KEGG   PATHWAY: sacc00630
Entry
sacc00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Saccharomonospora xinjiangensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
sacc00630  Glyoxylate and dicarboxylate metabolism
sacc00630

Module
sacc_M00012  Glyoxylate cycle [PATH:sacc00630]
sacc_M00621  Glycine cleavage system [PATH:sacc00630]
sacc_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sacc00630]
Other DBs
GO: 0046487 0043648
Organism
Saccharomonospora xinjiangensis [GN:sacc]
Gene
EYD13_15565  icl; Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
EYD13_07860  acsA2; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
EYD13_12605  acsA3; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
EYD13_19960  acsA4; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
EYD13_05245  aceB1; Malate synthase [KO:K01638] [EC:2.3.3.9]
EYD13_15560  aceB2; Malate synthase [KO:K01638] [EC:2.3.3.9]
EYD13_10570  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
EYD13_18680  gltA2; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
EYD13_18720  citA; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
EYD13_12480  acnA; Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
EYD13_16800  fadA2; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
EYD13_21605  fadI; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
EYD13_17680  fadA3; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
EYD13_15745  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EYD13_12070  fadA1; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
EYD13_15750  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein [KO:K05606] [EC:5.1.99.1]
EYD13_03280  accA1; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
EYD13_03300  accD1; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
EYD13_03295  hypothetical protein [KO:K27095]
EYD13_03170  mutA; Methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
EYD13_03175  mutB; Methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
EYD13_16785  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
EYD13_21295  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
EYD13_01315  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
EYD13_01310  putative FAD-linked oxidoreductase [KO:K11472] [EC:1.1.99.14]
EYD13_01305  lutA1; Lactate utilization protein A [KO:K11473] [EC:1.1.99.14]
EYD13_07315  katE; Catalase HPII [KO:K03781] [EC:1.11.1.6]
EYD13_09990  katA; Catalase [KO:K03781] [EC:1.11.1.6]
EYD13_07065  Putative 2-hydroxyacid dehydrogenase [KO:K00015] [EC:1.1.1.26]
EYD13_18875  gph; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
EYD13_04070  glnA1; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
EYD13_04115  glnA2; Glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
EYD13_07195  glyA1; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
EYD13_11580  glyA2; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EYD13_07180  gcvP; Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
EYD13_07185  gcvT1; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
EYD13_05730  pdhD1; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EYD13_06045  lpdC; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EYD13_11790  pdhD2; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EYD13_07190  gcvH1; Glycine cleavage system H protein [KO:K02437]
EYD13_12590  gcvH2; Glycine cleavage system H protein [KO:K02437]
EYD13_11295  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
EYD13_11305  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
EYD13_11300  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EYD13_07060  garK1; Glycerate 2-kinase [KO:K00865] [EC:2.7.1.165]
EYD13_11290  garK2; Glycerate 2-kinase [KO:K00865] [EC:2.7.1.165]
EYD13_16760  dmlA; D-malate dehydrogenase [decarboxylating] [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
EYD13_15215  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EYD13_16965  kgd; Multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
EYD13_09620  fdhA1; Formate dehydrogenase subunit alpha precursor [KO:K00123] [EC:1.17.1.9]
EYD13_09625  fdnG; Formate dehydrogenase, nitrate-inducible, major subunit precursor [KO:K00123] [EC:1.17.1.9]
EYD13_09630  fdnH; Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit [KO:K00124]
EYD13_01495  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
EYD13_10715  amdA; Acetamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sacc00010  Glycolysis / Gluconeogenesis
sacc00020  Citrate cycle (TCA cycle)
sacc00030  Pentose phosphate pathway
sacc00053  Ascorbate and aldarate metabolism
sacc00071  Fatty acid degradation
sacc00230  Purine metabolism
sacc00250  Alanine, aspartate and glutamate metabolism
sacc00260  Glycine, serine and threonine metabolism
sacc00620  Pyruvate metabolism
sacc00710  Carbon fixation by Calvin cycle
sacc00750  Vitamin B6 metabolism
sacc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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