00036] [EC:1.1.1.49 1.1.1.363]
115966019  probable glutathione peroxidase 2 [KO:K00432] [EC:1.11.1.9]
115969935  probable glutathione peroxidase 8 [KO:K00432] [EC:1.11.1.9]
115969959  probable glutathione peroxidase 8 [KO:K00432] [EC:1.11.1.9]
115971166  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
115971547  probable glutathione peroxidase 4 [KO:K00432] [EC:1.11.1.9]
115989724  probable phospholipid hydroperoxide glutathione peroxidase isoform X1 [KO:K00432] [EC:1.11.1.9]
115974831  phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic-like [KO:K00432] [EC:1.11.1.9]
115951004  1-Cys peroxiredoxin [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
115978240  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
115960231  spermine synthase [KO:K00797] [EC:2.5.1.16]
115965642  spermidine synthase 2-like [KO:K00797] [EC:2.5.1.16]
115982669  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
115960304  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
115994468  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
115968592  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
115953030  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
115988749  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
115974948  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
115994875  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
115976434  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
115950907  ribonucleoside-diphosphate reductase small chain A isoform X1 [KO:K10808] [EC:1.17.4.1]
Compound
C00005  NADPH
C00006  NADP+
C00024  Acetyl-CoA
C00025  L-Glutamate
C00037  Glycine
C00051  Glutathione
C00072  Ascorbate
C00077  L-Ornithine
C00097  L-Cysteine
C00127  Glutathione disulfide
C00134  Putrescine
C00151  L-Amino acid
C00315  Spermidine
C00669  gamma-L-Glutamyl-L-cysteine
C00750  Spermine
C01322  RX
C01419  Cys-Gly
C01672  Cadaverine
C01879  5-Oxoproline
C02090  Trypanothione
C02320  R-S-Glutathione
C03170  Trypanothione disulfide
C03646  Bis-gamma-glutamylcystine
C03740  (5-L-Glutamyl)-L-amino acid
C05422  Dehydroascorbate
C05726  S-Substituted L-cysteine
C05727  S-Substituted N-acetyl-L-cysteine
C05729  R-S-Cysteinylglycine
C05730  Glutathionylspermidine
C16562  Glutathionylspermine
C16563  Bis(glutathionyl)spermine
C16564  Bis(glutathionyl)spermine disulfide
C16565  Aminopropylcadaverine
C16566  Glutathionylaminopropylcadaverine
C16567  Homotrypanothione
C16568  Homotrypanothione disulfide
C16663  Tryparedoxin
C16664  Tryparedoxin disulfide
Reference
PMID:12675513
  Authors
Josch C, Klotz LO, Sies H.
  Title
Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver.
  Journal
Biol Chem 384:213-8 (2003)
DOI:10.1515/BC.2003.023
Reference
PMID:18482986
  Authors
Chu L, Lai Y, Xu X, Eddy S, Yang S, Song L, Kolodrubetz D.
  Title
A 52-kDa leucyl aminopeptidase from treponema denticola is a cysteinylglycinase that mediates the second step of glutathione metabolism.
  Journal
J Biol Chem 283:19351-8 (2008)
DOI:10.1074/jbc.M801034200
Reference
PMID:14583094
  Authors
Cappiello M, Lazzarotti A, Buono F, Scaloni A, D'Ambrosio C, Amodeo P, Mendez BL, Pelosi P, Del Corso A, Mura U.
  Title
New role for leucyl aminopeptidase in glutathione turnover.
  Journal
Biochem J 378:35-44 (2004)
DOI:10.1042/BJ20031336
Reference
PMID:11157967
  Authors
Suzuki H, Kamatani S, Kim ES, Kumagai H.
  Title
Aminopeptidases A, B, and N and dipeptidase D are the four cysteinylglycinases of Escherichia coli K-12.
  Journal
J Bacteriol 183:1489-90 (2001)
DOI:10.1128/JB.183.4.1489-1490.2001
Reference
PMID:15610825
  Authors
Oza SL, Shaw MP, Wyllie S, Fairlamb AH.
  Title
Trypanothione biosynthesis in Leishmania major.
  Journal
Mol Biochem Parasitol 139:107-16 (2005)
DOI:10.1016/j.molbiopara.2004.10.004
Reference
PMID:12049631
  Authors
Oza SL, Ariyanayagam MR, Fairlamb AH.
  Title
Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata.
  Journal
Biochem J 364:679-86 (2002)
DOI:10.1042/BJ20011370
Reference
PMID:9677355
  Authors
Tetaud E, Manai F, Barrett MP, Nadeau K, Walsh CT, Fairlamb AH.
  Title
Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata.
  Journal
J Biol Chem 273:19383-90 (1998)
DOI:10.1074/jbc.273.31.19383
Reference
PMID:12750367
  Authors
Ariyanayagam MR, Oza SL, Mehlert A, Fairlamb AH.
  Title
Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi.
  Journal
J Biol Chem 278:27612-9 (2003)
DOI:10.1074/jbc.M302750200
Reference
PMID:12967709
  Authors
Oza SL, Ariyanayagam MR, Aitcheson N, Fairlamb AH.
  Title
Properties of trypanothione synthetase from Trypanosoma brucei.
  Journal
Mol Biochem Parasitol 131:25-33 (2003)
DOI:10.1016/S0166-6851(03)00176-2
Reference
PMID:12121990
  Authors
Oza SL, Tetaud E, Ariyanayagam MR, Warnon SS, Fairlamb AH.
  Title
A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.
  Journal
J Biol Chem 277:35853-61 (2002)
DOI:10.1074/jbc.M204403200
Reference
PMID:15537651
  Authors
Comini M, Menge U, Wissing J, Flohe L.
  Title
Trypanothione synthesis in crithidia revisited.
  Journal
J Biol Chem 280:6850-60 (2005)
DOI:10.1074/jbc.M404486200
Reference
PMID:7813456
  Authors
Hunter KJ, Le Quesne SA, Fairlamb AH.
  Title
Identification and biosynthesis of N1,N9-bis(glutathionyl)aminopropylcadaverine (homotrypanothione) in Trypanosoma cruzi.
  Journal
Eur J Biochem 226:1019-27 (1994)
DOI:10.1111/j.1432-1033.1994.t01-1-01019.x
Reference
PMID:12751784
  Authors
Krauth-Siegel RL, Meiering SK, Schmidt H.
  Title
The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
  Journal
Biol Chem 384:539-49 (2003)
DOI:10.1515/BC.2003.062
Reference
PMID:18395526
  Authors
Krauth-Siegel RL, Comini MA.
  Title
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism.
  Journal
Biochim Biophys Acta 1780:1236-48 (2008)
DOI:10.1016/j.bbagen.2008.03.006
Reference
PMID:8892297
  Authors
Krauth-Siegel RL, Ludemann H.
  Title
Reduction of dehydroascorbate by trypanothione.
  Journal
Mol Biochem Parasitol 80:203-8 (1996)
DOI:10.1016/0166-6851(96)02689-8
Reference
PMID:11150302
  Authors
Dormeyer M, Reckenfelderbaumer N, Ludemann H, Krauth-Siegel RL.
  Title
Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase.
  Journal
J Biol Chem 276:10602-6 (2001)
DOI:10.1074/jbc.M010352200
Reference
PMID:12949079
  Authors
Schmidt H, Krauth-Siegel RL.
  Title
Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei.
  Journal
J Biol Chem 278:46329-36 (2003)
DOI:10.1074/jbc.M305338200
Reference
PMID:9851611
  Authors
Tetaud E, Fairlamb AH.
  Title
Cloning, expression and reconstitution of the trypanothione-dependent peroxidase system of Crithidia fasciculata.
  Journal
Mol Biochem Parasitol 96:111-23 (1998)
DOI:10.1016/S0166-6851(98)00120-0
Reference
PMID:12446213
  Authors
Castro H, Sousa C, Santos M, Cordeiro-da-Silva A, Flohe L, Tomas AM.
  Title
Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum.
  Journal
Free Radic Biol Med 33:1552-62 (2002)
DOI:10.1016/S0891-5849(02)01089-4
Reference
PMID:10713147
  Authors
Wilkinson SR, Temperton NJ, Mondragon A, Kelly JM.
  Title
Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi.
  Journal
J Biol Chem 275:8220-5 (2000)
DOI:10.1074/jbc.275.11.8220
Reference
PMID:17922848
  Authors
Konig J, Fairlamb AH.
  Title
A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major.
  Journal
FEBS J 274:5643-58 (2007)
DOI:10.1111/j.1742-4658.2007.06087.x
Reference
PMID:12466271
  Authors
Hillebrand H, Schmidt A, Krauth-Siegel RL.
  Title
A second class of peroxidases linked to the trypanothione metabolism.
  Journal
J Biol Chem 278:6809-15 (2003)
DOI:10.1074/jbc.M210392200
Reference
PMID:14982633
  Authors
Soksawatmaekhin W, Kuraishi A, Sakata K, Kashiwagi K, Igarashi K.
  Title
Excretion and uptake of cadaverine by CadB and its physiological functions in Escherichia coli.
  Journal
Mol Microbiol 51:1401-12 (2004)
DOI:10.1046/j.1365-2958.2003.03913.x
Reference
PMID:6798961
  Authors
Pegg AE, Shuttleworth K, Hibasami H.
  Title
Specificity of mammalian spermidine synthase and spermine synthase.
  Journal
Biochem J 197:315-20 (1981)
DOI:10.1042/bj1970315
Related
pathway
qlo00220  Arginine biosynthesis
qlo00250  Alanine, aspartate and glutamate metabolism
qlo00270  Cysteine and methionine metabolism
qlo00430  Taurine and hypotaurine metabolism
qlo00460  Cyanoamino acid metabolism
KO pathway
ko00480   
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